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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 53797-35-6 Chemical Structure| 53797-35-6

Structure of Ribostamycin Sulfate
CAS No.: 53797-35-6

Chemical Structure| 53797-35-6

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Ribostamycin Sulfate is a broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus, which acts through binding to the bacterial 30S and 50S ribosomal subunit , inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and thus causing misreading of mRNA.

Synonyms: Vistamycin sulfate

4.5 *For Research Use Only !

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Product Details of Ribostamycin Sulfate

CAS No. :53797-35-6
Formula : C17H36N4O14S
M.W : 552.55
SMILES Code : O=S(O)(O)=O.O[C@@H]([C@H](O)[C@@H](CN)O1)[C@@H](N)[C@@]1([H])O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@@]2([H])O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
Synonyms :
Vistamycin sulfate
MDL No. :MFCD23380549

Safety of Ribostamycin Sulfate

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H312-H332-H360
Precautionary Statements:P201-P280-P308+P313
Class:6.1
UN#:2811
Packing Group:

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
MDCK cells >100 mM 68 h Evaluate the nephrotoxicity of ribostamycin in MDCK cells, showing no toxicity PMC7403490
HEK293 cells >100 mM 68 h Evaluate the nephrotoxicity of ribostamycin in HEK293 cells, showing no toxicity PMC7403490
bacterial ribosomes 0.13 μM Investigated the impact of Ribostamycin on ribosome subunit rotation dynamics, showing weak effects on rotation dynamics. PMC4522699
Streptococcus pneumoniae (ATCC 49619) 7.2 μM 14 h Evaluate the antibacterial activity of ribostamycin against S. pneumoniae, showing high activity PMC7403490
Haemophilus influenzae (ATCC 49247) 0.5 μM 14 h Evaluate the antibacterial activity of ribostamycin against H. influenzae, showing high activity PMC7403490
Escherichia coli (ATCC 35218) 57.9 μM 14 h Evaluate the antibacterial activity of ribostamycin against β-lactam-resistant E. coli, showing lower activity PMC7403490
Escherichia coli (ATCC 25922) 29.0 μM 14 h Evaluate the antibacterial activity of ribostamycin against E. coli, showing moderate activity PMC7403490

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.81mL

0.36mL

0.18mL

9.05mL

1.81mL

0.90mL

18.10mL

3.62mL

1.81mL

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