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Chemical Structure| 274693-27-5 Chemical Structure| 274693-27-5

Structure of Ticagrelor
CAS No.: 274693-27-5

Chemical Structure| 274693-27-5

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Ticagrelor is a reversibly and oral active P2Y12 receptor antagonist with Ki of 2 nM, also inhibits CYP2C9 and midazolam 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively.

Synonyms: AZD6140; AR-C 126532XX; Possia

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Product Details of Ticagrelor

CAS No. :274693-27-5
Formula : C23H28F2N6O4S
M.W : 522.57
SMILES Code : O[C@H]1[C@@H](O)[C@H](N2N=NC3=C(N[C@H]4[C@H](C5=CC=C(F)C(F)=C5)C4)N=C(SCCC)N=C32)C[C@@H]1OCCO
Synonyms :
AZD6140; AR-C 126532XX; Possia
MDL No. :MFCD09954148
InChI Key :OEKWJQXRCDYSHL-FNOIDJSQSA-N
Pubchem ID :9871419

Safety of Ticagrelor

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Ticagrelor

GPCR

Isoform Comparison

Biological Activity

Target
  • P2Y receptor

    P2Y12, Ki:2 nM

In Vitro:

Cell Line
Concentration Treated Time Description References
Mouse peritoneal macrophages (PMs) 20μM 30 min Ticagrelor significantly inhibited NLRP3 inflammasome activation, reducing caspase-1 maturation and IL-1β secretion. Cell Mol Immunol. 2021 May;18(5):1278-1289.
Mouse bone marrow-derived macrophages (BMDMs) 10–20μM 30 min Ticagrelor significantly inhibited NLRP3 inflammasome activation, reducing caspase-1 maturation and IL-1β secretion. Cell Mol Immunol. 2021 May;18(5):1278-1289.
Human platelets 10 μM 30 min To assess the effect of ticagrelor on P2Y12 receptor activity in human platelets, the results showed that ticagrelor's antagonism of ADP-stimulated GTP hydrolysis was not reversed after washing. Br J Pharmacol. 2024 Jan;181(1):21-35.
HEK 293T cells 10 μM 30 min To assess the effect of ticagrelor on P2Y12 receptor activation, the results showed that ticagrelor's inverse agonist activity and antagonism of ADP-stimulated P2Y12 receptor activity were not reversed after washing. Br J Pharmacol. 2024 Jan;181(1):21-35.
RAW 264.7 macrophages 0.1 μM 20 h To evaluate oxLDL uptake, results showed that ticagrelor significantly reduced oxLDL uptake in RAW 264.7 macrophages. Drug Des Devel Ther. 2016 Aug 26;10:2691-9.
RAW 264.7 macrophages 0.1 μM 8 h To detect and quantify apoptosis, results showed that ticagrelor significantly reduced apoptosis in RAW 264.7 macrophages. Drug Des Devel Ther. 2016 Aug 26;10:2691-9.
RAW 264.7 macrophages 0.1 μM 20 h Evaluation of oxLDL uptake, results showed that ticagrelor significantly reduced oxLDL uptake in RAW 264.7 macrophages. Drug Des Devel Ther. 2016 Aug 26;10:2691-9.
RAW 264.7 macrophages 0.1 μM 8 h Detection and quantification of apoptosis, results showed that ticagrelor significantly reduced apoptosis in RAW 264.7 macrophages. Drug Des Devel Ther. 2016 Aug 26;10:2691-9.
Human Brain Microvessel Endothelial Cells (HBMVECs) 1 μM 2 h To investigate the protective effects of ticagrelor in an oxygen-glucose deprivation (OGD) stress model. Ticagrelor improved cell viability and promoted the phosphorylation of eNOS and ERK1/2. Sci Rep. 2017 Sep 21;7(1):12088.
human platelets 10 μM 90 min Ticagrelor inhibited Staphylococcus aureus-induced platelet activation and P-selectin expression Sci Transl Med. 2021 Mar 24;13(586):eabd6737.
human platelets 10 μM 2 h Ticagrelor significantly enhanced the killing ability of human platelets against Staphylococcus aureus Sci Transl Med. 2021 Mar 24;13(586):eabd6737.
Human pulmonary artery endothelial cells (HPAECs) 5 μg/mL 3 h To evaluate the effect of Ticagrelor on Hla-induced cytotoxicity and ADAM10 activity, results showed that Ticagrelor did not affect ADAM10 activation or LDH release but improved platelet function. J Clin Invest. 2023 Dec 1;133(23):e168450.
Splenocytes 1, 3, 10 μM 12 hr or 24 hr To evaluate the effect of Ticagrelor on IFN-γ expression in ConA-induced splenocytes, the results showed that Ticagrelor significantly reduced the proportions of CD4+IFN-γ+ and CD8+IFN-γ+ cells. Int J Biol Sci. 2023 Jul 9;19(11):3576-3594.
4T1 mouse breast cancer cells 1 mg/mL, 5 mg/mL 24 h To evaluate the effect of ticagrelor on tumor cell invasion, results showed that ticagrelor significantly inhibited tumor cell invasion. Theranostics. 2017 Feb 26;7(5):1062-1071.
4T1 mouse breast cancer cells 1 mg/mL, 5 mg/mL 24 h To evaluate the effect of ticagrelor on platelet-tumor cell interactions, results showed that ticagrelor significantly inhibited platelet adhesion to tumor cells. Theranostics. 2017 Feb 26;7(5):1062-1071.

