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Chemical Structure| 92921-24-9 Chemical Structure| 92921-24-9

Structure of Sulfo-SMCC sodium
CAS No.: 92921-24-9

Chemical Structure| 92921-24-9

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Sulfo-SMCC Crosslinker, or Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a water soluble, heterobifunctional crosslinker. The non-membrane piercing Sulfo-SMCC protein crosslinking reagent can conjugate extracellular proteins. Sulfo-SMCC crosslinker has an 8.3 angstrom, non-cleavable spacer arm.

Synonyms: Sulfo-SMCC sodium

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Product Details of Sulfo-SMCC sodium

CAS No. :92921-24-9
Formula : C16H17N2NaO9S
M.W : 436.37
SMILES Code : O=S(C(C1)C(N(OC(C2CCC(CN3C(C=CC3=O)=O)CC2)=O)C1=O)=O)([O-])=O.[Na+]
Synonyms :
Sulfo-SMCC sodium
InChI Key :VUFNRPJNRFOTGK-UHFFFAOYSA-M
Pubchem ID :4618794

Safety of Sulfo-SMCC sodium

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
Sulfo-SMCC sodium is a hetero-bifunctional, non-cleavable ADC crosslinker with NHS ester and maleimide groups that react with primary amines and sulfhydryl groups, respectively.

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.29mL

0.46mL

0.23mL

11.46mL

2.29mL

1.15mL

22.92mL

4.58mL

2.29mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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