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Chemical Structure| 2546091-70-5 Chemical Structure| 2546091-70-5

Structure of SOP1812
CAS No.: 2546091-70-5

Chemical Structure| 2546091-70-5

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SOP1812 (QN-302) is a naphthalene diimide (ND) derivative with antitumor activity, capable of binding to quadruplex arrangements (G4s) and downregulating multiple cancer gene pathways, with KD values of 4.9 nM and 28.4 nM for hTERT G4 and HuTel21, respectively, suitable for cancer research.

Synonyms: QN-302

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Product Details of SOP1812

CAS No. :2546091-70-5
Formula : C45H57N7O6
M.W : 791.98
SMILES Code : O=C(N(CCCN1CCOCC1)C(C2=C3C4=C(C(N5CCCN6CCOCC6)=O)C=C2NCCN7CCCC7)=O)C3=CC(C8=CC=C(CN9CCCC9)C=C8)=C4C5=O
Synonyms :
QN-302
MDL No. :MFCD34595329

Safety of SOP1812

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of SOP1812

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT06086522 Solid Tumor PHASE1 RECRUITING 2025-12-26 HonorHealth, Scottsdale, Arizo... More >>na, 85251, United States|Yale, New Haven, Connecticut, 06520, United States|START Midwest, Grand Rapids, Michigan, 49546, United States|MD Anderson Cancer Center, Houston, Texas, 77002, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.26mL

0.25mL

0.13mL

6.31mL

1.26mL

0.63mL

12.63mL

2.53mL

1.26mL

 

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