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Mice Alum-induced peritonitis model and LPS-induced sepsis model Intraperitoneal injection 50 mg/kg Single injection, lasting 6 hours or 4 hours Ticagrelor significantly mitigated the severity of systemic inflammation, reducing IL-1β and IL-18 secretion, and increased the survival rate of mice. Cell Mol Immunol. 2021 May;18(5):1278-1289.
Mice Apolipoprotein-E-deficient mice Oral 270 mg/kg Once daily for 25 weeks To evaluate the effect of ticagrelor on advanced atherosclerosis, results showed that ticagrelor significantly reduced the relative area of the necrotic core and increased the thickness of the fibrous cap. Drug Des Devel Ther. 2016 Aug 26;10:2691-9.
Mice ApoE−/− mice Oral 270 mg/kg Once daily for 25 weeks Evaluation of the effects of ticagrelor on advanced atherosclerosis, results showed that ticagrelor significantly reduced the relative area of the necrotic core and increased the thickness of the fibrous cap. Drug Des Devel Ther. 2016 Aug 26;10:2691-9.
Mice Transient Middle Cerebral Artery Occlusion (MCAO) Model Oral 10 or 30 mg/kg Administered at 3 and 24 hours before MCAO and 0 and 6 hours after reperfusion To investigate the protective effects of ticagrelor against ischemia-reperfusion injury. Ticagrelor (30 mg/kg) improved neurological deficits, reduced the infarct volume, and improved CBF. Sci Rep. 2017 Sep 21;7(1):12088.
Mice Endotoxemia model Oral gavage 10, 25, 50 mg/kg Every 12 hours for 5 days To evaluate the effect of ticagrelor on inflammatory response and survival in endotoxemia, results showed that ticagrelor significantly reduced TNF-α levels and increased IL-10 levels, improving survival. JACC Basic Transl Sci. 2018 Aug 28;3(4):435-449
Mice Staphylococcus aureus infection model Oral 4 mg/kg Every 12 hours for 10 days Ticagrelor significantly increased platelet counts, reduced bacterial burden, and improved survival in infected mice Sci Transl Med. 2021 Mar 24;13(586):eabd6737.
Mice S. aureus infection model Oral 4 mg/kg Every 12 hours for 24 hours To evaluate the effect of Ticagrelor on platelet aggregation and survival in S. aureus-infected mice, results showed that Ticagrelor significantly reduced platelet aggregation and improved survival. J Clin Invest. 2023 Dec 1;133(23):e168450.
Mice ConA-induced immune hepatitis model Oral 15, 30, 60 mg/kg Once daily for 7 days To evaluate the protective effect of Ticagrelor on ConA-induced immune hepatitis, the results showed that Ticagrelor significantly reduced serum ALT and AST levels and alleviated pathological liver injury. Int J Biol Sci. 2023 Jul 9;19(11):3576-3594.
BALB/c mice 4T1 breast cancer tumor model Intravenous injection 10 mg/kg Every two days for 16 days To evaluate the anti-metastatic effect of CREKA-Lipo-T nanoparticles, results showed that CREKA-Lipo-T significantly reduced the number of lung metastatic foci. Theranostics. 2017 Feb 26;7(5):1062-1071.

