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Chemical Structure| 1639220-19-1 Chemical Structure| 1639220-19-1

Structure of Sigma-1 receptor antagonist 1
CAS No.: 1639220-19-1

Chemical Structure| 1639220-19-1

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Sigma-1 receptor antagonist 1 is a selective sigma-1 receptor antagonist.

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Product Details of Sigma-1 receptor antagonist 1

CAS No. :1639220-19-1
Formula : C19H23Cl2N3O
M.W : 380.31
SMILES Code : CC1=NC(C2=CC=C(Cl)C=C2)=NC(OCCCN3CCCCC3)=C1Cl
InChI Key :MSFUOAXHQLXDAO-UHFFFAOYSA-N
Pubchem ID :101910737

Safety of Sigma-1 receptor antagonist 1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Sigma-1 receptor antagonist 1

GPCR

Isoform Comparison

Biological Activity

Description
Sigma-1 receptor antagonist 1 is a highly potent and selective antagonist for the sigma-1 receptor (σ1R), displaying strong affinity (Ki = 1.06 nM) for the σ1R receptor. It demonstrates antineuropathic pain efficacy, making it a promising candidate for neuropathic pain management[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.63mL

0.53mL

0.26mL

13.15mL

2.63mL

1.31mL

26.29mL

5.26mL

2.63mL

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