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Chemical Structure| 22203-98-1 Chemical Structure| 22203-98-1

Structure of SARS-CoV-2-IN-14
CAS No.: 22203-98-1

Chemical Structure| 22203-98-1

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SARS-CoV-2-IN-14 is a potent SARS-CoV-2 inhibitor with an IC50 of 0.39 μM. It is a niclosamide analogue that exhibits high stability in human plasma and liver S9 enzymes, improving oral bioavailability and half-life.

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Product Details of SARS-CoV-2-IN-14

CAS No. :22203-98-1
Formula : C13H9Cl2NO2
M.W : 282.12
SMILES Code : O=C(NC1=CC=CC(Cl)=C1)C2=CC(Cl)=CC=C2O
MDL No. :MFCD11521629
InChI Key :NXDGLRGDIKDWIF-UHFFFAOYSA-N
Pubchem ID :20196

Safety of SARS-CoV-2-IN-14

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

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Biological Activity

Description
SARS-CoV-2-IN-14, another effective SARS-CoV-2 inhibitor with an IC50 of 0.39 μM, also derives from a niclosamide analogue. It exhibits increased stability in human plasma and liver S9 enzyme assays than niclosamide, which may improve its bioavailability and prolong its half-life upon oral administration[1].

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3.54mL

0.71mL

0.35mL

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1.77mL

35.45mL

7.09mL

3.54mL

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