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02482298 - Completed - -
NCT02482298 Sickle Cell Disease Phase 2 Completed - United States, Florida ... More >> Research Site Miami, Florida, United States, 33136 United States, Maryland Research Site Bethesda, Maryland, United States, 20817 United States, South Carolina Research Site Charleston, South Carolina, United States, 29425 Egypt Research Site Alexandria, Egypt, 21131 Research Site Cairo, Egypt, 11566 Research Site Cairo, Egypt France Research Site Bordeaux Cedex, France, 33076 Research Site Strasbourg, France, 67091 Italy Research Site Verona, Italy, 37134 Kenya Research Site Kisian, Kenya, 40100 Research Site Kisumu, Kenya, 40100 Research Site Nairobi, Kenya, 00100 Lebanon Research Site Beirut, Lebanon, 1107 2020 Research Site Beirut, Lebanon, 113-6044 Turkey Research Site Adana, Turkey, 01130 Research Site Mersin, Turkey, 33079 Research Site Van, Turkey, 65080 United Kingdom Research Site Harrow, United Kingdom, HA1 3UJ Research Site London, United Kingdom, E1 1BB Research Site London, United Kingdom, E9 6SR Less <<
NCT03129867 Acute Coronary Syndrome COMPLETED 2020-12-31 -
NCT02403830 - Completed - -
NCT02436577 Bioequivalence ... More >> Healthy Japanese Subjects Pharmacokinetics Less << Phase 1 Completed - United Kingdom ... More >> Research Site Harrow, United Kingdom Less <<
NCT01575795 ST-elevation Myocardial Infarc... More >>tion Less << Phase 4 Completed - Greece ... More >> Cardiology Department Patras University Hospital Rio, Achaia, Greece, 26500 Less <<
NCT02507323 Cardiovascular Disease Phase 2 Withdrawn(collaborator withdre... More >>w the study) Less << November 2017 United States, Texas ... More >> Baylor-St. Lukes Medical Center Houston, Texas, United States, 77030 Houston Methodist Hospital Houston, Texas, United States, 77030 Memorial Hermann Hospital Houston, Texas, United States, 77030 Less <<
NCT02052635 Non-ST Elevation Acute Coronar... More >>y Syndrome Less << Phase 4 Terminated(Patient recruitment... More >> challenges, low enrolment, and a forecasted inability to complete the study in an acceptable timeframe) Less << - United States, Florida ... More >> Research Site Jacksonville, Florida, United States Research Site Lake Mary, Florida, United States United States, Georgia Research Site Macon, Georgia, United States United States, Oklahoma Research Site Oklahoma City, Oklahoma, United States United States, Pennsylvania Research Site Hershey, Pennsylvania, United States Research Site Philadelphia, Pennsylvania, United States Research Site Pittsburgh, Pennsylvania, United States United States, South Dakota Research Site Rapid City, South Dakota, United States Less <<
NCT02052635 - Terminated(Patient recruitment... More >> challenges, low enrolment, and a forecasted inability to complete the study in an acceptable timeframe) Less << - -
NCT02071212 Coronary Artery Disease PHASE2 COMPLETED 2025-06-18 Ippokratio Hospital, Athens, G... More >>reece Less <<
NCT03126695 Sickle Cell Disease Phase 1 Completed - Germany ... More >> Research Site Berlin, Germany, 14050 Less <<
NCT02270242 Cardiovascular Disease ... More >> Interventional Cardiology Less << Phase 4 Active, not recruiting August 2019 United States, New York ... More >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 Less <<
NCT02436577 - Completed - -
NCT01852175 - Completed - -
NCT02403830 Coronary Artery Disease Phase 4 Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT02513004 Coronary Disease Phase 4 Recruiting April 2017 China, Beijing ... More >> Fuwai hospital Recruiting Beijing, Beijing, China Contact: Yongjian Wu, Doctor    008618613819658    nankedoudou@126.com Less <<
NCT03613857 - Completed - Egypt ... More >> Faculty of pharmacy Cairo university Cairo, Egypt, 01234567 Less <<
NCT01852175 Coronary Artery Disease Not Applicable Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT02075125 ST-Segment Elevation Myocardia... More >>l Infarction Less << Phase 3 Terminated(Enrolling participa... More >>nts has halted prematurely and will not resume) Less << - Korea, Republic of ... More >> DongA University Hospital Busan, Korea, Republic of, 602-715 Less <<
NCT02214121 - Completed - -
NCT01894789 Coronary Artery Disease Phase 2 Phase 3 Completed - Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y 4W7 Less <<
NCT02214121 Investigation of Platelet Aggr... More >>egation in Paediatric Patients With Sickle Cell Disease Less << Phase 2 Completed - United States, California ... More >> Research Site Orange, California, United States, 92868 United States, Illinois Research Site Chicago, Illinois, United States, 60612 United States, Michigan Research Site Detroit, Michigan, United States, 48201 United States, Pennsylvania Research Site Hershey, Pennsylvania, United States, 17022 Research Site Philadelphia, Pennsylvania, United States, 19104 United States, South Carolina Research Site Charleston, South Carolina, United States, 29425 Canada, Ontario Research Site Toronto, Ontario, Canada, M5G 1X8 Kenya Research Site Kisian, Kenya, 100 Research Site Nairobi, Kenya Lebanon Research Site Beirut, Lebanon, 1107 2020 Research Site Beirut, Lebanon, 113-6044 Research Site Tripoli, Lebanon, 1434 South Africa Research Site Parow, South Africa, 7500 Research Site Rondebosch, South Africa, 7700 United Kingdom Research Site Cardiff, United Kingdom, CF4 4XN Research Site London, United Kingdom, E1 1BB Research Site London, United Kingdom, SE1 7EH Research Site Manchester, United Kingdom, M13 9PT Less <<
NCT03614832 Platelet Reactivity Phase 4 Recruiting October 1, 2019 China, Heilongjiang ... More >> the first affiliated hospital of Harbin medical university Recruiting Harbin, Heilongjiang, China, 150001 Contact: Yue Li, PhD Less <<
NCT03381755 Acute Coronary Syndrome Phase 4 Recruiting December 14, 2020 China, Beijing ... More >> Thromboela-Stogram Recruiting Beijing, Beijing, China, 100001 Contact: Liu Yang, MM    86-010-801231171 Less <<
NCT02075125 - Terminated(Enrolling participa... More >>nts has halted prematurely and will not resume) Less << - -
NCT01373411 Coronary Artery Disease Phase 4 Completed - Canada, British Columbia ... More >> Vancouver General Hospital Vancouver, British Columbia, Canada Less <<
