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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 3973-18-0 Chemical Structure| 3973-18-0
Chemical Structure| 3973-18-0

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Propynol Ethoxylate is an ethoxylated surfactant composed of propynol groups. It is commonly used in formulations as an emulsifier and dispersing agent.

Synonyms: Propynol Ethoxylate

4.5 *For Research Use Only !

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Product Details of Propynol Ethoxylate

CAS No. :3973-18-0
Formula : C5H8O2
M.W : 100.12
SMILES Code : C#CCOCCO
Synonyms :
Propynol Ethoxylate
MDL No. :MFCD00099294
InChI Key :GHGCQQRMJCSIBQ-UHFFFAOYSA-N
Pubchem ID :77596

Safety of Propynol Ethoxylate

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H315-H319-H335
Precautionary Statements:P305+P351+P338
Class:3
UN#:1993
Packing Group:

Application In Synthesis of Propynol Ethoxylate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3973-18-0 ]

[ 3973-18-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3973-18-0 ]
  • [ 309947-86-2 ]
  • [ 1562402-17-8 ]
YieldReaction ConditionsOperation in experiment
With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at 0℃; for 3h;Inert atmosphere; General procedure: Bis-boc-adenine1,2 (302 mg, 0.90 mmol) and triphenylphosphine (467 mg, 1.78 mmol) were dissolved in THF (10 mL), and the mixture was stirred at C. 2-(Prop-2-yn-1-yloxy)ethanol3 (134 mg, 1.34 mmol) and a 40% solutionof DEAD in toluene (0.82 mL, 1.79 mmol) were added. The reaction mixture was stirred for 3hours at C and then concentrated under reduced pressure. The residue was purified by flash column chromatography (0-4% CH3OH in CH2Cl2) to give the crude intermediate S1. This was dissolved in CH3OH (3.5 mL) and 3 M HCl (3.5 mL) was added. The reaction mixture was stirred at 45 C for 16 h and then neutralised by the addition of a 0.2 M aqueous solution of Na2CO3. The mixture was concentrated under reduced pressure and then dissolved in DMF followed by filtration and concentration under reduced pressure. The residue was purified by flash column chromatography (0-20% CH3OH in CH2Cl2) to give the product S2 as a white powder (51 mg, 26% over two steps).
 

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