Home Cart Sign in  
Chemical Structure| 19103-54-9 Chemical Structure| 19103-54-9

Structure of Salvigenin
CAS No.: 19103-54-9

Chemical Structure| 19103-54-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Salvigenin is a natural polyphenol compound with neuroprotective properties. Salvigenin has antitumor, cytotoxic, and immunomodulatory effects. Salvigenin inhibits H2O2-induced apoptosis.

Synonyms: Psathyrotin

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of Salvigenin

CAS No. :19103-54-9
Formula : C18H16O6
M.W : 328.32
SMILES Code : O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=C(OC)C(O)=C13
Synonyms :
Psathyrotin
MDL No. :MFCD00238678
InChI Key :QCDYOIZVELGOLZ-UHFFFAOYSA-N
Pubchem ID :161271

Safety of Salvigenin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
THP-1 monocytic leukemia cells 10 µg/ml 3 hours Inhibited LPS-induced IL-6 release Front Pharmacol. 2019 May 28;10:573
THP-1 monocytic leukemia cells 10 µg/ml 2 hours Did not inhibit ATP-induced caspase-1 release Front Pharmacol. 2019 May 28;10:573
HepG2 25 µM, 50 µM, 100 µM 24 hours Salvigenin concentration-dependently inhibited HepG2 cell proliferation, migration, and invasion, weakened glycolysis, and suppressed the expression of glycolytic enzymes. Appl Biochem Biotechnol. 2023 Aug;195(8):5217-5237
Huh7 25 µM, 50 µM, 100 µM 24 hours Salvigenin concentration-dependently inhibited Huh7 cell proliferation, migration, and invasion, weakened glycolysis, and suppressed the expression of glycolytic enzymes. Appl Biochem Biotechnol. 2023 Aug;195(8):5217-5237
HCCLM3 0 µM, 25 µM, 50 µM, 100 µM, 200 µM, 400 µM, 800 µM 24 hours Salvigenin concentration-dependently inhibited HCC cell proliferation, migration, and invasion, weakened glycolysis, and suppressed the expression of glycolytic enzymes. Appl Biochem Biotechnol. 2023 Aug;195(8):5217-5237
HepG2 cells 1854.916 mg/L (ethanolic extract) 24 hours To evaluate the induction effect of Salvigenin on CYP2B6 and 3A4 mRNA expression. Results showed that the ethanolic extract moderately induced CYP2B6 mRNA expression (28%-fold shift) and CYP3A4 mRNA expression (44%-fold shift). Front Pharmacol. 2020 Apr 30;11:517
MG63 cells 10-50 µM 24 hours To evaluate the protective effects of Salvigenin against dexamethasone-induced cytotoxicity, results showed Salvigenin significantly restored cell viability Biomedicines. 2025 Mar 3;13(3):614
HuH7 cells 30 µM 72 hours Evaluate the dual activity of Salvigenin on lipid-lowering and mitochondrial stimulation. Results showed that Salvigenin significantly decreased palmitic acid biosynthesis (−22.5%) and stimulated mitochondrial functionality (+15.4%). Antioxidants (Basel). 2021 Jun 29;10(7):1042
Botrytis cinerea UCA992 13.5 ppm (IC50) 72 hours To evaluate the antifungal activity of Salvigenin against Botrytis cinerea, showing an IC50 of 13.5 ppm. Metabolites. 2022 Dec 19;12(12):1292

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
BALB/c nude mice Liver cancer xenograft model Intraperitoneal injection 5 μg/mouse/day, 10 μg/mouse/day Once daily for 4 weeks Salvigenin dose-dependently inhibited the growth and promoted apoptosis of HCC cells in nude mice. Appl Biochem Biotechnol. 2023 Aug;195(8):5217-5237
Rhynchophorus ferrugineus (Red Palm Weevil) Larvae and adults Topical application LD50 11.4 µg/larva Not specified Evaluation of the insecticidal activity of Salvigenin against Red Palm Weevil Plants (Basel). 2022 Apr 16;11(8):1087

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.30mL

15.23mL

3.05mL

1.52mL

30.46mL

6.09mL

3.05mL

References

 

Historical Records

Categories