NCT02053909 Saphenous Vein Graft Disease Phase 4 Recruiting August 2023 United States, Florida ... More >> Boca Raton Regional Hospital Recruiting Boca Raton, Florida, United States, 33486 Contact: Alexander Kulik, MD MPH       alex_kulik@yahoo.com    Principal Investigator: Alexander Kulik, MD MPH          Canada, Ontario University of Ottawa Heart Institute Recruiting Ottawa, Ontario, Canada Contact: Marc Ruel, MD MPH       mruel@ottawaheart.ca    Principal Investigator: Marc Ruel, MD MPH Less <<
NCT02808767 Myocardial Infarction ... More >> Angioplasty, Balloon, Coronary Platelet Aggregation Inhibitors Less << Phase 4 Completed - Czechia ... More >> Faculty Hospital Kralovske Vinohrady Prague, Czechia, 10034 Less <<
NCT02626169 Atherosclerosis Phase 4 Recruiting July 2018 United States, Texas ... More >> Baylor Clinic Recruiting Houston, Texas, United States, 77030 Contact: Yochai Birnbaum, MD    713-798-2735    ybirnbau@bcm.edu    Baylor College of Medicine Recruiting Houston, Texas, United States, 77030 Contact: Yochai Birnbaum, MD    713-798-2735    ybirnbau@bcm.edu Less <<
NCT02352402 Coronary Artery Disease ... More >> Stable Angina Acute Coronary Syndrome Less << Phase 3 Recruiting December 2020 Netherlands ... More >> St Antonius Hospital Recruiting Nieuwegein, Utrecht, Netherlands, 3435CM Contact: J.M. ten Berg, MD, PhD    0031-30-6099111    berg03@antoniusziekenhuis.nl    Contact: J.W. van Werkum, MD, PhD    0031-30-6099111    w.van.werkum@antoniusziekenhuis.nl    Sub-Investigator: D. Taubert, MD, PharmD          Sub-Investigator: H.J. Bouman, MSc Less <<
NCT03331484 Atrial Fibrillation ... More >> Acute Coronary Syndrome Less << Phase 3 Recruiting December 15, 2021 Canada, Ontario ... More >> University of Ottawa Heart Institute Recruiting Ottawa, Ontario, Canada, K1Y 4W7 Contact: Michel Le May, MD    613-696-7297    mlemay@ottawaheart.ca    Contact: Savannah Harrison-Hayman, B.A. (Hons)    613-696-7297    sharrison-hayman@ottawaheart.ca    Principal Investigator: Michel Le May, MD Less <<
NCT01511471 Platelet Reactivity PHASE3 COMPLETED 2025-02-12 Agios Andreas General Hospital... More >>, Nephrology Department, Patras, Achaia, 26500, Greece|Cardiology Department Patras University Hospital, Rio, Achaia, 26500, Greece Less <<
NCT01226602 Blood Flow Speed ... More >> Coronary Flow Velocity Less << Phase 1 Completed - Sweden ... More >> Research Site Uppsala, Sweden Less <<
NCT02217878 ST-segment Elevation Myocardia... More >>l Infarction Non-ST-segment Elevation Myocardial Infarction VA Drug Interactions Less << Phase 4 Completed - Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Bydgoszcz, Kujawsko-pomorskie, Poland, 85-094 Less <<
NCT02989558 Aortic Valve Stenosis Phase 3 Recruiting December 2018 Greece ... More >> 1st Department of Cardiology, Hippokration Hospital Recruiting Athens, Greece Contact: EMMANOUIL VAVOURANAKIS, Ass. Prof    00306945791700    vavouran@otenet.gr    Contact: KONSTANTINOS KALOGERAS, MD    00306932515977    kalogerask@yahoo.gr Less <<
NCT02217878 - Completed - -
NCT01961856 Platelet Reactivity Phase 3 Completed - Greece ... More >> Patras University Hospital Patras, Achaia, Greece, 26500 Less <<
NCT01852214 - Completed - -
NCT02514642 Coronary Artery Disease Phase 4 Unknown November 2015 United States, California ... More >> VerifyNow Recruiting San Diego, California, United States, 92101-92117 Contact: Meijiao He, Master    518-393-2200    customerservice@accriva.com Less <<
NCT01852214 Diabetes Mellitus ... More >> Coronary Artery Disease Less << Not Applicable Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT02383771 Coronary Artery Disease Phase 4 Completed - China, Jiangsu ... More >> First Affiliated Hospital of Nanjing Medical University Nanjing, Jiangsu, China, 210029 Less <<
NCT02219412 Coronary Heart Disease Phase 4 Completed - China ... More >> Peking University First Hospital Beijing, China, 100034 Less <<
NCT02022748 - Completed - -
NCT02022748 Kidney Failure, Chronic Phase 1 Completed - United States, Colorado ... More >> Research Site Lakewood, Colorado, United States, 80228 United States, Minnesota Research Site Minneapolis, Minnesota, United States, 55404 Less <<
NCT03078465 Coronary Artery Disease Phase 3 Recruiting May 30, 2021 China, Jiangsu ... More >> Nanjing First Hospital Recruiting Nanjing, Jiangsu, China, 210006 Contact: Shaoliang Chen, MD    +86 13605157029    chmengx@126.com    Principal Investigator: Shaoliang Chen, MD          Sub-Investigator: Junjie Zhang, MD PHD Less <<
NCT03182855 Acute Coronary Syndrome ... More >> Myocardial Infarction STEMI - ST Elevation Myocardial Infarction Less << Phase 4 Not yet recruiting August 1, 2019 Denmark ... More >> Aarhus University Hospital Not yet recruiting Aarhus, Denmark, 8200 Contact: Jacob Thorsted Sorensen, MD, PhD    +4540143563    jacsoe@rm.dk    Contact: Steen D Kristensen, MD, DMSc    +4530922336    stekrist@rm.dk Less <<
NCT03679091 Platelet Reactivity Phase 4 Recruiting August 29, 2019 China, California ... More >> VerifyNow Recruiting Harbin, California, China, 150001 Contact: Meijiao He, doctor    518-393-2200    customerservice@accriva.com    Contact: Jing Shi, Professor    86-451-85555672    yidashijing@163.com Less <<
NCT03615924 Sickle Cell Disease Phase 3 Recruiting November 9, 2020 -
NCT02065479 Coronary Artery Disease Phase 4 Recruiting January 2020 United States, Florida ... More >> University of Florida Recruiting Jacksonville, Florida, United States, 32209 Contact: Dominick Angiolillo       dominick.angiolillo@jax.ufl.edu    Principal Investigator: Dominick J Angiolillo, MD, PhD Less <<
NCT02422888 Myocardial Infarction Phase 4 Active, not recruiting October 2019 Netherlands ... More >> VU University Medical Center Amsterdam, Noord-Holland, Netherlands, 1081 HV Less <<
NCT02163954 Chronic Kidney Disease Phase 3 Completed - Korea, Republic of ... More >> Kyung Hee University Hospital Seoul, Korea, Republic of, 130-702 Less <<
NCT02925923 Acute Coronary Syndrome ... More >> Angina, Unstable Less << Phase 2 Recruiting December 2023 United States, Alabama ... More >> University of Alabama Recruiting Birmingham, Alabama, United States, 35294 Principal Investigator: Massoud Leesar, MD Less <<
