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Chemical Structure| 56961-10-5 Chemical Structure| 56961-10-5

Structure of SARS-CoV-2-IN-13
CAS No.: 56961-10-5

Chemical Structure| 56961-10-5

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SARS-CoV-2-IN-13 is an effective inhibitor of SARS-CoV-2, with an IC50 of 0.057 μM. It is a chloromethylphenyl derivative with greater stability in human plasma and liver S9 enzyme assays compared to chloromethylphenyl. Oral administration enhances its bioavailability and half-life.

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Product Details of SARS-CoV-2-IN-13

CAS No. :56961-10-5
Formula : C13H8Cl2N2O4
M.W : 327.12
SMILES Code : O=C(NC1=CC=C([N+]([O-])=O)C(Cl)=C1)C2=CC(Cl)=CC=C2O
MDL No. :MFCD34676438

Safety of SARS-CoV-2-IN-13

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H318-H410
Precautionary Statements:P273-P280-P301+P312+P330-P305+P351+P338+P310
Class:9
UN#:3077
Packing Group:

Isoform Comparison

Biological Activity

Description
SARS-CoV-2-IN-13, a potent SARS-CoV-2 inhibitor with an IC50 of 0.057 μM, is a niclosamide analogue. This compound demonstrates enhanced stability in human plasma and liver S9 enzymes assays compared to niclosamide, potentially offering better bioavailability and an extended half-life when taken orally[1].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.06mL

0.61mL

0.31mL

15.28mL

3.06mL

1.53mL

30.57mL

6.11mL

3.06mL

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