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Chemical Structure| 2523016-96-6 Chemical Structure| 2523016-96-6

Structure of SK-575
CAS No.: 2523016-96-6

Chemical Structure| 2523016-96-6

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SK-575 is an effective protein degradation targeting chimera (PROTAC) PARP1 degrader with an IC50 of 2.30 nM. This compound effectively inhibits the growth of cancer cells carrying BRCA1/2 mutations, suitable for DNA damage repair and cancer research.

4.5 *For Research Use Only !

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Product Details of SK-575

CAS No. :2523016-96-6
Formula : C47H53FN8O8
M.W : 876.97
SMILES Code : O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCCCCCCCCCC(N4CCN(C(C5=CC(CC6=NNC(C7=C6C=CC=C7)=O)=CC=C5F)=O)CC4)=O
MDL No. :MFCD34641822

Safety of SK-575

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of SK-575

epigenetics
DNA

Isoform Comparison

Protocol

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.14mL

0.23mL

0.11mL

5.70mL

1.14mL

0.57mL

11.40mL

2.28mL

1.14mL

 

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