NCT01998399 Community Acquired Pneumonia, ... More >>Severe Less << Phase 2 Terminated(poor enrollment, un... More >>able to meet recruitment goals) Less << - -
NCT01998399 - Terminated(poor enrollment, un... More >>able to meet recruitment goals) Less << - -
NCT02291419 Myocardial Injury Phase 4 Terminated(Enrollment expectat... More >>ions were not met) Less << - -
NCT02298088 Acute ST Segment Elevation Myo... More >>cardial Infarction Thrombolysis in Myocardial Infarction Flow Less << Phase 3 Active, not recruiting December 2018 -
NCT03354429 Acute Ischaemic Stroke ... More >> Transient Ischaemic Attack Less << Phase 3 Recruiting December 16, 2019 -
NCT01731041 - Completed - -
NCT01731041 Coronary Artery Disease Not Applicable Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT02291419 - Terminated(Enrollment expectat... More >>ions were not met) Less << - -
NCT02046486 ST Elevation Myocardial Infarc... More >>tion Less << Phase 4 Completed - Greece ... More >> Patras University Hospital Department of Cardiology Patras, Achaia, Greece, 26500 Less <<
NCT02430493 - Completed - China ... More >> Research Site Beijing, China Research Site Changchun, China Research Site Changsha, China Research Site Dalian, China Research Site Guangzhou, China Research Site Huai'an, China Research Site Jinan, China Research Site Nanjing, China Research Site Shanghai, China Research Site Shenzhen, China Research Site Suqian, China Research Site Tai'an, China Research Site Wuhan, China Research Site Xuzhou, China Research Site Zhengzhou, China Less <<
NCT03092076 Healthy PHASE1 COMPLETED 2016-06-16 -
NCT01991795 Diabetes Mellitus, Type 2 Phase 3 Active, not recruiting December 28, 2018 -
NCT02578537 Non ST Segment Elevation Acute... More >> Coronary Syndrome Chronic Kidney Disease Less << Phase 4 Unknown July 2016 China, Liaoning ... More >> Shenyang Northern Hospital Recruiting Shenyang, Liaoning, China, 110016 Contact: Yaling Han, MD,PHD    86-024-28856123    hanyaling@263.net    Contact: Yi Li, MD    86-024-28897309    doctorliyi@126.com Less <<
NCT02048085 Acute ST Segment Elevation Myo... More >>cardial Infarction Acute Coronary Syndrome Less << Phase 4 Withdrawn(unable to get study ... More >>up and enrolling) Less << March 2018 United States, Arkansas ... More >> Medical Center of South Arkansas El Dorado, Arkansas, United States, 71730 Less <<
NCT03454841 Acute Myocardial Infarction Phase 4 Recruiting December 31, 2018 Poland ... More >> Department of Cardiology, Wrocław Medical University Recruiting Wrocław, Dolnośląskie, Poland, 50-556 Contact: Wiktor Kuliczkowski, MD, PhD    +48717842240    wkuliczkowski@wp.pl    Principal Investigator: Wiktor Kuliczkowski, MD, PhD          Sub-Investigator: Magdalena Cielecka-Prynda, MD          Department of Cardiology, Dr. A. Jurasz University Hospital, Collegium Medicum, Nicolaus Copernicus University Recruiting Bydgoszcz, Kujawsko-pomorskie, Poland, 85-094 Contact: Piotr Adamski, MD, PhD    +48525854023    piotr.adamski@wp.eu    Principal Investigator: Aldona Kubica, PhD          Sub-Investigator: Piotr Adamski, MD, PhD          Sub-Investigator: Małgorzata Ostrowska, MD, PhD Less <<
NCT02402400 Acute Coronary Syndromes ... More >> Non ST Elevation Myocardial Infarction Less << Phase 4 Completed - Israel ... More >> Sheba Medical center Ramat Gan, Israel Less <<
NCT01706510 Coronary Artery Disease Phase 4 Completed - United States, South Dakota ... More >> Regional Heart Doctors/Black Hills Cardiovascular Research Rapid City, South Dakota, United States, 57701 Less <<
NCT03387826 Myocardial Infarction ... More >> Diabetes Mellitus Coronary Artery Disease Renal Disease Less << Phase 4 Recruiting January 2019 Greece ... More >> Attikon University Hospital Recruiting Chaidari, Greece, 12462 Contact: DIMITRIOS ALEXOPOULOS, MD    30-6944314398    dalex@med.uoa.gr    Contact: Danai Sfantou, MD    6975023693    danaes8@yahoo.gr Less <<
NCT02086903 Pharmacodynamics Phase 3 Completed - Korea, Republic of ... More >> Dong A University Hospital Busan, Korea, Republic of, 602-715 Less <<
NCT02505399 Atherosclerosis Phase 4 Recruiting May 2018 France ... More >> Clinique Pasteur Recruiting Toulouse, Haute-Garonne, France, 31000 Contact: Bruno FAHRAT, MD          Fédération de Cardiologie CHU TOULOUSE Recruiting Toulouse, Haute-Garonne, France, 31059 Contact: Didier CARRIER, PHD    561 323 324 ext 33    carrie.d@chu-toulouse.fr    Hospices civils de Lyon Recruiting Lyon, France, 69000 Contact: Gilles RIOUFOL, PHD          University Hospital Recruiting Nîmes, France, 30000 Contact: Guillaume CAYLA, MD Less <<
NCT01876797 Healthy Phase 1 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Less <<
NCT02081443 - Completed - -
NCT02071966 Non ST Segment Elevation Acute... More >> Coronary Syndrome Less << Phase 4 Terminated(slow enrollment) November 2016 Italy ... More >> Policlinico "A.Gemelli" Rome, Italy, 00168 Less <<
NCT02121288 Peripheral Artery Disease ... More >> Vascular Disease Arterial Occlusion Disease Intermittent Claudication Ankle Brachial Index (0.9 or Less) Less << Phase 4 Withdrawn February 2016 -
NCT01766466 Coronary Artery Disease Phase 2 Completed - United States, Vermont ... More >> Fletcher Allen Health Care Burlington, Vermont, United States, 05401 Less <<
NCT01962428 Non ST Segment Elevation Acute... More >> Coronary Syndrome Less << Phase 4 Completed - China, Beijing ... More >> General Hospital of Chinese People's Armed Police Forces Beijing, Beijing, China, 100039 China General Hospital of Chinese People's Armed Police Forces Beijing, China Less <<
NCT01766466 - Completed - -
NCT01962428 - Completed - -
NCT02725099 Acute Coronary Syndromes ... More >> ST Elevation Myocardial Infarction Less << Phase 4 Completed - Israel ... More >> Sheba Medical center Ramat Gan, Israel Less <<
NCT01898442 - Completed - -
NCT02016170 Coronary Artery Disease ... More >> Acute Coronary Syndrome Less << Not Applicable Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT02081443 Coronary Artery Disease Not Applicable Completed - United States, Florida ... More >> Dominick Angiolillo Jacksonville, Florida, United States, 32209 Less <<
