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Chemical Structure| 420092-79-1 Chemical Structure| 420092-79-1

Structure of SW155246
CAS No.: 420092-79-1

Chemical Structure| 420092-79-1

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SW155246 is a selective DNA methyltransferase (DNMT1) inhibitor with IC50 values of 1.2 μM (hDNMT1) and 38 μM (mDNMT3A). This compound can be used in cancer and epigenetic disease research, exhibiting significant epigenetic regulatory effects.

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Product Details of SW155246

CAS No. :420092-79-1
Formula : C16H11ClN2O5S
M.W : 378.79
SMILES Code : O=S(C1=CC=C(Cl)C([N+]([O-])=O)=C1)(NC2=C3C=CC=CC3=C(O)C=C2)=O

Safety of SW155246

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319
Precautionary Statements:P264-P280-P305+P351+P338-P337+P313

Related Pathways of SW155246

epigenetics

Isoform Comparison

Biological Activity

Description
SW155246 is a selective inhibitor of DNA methyltransferase (DNMT1), with IC50s of 1.2 and 38 μM for hDNMT1 and mDNMT3A, respectively. SW155246 is applicable for cancer and other disease research [1].

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1 mM

5 mM

10 mM

2.64mL

0.53mL

0.26mL

13.20mL

2.64mL

1.32mL

26.40mL

5.28mL

2.64mL

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