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Chemical Structure| 154563-54-9 Chemical Structure| 154563-54-9

Structure of SP-100030
CAS No.: 154563-54-9

Chemical Structure| 154563-54-9

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SP-100030 is a dual inhibitor of NF-κB and AP-1 with an IC50 of 50 nM for both, inhibiting IL-2, IL-8, and TNF-α production in Jurkat and other T cell lines and reducing symptoms in a mouse model of collagen-induced arthritis (CIA).

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Product Details of SP-100030

CAS No. :154563-54-9
Formula : C14H5ClF9N3O
M.W : 437.65
SMILES Code : O=C(C1=CN=C(Cl)N=C1C(F)(F)F)NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
MDL No. :MFCD00953421

Safety of SP-100030

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of SP-100030

pyroptosis

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.28mL

0.46mL

0.23mL

11.42mL

2.28mL

1.14mL

22.85mL

4.57mL

2.28mL

 

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