NCT03620760 Unstable Angina Pectoris ... More >> Coronary Stent Implantation Less << Phase 4 Recruiting December 31, 2020 China, Beijing ... More >> Xiaofan Wu Recruiting Beijing, Beijing, China, 100029 Contact: Xiaofan Wu, Master Less <<
NCT01919723 Acute Coronary Syndrome Phase 2 Completed - United States, Alabama ... More >> University of Alabama Birmingham, Alabama, United States, 35294 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 Less <<
NCT01898442 Coronary Artery Disease Phase 2 Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT01919723 - Completed - -
NCT02091921 Critical Limb Ischemia PHASE1|PHASE2 COMPLETED 2016-11-30 University of Southern Califor... More >>nia, Los Angeles, California, 90033, United States Less <<
NCT01992523 Acute Coronary Syndrome ... More >> Adverse Reaction to Antiplatelet Agent Less << Phase 3 Completed - Greece ... More >> Department of Cardiology, Patras University Hospital Patras, Greece Italy Careggi Hospital Florence, Italy Less <<
NCT02943369 STEMI Phase 4 Completed - Greece ... More >> Attikon University Hospital Athens, Attika, Greece, 12462 Less <<
NCT01992523 - Completed - -
NCT02323971 Coronary Artery Disease UNKNOWN 2025-12-18 Hospital Universitario Virgen ... More >>de la Arrixaca, Murcia, 30120, Spain Less <<
NCT02539160 Coronary Artery Disease ... More >> Diabetes Mellitus Less << Phase 4 Recruiting March 2019 United States, Florida ... More >> University of Florida Recruiting Jacksonville, Florida, United States, 32209 Contact: Dominick Angiolillo       dominick.angiolillo@jax.ufl.edu Less <<
NCT02469740 Myocardial Ischemia ... More >> Coronary Artery Disease Endothelial Dysfunction Less << Phase 4 Completed - Ireland ... More >> University Hospital Limerick Dooradoyle, Limerick, Ireland Less <<
NCT02435563 Healthy Phase 2 Completed - Switzerland ... More >> Centre de Recherche Clinique, HUG, Rue Gabrielle Perret-Gentil 4 Genève, Switzerland, 1211 Less <<
NCT02016170 - Completed - -
NCT03005704 Ticagrelor As... More >>pirin Platelet Dysfunction Due to Drugs Transfusion Less << Not Applicable Recruiting January 2018 Canada, Ontario ... More >> Population Health Research Institute Recruiting Hamilton, Ontario, Canada, L9L 2X2 Contact: Paul Kruger, MB BS    9059230285    paul.kruger@phri.ca Less <<
NCT02580149 Ischemia Phase 4 Completed - Austria ... More >> Medical University of Vienna, Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT02064985 Stable Coronary Heart Disease ... More >>(CHD) Less << Phase 4 Completed - China ... More >> Research Site Beijing, China Less <<
NCT03658005 - Not yet recruiting January 1, 2019 -
NCT02602444 - Completed - Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Bydgoszcz, Kujawsko-pomorskie, Poland, 85-094 Less <<
NCT02612116 Unstable Angina Pectoris Phase 4 Completed - Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Bydgoszcz, Kujawsko-Pomorskie, Poland, 85-094 Less <<
NCT03489863 Coronary Artery Disease Phase 4 Recruiting August 2019 United States, Florida ... More >> University of Florida Recruiting Jacksonville, Florida, United States, 32209 Contact: Dominick J Angiolillo, MD, PhD       dominick.angiolillo@jax.ufl.edu    Principal Investigator: Dominick J Angiolillo, MD, PhD Less <<
NCT02406911 Chronic Kidney Disease PHASE3 UNKNOWN 2025-08-15 Kyung Hee University Hospital,... More >> Seoul, 130-872, Korea, Republic of Less <<
NCT02518464 Migraine Head... More >>ache Migraine Headache Less << Phase 4 Active, not recruiting October 2017 United States, New York ... More >> Columbia University Medical Center New York, New York, United States, 10032 Less <<
NCT02284048 Microvascular Angina Phase 4 Unknown November 2017 -
NCT02282332 Coronary Artery Disease PHASE4 COMPLETED 2025-04-16 -
NCT03708588 Percutaneous Coronary Interven... More >>tion Less << Phase 4 Recruiting July 31, 2020 United States, Wisconsin ... More >> Aurora Health Care, St. Luke's Medical Center Recruiting Milwaukee, Wisconsin, United States, 53215 Contact: Wendy Dunaj    414-649-3512    wendy.dunaj@aurora.org    Principal Investigator: Thomas Wilson, MD Less <<
NCT03251859 Myocardial Infarction Phase 3 Completed - Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Bydgoszcz, Kujawsko-pomorskie, Poland, 85-094 Less <<
NCT02939235 Unstable Angina Pectoris Phase 4 Recruiting September 2017 Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Recruiting Bydgoszcz, Kujawsko-Pomorskie, Poland, 85-094 Contact: Piotr Niezgoda, M.D.    +48525854023    piotr.niezg@gmail.com Less <<
NCT02265068 Acute Coronary Syndrome (ACS) COMPLETED 2025-12-16 Zentralklinik Bad Berka GmbH, ... More >>Bad Berka, 99437, Germany|Vivantes-Klinikum Neuk?lln, Berlin, 12351, Germany|Klinikum Hildesheim GmbH, Hildesheim, 31135, Germany|Krankenhaus Landshut-Achdorf, Landshut, 84036, Germany|Klinikum Ludwigshafen, Ludwigshafen, Germany|Klinikum-Wetzlar Braunsfeld, Wetzlar, 35578, Germany Less <<
NCT02064985 - Completed - -
NCT03492931 Sickle Cell Disease PHASE1 COMPLETED 2019-05-07 Research Site, Edegem, 2650, B... More >>elgium|Research Site, Genova, 16100, Italy|Research Site, Kisumu, 40100, Kenya|Research Site, Nairobi, 00100, Kenya|Research Site, Beirut, 11-0236, Lebanon|Research Site, Tripoli, 1434, Lebanon|Research Site, Madrid, 28007, Spain|Research Site, London, SE1 7EH, United Kingdom Less <<
NCT02939248 Unstable Angina Pectoris Phase 4 Recruiting September 2017 Poland ... More >> Cardiology Department, Dr. A. Jurasz University Hospital Recruiting Bydgoszcz, Kujawsko-Pomorskie, Poland, 85-094 Contact: Piotr Niezgoda, M.D.    +48525854023    piotr.niezg@gmail.com Less <<
NCT03577652 Coronary Artery Disease|Ticagr... More >>elor Less << COMPLETED 2018-01-10 General Hospital of Shenyang M... More >>ilitary Region, Shenyang, Liaoning, 110016, China Less <<
NCT02335099 End Stage Renal Disease ... More >> Vascular Access Patency Less << Phase 1 Phase 2 Recruiting June 2018 United States, Virginia ... More >> University of Virginia - Hospital West Kidney Center Dialysis Recruiting Charlottesville, Virginia, United States, 22908 Contact: Emaad M Abdel-Rahman, MD    434-982-3198    ea6n@virginia.edu    Contact: Sharon F Johnson, BA, CCRC    434-982-3198    sfj8n@virginia.edu    Principal Investigator: Emaad M Abdel-Rahman, MD, PhD          Sub-Investigator: Warren K Bolton, MD          Sub-Investigator: Rasheed A Balogun, MD          Sub-Investigator: Jane Bopp, RN, FNP          Sub-Investigator: Sharon F Johnson, BA, CCRC Less <<
