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Chemical Structure| 1841460-82-9 Chemical Structure| 1841460-82-9

Structure of TH1020
CAS No.: 1841460-82-9

Chemical Structure| 1841460-82-9

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TH1020 is Toll-like receptor (TLR) 5/Flagellin complex antagonist with IC50 of 0.85 μM. TH1020 competes with flagellin for TLR5 binding to inhibit the TLR5:flagellin interaction and subsequent downstream TNF-α secretion.

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Product Details of TH1020

CAS No. :1841460-82-9
Formula : C23H15N7S2
M.W : 453.54
SMILES Code : C12=NC=NC(SC3=NN=C(C4=CC=NC=C4)N3CC5=CC=CC=C5)=C1SC6=NC=CC=C62
MDL No. :MFCD30480930
InChI Key :CBBXTGWSGPEJEE-UHFFFAOYSA-N
Pubchem ID :124203921

Safety of TH1020

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Related Pathways of TH1020

pyroptosis
TLR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.20mL

0.44mL

0.22mL

11.02mL

2.20mL

1.10mL

22.05mL

4.41mL

2.20mL

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