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Chemical Structure| 88615-68-3 Chemical Structure| 88615-68-3

Structure of 88615-68-3

Chemical Structure| 88615-68-3

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Product Details of [ 88615-68-3 ]

CAS No. :88615-68-3
Formula : C6H15NO
M.W : 117.19
SMILES Code : CC(C)(C)OCCN
MDL No. :MFCD03453520

Safety of [ 88615-68-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H226-H302-H312-H332-H314
Precautionary Statements:P210-P233-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378-P403+P235-P405-P501
Class:8(3)
UN#:2734
Packing Group:

Application In Synthesis of [ 88615-68-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 88615-68-3 ]

[ 88615-68-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 88615-68-3 ]
  • [ 369-26-6 ]
  • [ 1426531-70-5 ]
YieldReaction ConditionsOperation in experiment
With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; In tetrahydrofuran; at 90℃; for 16h; Step 1 : 3-Amino-N-(2-tert-butoxyethyl)-4-fluorobenzamide A mixture comprising 2-tert-butoxyethanamine (1 .2 g, 5.12 mmol, 50percentw/w) and <strong>[369-26-6]methyl 3-amino-4-fluorobenzoate</strong> (0.866 g, 5.12 mmol) in THF (10 ml) was treated with TBD (0.713 g, 5.12 mmol) and heated at 90 °C for 16 hrs. After cooling to RT, the solvent was removed in vacuo and the residue was partitioned between water and EtOAc. The organic portion was separated and washed with 10percent aq citric acid (x 2), NaHC03(sat. aq), brine, dried (MgS04) and concentrated in vacuo. Purification of the crude product by chromatography on silica eluting with 0-100percent EtOAc in iso- hexane afforded the title compound as a clear oil;LC-MS: Rt 1.09 mins; MS m/z 255 [M+H]+; Method 2minl_C_v003
 

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