NCT02292277 Myocardial Infarction COMPLETED 2025-01-16 S?dersjukhuset, Stockholm, 118... More >> 83, Sweden Less <<
NCT03437044 Diabetes Mellitus, Type 2 ... More >> Coronary Artery Disease Less << Phase 4 Recruiting July 2019 United States, Florida ... More >> University of Florida Recruiting Jacksonville, Florida, United States, 32209 Contact: Dominick J Angiolillo, MD, PhD       dominick.angiolillo@jax.ufl.edu    Principal Investigator: Dominick J Angiolillo, MD, PhD Less <<
NCT03039205 Platelet Aggregation ... More >> Adenosine Coronary Artery Disease Kidney Dysfunction Antiplatelet Therapy Less << Phase 2 Recruiting December 15, 2018 Brazil ... More >> Instituto do Coração (InCor) - Hospital das Clínicas da FMUSP Recruiting Sao Paulo, Brazil Contact: André Franci, M.D.    55 11 2661-5850 Less <<
NCT02341729 Acute Coronary Syndrome Phase 4 Unknown January 2017 Belgium ... More >> Intensive Care Unit, Ghent University Hospital Not yet recruiting Ghent, Belgium, 9000 Contact: Harlinde Peperstraete, MD    +3293325185    harlinde.peperstraete@ugent.be Less <<
NCT01510171 ST-segment Elevation Myocardia... More >>l Infarction Less << Phase 4 Completed - Italy ... More >> Careggi Hospital Florence, Italy, 50134 Less <<
NCT02627521 Coronary Artery Disease Phase 4 Recruiting August 2017 Canada, Ontario ... More >> St. Michael's hospital Recruiting Toronto, Ontario, Canada, M5B 1W8 Contact: Asim Cheema, MD    416-864-5739    cheemaA@smh.ca Less <<
NCT02581280 - Unknown December 2016 Korea, Republic of ... More >> Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 03722 Contact: Jin Wi, MD    82-2-2228-8460    caesar@yuhs.ac Less <<
NCT03224923 Stable Coronary Syndrome ... More >> Percutaneous Coronary Intervention Antiplatelet Therapy Ticagrelor Less << Phase 4 Terminated(Competing study to ... More >>be started in November 2018) Less << - Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y4W7 Less <<
NCT02376283 Heart Attack Phase 4 Unknown December 2017 United Kingdom ... More >> The Royal Wolverhampton NHS Trust Recruiting Wolverhampton, West Midlands, United Kingdom, WV10 0QP Contact: Vincent Amoah          Contact: James Cotton Less <<
NCT03212287 - Recruiting June 28, 2024 Japan ... More >> Research Site Not yet recruiting Chiba, D5133n00007, Japan, D5133N00007 Research Site Active, not recruiting Fukuoka, D5133n00007, Japan, D5133N00007 Research Site Recruiting Fukuoka, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Fukushima, D5133n00007, Japan, D5133N00007 Research Site Withdrawn Gifu, D5133n00007, Japan, D5133N00007 Research Site Recruiting Gunma, D5133n00007, Japan, D5133N00007 Research Site Recruiting Hokkaido, D5133n00007, Japan, D5133N00007 Research Site Active, not recruiting Hokkaido, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Hokkaido, D5133n00007, Japan, D5133N00007 Research Site Recruiting Hyogo, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Hyogo, D5133n00007, Japan, D5133N00007 Research Site Recruiting Kagoshima, D5133n00007, Japan, D5133N00007 Research Site Recruiting Kanagawa, D5133n00007, Japan, D5133N00007 Research Site Active, not recruiting Kanagawa, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Kanagawa, D5133n00007, Japan, D5133N00007 Research Site Recruiting Kochi, D5133n00007, Japan, D5133N00007 Research Site Recruiting Kumamoto, D5133n00007, Japan, D5133N00007 Research Site Recruiting Kyoto, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Mie, D5133n00007, Japan, D5133N00007 Research Site Recruiting Miyagi, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Nagano, D5133n00007, Japan, D5133N00007 Research Site Recruiting Nara, D5133n00007, Japan, D5133N00007 Research Site Recruiting Okayama, D5133n00007, Japan, D5133N00007 Research Site Recruiting Okinawa, D5133n00007, Japan, D5133N00007 Research Site Recruiting Osaka, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Osaka, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Saitama, D5133n00007, Japan, D5133N00007 Research Site Recruiting Saitama, D5133n00007, Japan, D5133N00007 Research Site Recruiting Shiga, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Shiga, D5133n00007, Japan, D5133N00007 Research Site Recruiting Shizuoka, D5133n00007, Japan, D5133N00007 Research Site Active, not recruiting Tochigi, D5133n00007, Japan, D5133N00007 Research Site Recruiting Tochigi, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Tokushima, D5133n00007, Japan, D5133N00007 Research Site Recruiting Tokyo, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Tokyo, D5133n00007, Japan, D5133N00007 Research Site Recruiting Wakayama, D5133n00007, Japan, D5133N00007 Research Site Not yet recruiting Wakayama, D5133n00007, Japan, D5133N00007 Less <<
NCT02110303 Coronary Artery Disease Phase 2 Phase 3 Active, not recruiting May 2018 United Kingdom ... More >> Edinburgh Heart Centre Edinburgh, Lothian, United Kingdom, EH16 4SA Less <<
NCT01805570 Myocardial Infarction Phase 4 Completed - Italy ... More >> Careggi Hospital Florence, Italy Less <<
NCT02175875 - Completed - Denmark ... More >> Rigshospitalet Copenhagen O, Denmark, 2100 Less <<
NCT01793597 - Completed - United States, Vermont ... More >> University of Vermont Medical Center Burlington, Vermont, United States, 05401 Less <<
NCT03330223 - Recruiting September 1, 2019 China, Jiangsu ... More >> First Affiliated Hospital of Nanjing Medical University Recruiting Nanjing, Jiangsu, China, 210029 Contact: Fuming Zhang, M.D.    +86-25-83718836 ext 6360    jsphkj@163.com    Contact: Yi Chai, M.D.    +86-25-83718836 ext 6360    jsphkj@163.com    Principal Investigator: chunjian Li, Ph.D          Sub-Investigator: yuansheng fan, Master          Sub-Investigator: xiaoxuan Zhou, Master Less <<
NCT03487406 Chronic Obstructive Pulmonary ... More >>Disease (COPD) Less << Phase 2 Completed - United Kingdom ... More >> Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne, United Kingdom, NE7 7DN Less <<
