Structure of Saxagliptin
CAS No.: 361442-04-8
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
Synonyms: BMS-477118
4.5
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CAS No. : | 361442-04-8 |
Formula : | C18H25N3O2 |
M.W : | 315.41 |
SMILES Code : | N#C[C@H]1N(C([C@@H](N)C23CC4(O)CC(C3)CC(C4)C2)=O)[C@@]5([H])C[C@@]5([H])C1 |
Synonyms : |
BMS-477118
|
MDL No. : | MFCD12756398 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302 |
Precautionary Statements: | P280-P305+P351+P338 |
Clinical Trial:
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NCT00316082 | Diabetes | Phase 3 | Completed | - | - |
NCT02148978 | Cystic Fibrosis | UNKNOWN | - | Hadassah Har Hazofim, Jerusale... More >>m, Israel Less << | |
NCT00316082 | - | Completed | - | - | |
NCT01582308 | Type 2 Diabetes Mellitus | Phase 1 | Completed | - | - |
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NCT00121641 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
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NCT01068717 | - | Completed | - | - | |
NCT00897390 | - | Completed | - | - | |
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NCT00757588 | Type 2 Diabetes | Phase 3 | Completed | - | - |
NCT00757588 | - | Completed | - | - | |
NCT01434186 | - | Completed | - | - | |
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NCT00698932 | - | Completed | - | - | |
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NCT00918879 | - | Completed | - | - | |
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NCT02104804 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | China ... More >> Research Site Beijing, China Research Site Changchun, China Research Site Fuzhou, China Research Site Guangzhou, China Research Site Ha'er bing, China Research Site Hefei, China Research Site Nanchang, China Research Site Nanjing, China Research Site Shanghai, China Research Site ShiJiazhuang, China Research Site Shiyan, China Less << |
NCT03714594 | Glucose, Low Blood | Phase 2 | Recruiting | September 2021 | Italy ... More >> Department of Endocrinology and Metabolism, University of Pisa Recruiting Pisa, Italy, 56124 Contact: Stefano Del Prato, MD +39 050 995103 stefano.delprato@med.unipi.it Sub-Investigator: Giuseppe Daniele, MD Less << |
NCT02104804 | - | Completed | - | - | |
NCT02182895 | Diabetes Mellitus | PHASE4 | COMPLETED | 2025-02-17 | Brigham and Women's Hospital, ... More >>Boston, Massachusetts, 02115, United States Less << |
NCT01552005 | Type 2 Diabetes Mellitus (T2D) | COMPLETED | 2025-06-15 | - | |
NCT01765270 | Type 2 Diabetes Mellitus ... More >> Cardiovascular Disease Less << | Phase 4 | Terminated(The study was stopp... More >>ed due to poor enrollment.) Less << | - | United States, Alabama ... More >> Cardiology, PC Birmingham, Alabama, United States, 35211 Cardio-Thoracic Surgeons PC Birmingham, Alabama, United States, 35243 Heart Center Research, LLC Huntsville, Alabama, United States, 35801 United States, Arkansas Sparks Regional Medical Center Fort Smith, Arkansas, United States, 72901 Arkansas Cardiology, PA Little Rock, Arkansas, United States, 72205 United States, California Stanford University Medical Center Palo Alto, California, United States, 94304 United States, Georgia Emory University Hospital Midtown Atlanta, Georgia, United States, 30308 United States, North Carolina Duke University Medical Center (DUMC) Durham, North Carolina, United States, 27710 United States, Virginia Chippenham Medical Center Richmond, Virginia, United States, 23225 United States, West Virginia Charleston Area Medical Center (CAMC) Charleston, West Virginia, United States, 25304 Less << |
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NCT01765270 | - | Terminated(The study was stopp... More >>ed due to poor enrollment.) Less << | - | - | |
NCT02243176 | - | Completed | - | - | |
NCT00935467 | Type 2 Diabetes Mellitus | PHASE1 | COMPLETED | 2025-08-09 | Ppd Development, Lp, Austin, T... More >>exas, 78744, United States Less << |
NCT03660683 | Diabetes Mellitus, Type 2 ... More >> Cardiovascular Diseases Less << | Phase 4 | Recruiting | July 1, 2020 | United States, District of Col... More >>umbia The GW Medical Faculty Associates Recruiting Washington, District of Columbia, United States, 20037 Contact: Hassan Awal, MD hawal@mfa.gwu.edu Less << |
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NCT01441869 | Bioequivalence, Log-transforme... More >>d AUCss and Cmax,ss Values for Saxagliptin and Metformin Less << | Phase 1 | Completed | - | United States, Kansas ... More >> Research Site Overland Park, Kansas, United States Less << |
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NCT02273050 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | China ... More >> Research Site Beijing, China Research Site Changchun, China Research Site Chuangchun, China Research Site Fuzhou, China Research Site Guiyang, China Research Site Ha'er bin, China Research Site Hangzhou, China Research Site Hefei, China Research Site Jinan, China Research Site Nanchang, China Research Site Nanjing, China Research Site Shanghai, China Research Site Shijiazhuang, China Research Site Siping, China Research Site Tianjin, China Research Site Wuxi, China Research Site Yueyang, China Less << |
NCT02182895 | Diabetes Mellitus | PHASE4 | COMPLETED | 2025-02-17 | Brigham and Women's Hospital, ... More >>Boston, Massachusetts, 02115, United States Less << |
NCT02024477 | Type 2 Diabetes | Phase 4 | Active, not recruiting | January 2018 | United States, District of Col... More >>umbia Medical Faculty Associates Inc Washington, District of Columbia, United States, 20037 Less << |
NCT02273050 | - | Completed | - | - | |
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NCT02407899 | Diabetes Mellitus, Type 1 | Phase 4 | Recruiting | June 2018 | China, Hunan ... More >> Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University Recruiting Changsha, Hunan, China, 410011 Contact: Zhiguang Zhou, MD/PhD 86-731-85292154 zhouzg@hotmail.com Less << |
NCT03199053 | Diabetes Mellitus, Type 2 | Phase 3 | Recruiting | December 20, 2021 | - |
NCT02285985 | Type 2 Diabetes Mellitus (T2DM... More >>) Less << | Phase 4 | Active, not recruiting | December 2018 | United States, Arizona ... More >> Carl T. Hayden VA Medical Hospital Phoenix, Arizona, United States, 85012 Less << |
NCT02681094 | - | Completed | - | - | |
NCT02307695 | Type 1 Diabetes | Phase 4 | Unknown | March 2017 | China, Jiangsu ... More >> First Affiliated Hospital, Nanjing Medical University Recruiting Nanjing, Jiangsu, China, 210029 Contact: Tao Yang, PhD 86-25-83718836 ext 6466 yangt@njmu.edu.cn Principal Investigator: Tao Yang, PhD Less << |
NCT02462369 | Microalbuminuria ... More >> Microalbuminuria /Creatinine Ratios ACR Less << | Phase 4 | Unknown | October 2017 | - |
NCT01922817 | Type 1 Diabetes|Hypoglycaemia | PHASE3 | COMPLETED | 2025-04-14 | Clinical research centre, Nine... More >>wells Hospital and Medical School, Dundee, DD1 9SY, United Kingdom Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.17mL 0.63mL 0.32mL |
15.85mL 3.17mL 1.59mL |
31.70mL 6.34mL 3.17mL |
|
Dissolving Methods |
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
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