NCT03400267 STEMI STEMI -... More >> ST Elevation Myocardial Infarction Less << Phase 4 Recruiting February 28, 2019 Netherlands ... More >> Isala clinics Recruiting Zwolle, Netherlands Contact: R Hermanides, MD/PHD Less <<
NCT02201771 Coronary Artery Bypass ... More >> Antiplatelet Agents Less << Phase 4 Completed - China, Henan ... More >> Henan Provincial People's Hospital Zhengzhou, Henan, China China, Jiangsu Jiangsu Province Hospital Nanjing, Jiangsu, China Nan Jing First Hospital Nanjing, Jiangsu, China China, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China, 200025 Xinhua Hospital, Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China, 200092 Changhai Hospital of Shanghai Shanghai, Shanghai, China, 200433 Less <<
NCT03671941 Acute Coronary Syndrome Phase 1 Completed - Korea, Republic of ... More >> Chonbuk National University Hospital Jeonju, Korea, Republic of Less <<
NCT02198053 - Unknown December 2015 China ... More >> Anzhen Hospital Beijing, China, 100029 Less <<
NCT03492385 Healthy Phase 1 Completed - United States, Texas ... More >> PPD Austin, Texas, United States, 78744 Less <<
NCT02311088 Dyspnea Phase 2 Terminated(Too low enrolment r... More >>ate) Less << - Sweden ... More >> Dept of Cardiology, Mälarsjukhuset hospital Eskilstuna, Sweden Dept. of Cardiology, Falu hospital Falun, Sweden Dept of Cardiology, Östra hospital Gothenburg, Sweden Dept of Cardiology, Gävle Hospital Gävle, Sweden Dept. of Cardiology, Linköping University Hospital Linköping, Sweden Dept of Cardiology, Skåne University Hospital Lund, Sweden Dept. of Cardiology, Danderyd hospital Stockholm, Sweden Dept of Cardiology, Umeå University Hospital Umeå, Sweden Dept of Cardiology, Uppsala University Hospital Uppsala, Sweden, SE-75185 Less <<
NCT02931045 Myocardial Infarction Phase 4 Recruiting December 2019 Netherlands ... More >> Laboratory of Experimental Clinical Chemistry, Academic Medical Centre of the University of Amsterdam Active, not recruiting Amsterdam, Netherlands Poland 1st Chair and Department of Cardiology, Medical University of Warsaw Recruiting Warsaw, Poland Contact: Aleksandra Gasecka, MD       aleksandra.gasecka@wum.edu.pl    Contact: Krzysztof J. Filipiak, Prof., MD Less <<
NCT01744288 Inhibition on Platelet Aggrega... More >>tion Less << Phase 1 Completed - United States, Kansas ... More >> Research Site Overland Park, Kansas, United States Less <<
NCT00738842 Gout Coronary... More >> Artery Disease Less << Phase 1 Completed - -
NCT02302508 Diabetes Phase 4 Not yet recruiting December 2021 Canada, Quebec ... More >> Centre hospitalier de l'Université de Montréal (CHUM) Montreal, Quebec, Canada, H2X0A9 Less <<
NCT01823185 Coronary Artery Disease ... More >> Myocardial Infarction Heart Disease Vascular Disease Angina Pectoris Cardiovascular Disease Ischemia Infarction Embolism Thrombosis Chest Pain Less << Phase 4 Unknown March 2016 Saudi Arabia ... More >> Prince Sultan Cardiac center Recruiting Al-Hasa, Saudi Arabia, 31982 Sub-Investigator: Abdullah Alabdulgader, MD          King Fahd University Hospital Recruiting Al-Khobar, Saudi Arabia, 31441 Principal Investigator: Abdullah M Al-Rubaish, MD          Sub-Investigator: Fahd A Al-Muhanna, MD          Sub-Investigator: Emmanuel Larbi, MD, PhD          Sub-Investigator: Abdullah Al-Shehri, MD          Sub-Investigator: Akram Al-Khadra, MD          Sub-Investigator: Amein Al-Ali, PhD          Sub-Investigator: Mohammed Al-Mansory, MD          Saud Al-Babtain Cardiac Center Recruiting Dammam, Saudi Arabia, 31463 Sub-Investigator: Hamid Al-Omran, MD          Sub-Investigator: Mustafa Al-Refaei, MD          Sub-Investigator: Najeeb Abdulhamid, MD          Sub-Investigator: Shukry Mirza, MD          Sub-Investigator: Yousef Alsabeet, MD          King Fahd Military Medical Complex Recruiting Dammam, Saudi Arabia, 31932 Sub-Investigator: Khalid Al-Fraiedi, MD Less <<
NCT03540459 - Recruiting September 30, 2018 France ... More >> Les Grands Prés Recruiting Villeneuve Saint Denis, France, 77174 Contact: Philippe Meurin, MD    0674003218    philippemeurin@hotmail.com    Sub-Investigator: Helene Weber, MD Less <<
NCT01777516 - Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Less <<
NCT03649711 Chronic Kidney Diseases ... More >> Heart Attack Stroke, Ischemic Less << Phase 3 Recruiting June 30, 2021 United States, Arkansas ... More >> Central Arkansas Veterans Affairs Hospital Not yet recruiting Little Rock, Arkansas, United States, 72205 Contact: Luis Juncos, MD    501-257-1000 ext 5877    luis.juncos@va.gov    Contact: Brandi Mojica, BA    5012571000 ext 5877    brandi.mojica@va.gov    University of Arkansas for Medical Sciences Recruiting Little Rock, Arkansas, United States, 72205 Contact: Jain Nishank, MD    501-686-5295    NJain2@uams.edu    Contact: Giuseppina Dusio, Ph D    501-6865301    gdusio@uams.edu Less <<
NCT03729401 Coronary Artery Disease ... More >> Myocardial Infarction Less << Phase 4 Not yet recruiting October 2021 -
NCT01626534 Acute Coronary Syndrome Phase 3 Completed - France ... More >> Assistance Publique Hopitaux de Marseille Marseille, France, 13354 Less <<
NCT02224066 Severe Aortic Valve Stenosis ... More >> Transcatheter Aortic Valve Implantation Transcatheter Aortic Valve Replacement Less << Phase 4 Completed - Spain ... More >> Hospital Clinic Universitari Bellvitge Hospitalet de Llobregat, Barcelona, Spain, 08907 Hospital Universitario Álvaro Cunqueiro Vigo, Pontevedra, Spain, 36312 Hospital Santa Creu i Sant Creu Barcelona, Spain, 08026 Hospital Virgen de las Nieves Granada, Spain, 18014 Hospital Universitario La Paz Madrid, Spain, 28046 Hospital Universitario Virgen de la Arrixaca Murcia, Spain, 30120 Hospital Universitario de Salamanca Salamanca, Spain, 37007 Less <<
NCT02817789 Aortic Valve Stenosis Phase 3 Unknown May 2018 France ... More >> CHRU de Lille Not yet recruiting Lille, France, 59037 Contact: Eric VANBELLE, Pr       eric.vanbelle2@chru-lille.fr    Contact: Bérénice MARCHANT       berenice.marchant@chru-lille.fr    Principal Investigator: Eric VANBELLE, Pr          APHM Recruiting Marseille, France, 13005 Contact: Thomas CUISSET, Pr       thomas.cuisset@.ap-hm.fr    Principal Investigator: Thomas CUISSET, Pr          CHRU de Nîmes Not yet recruiting Nîmes, France, 30029 Contact: Guillaume CAYLA, Pr       cayla.guillaume@gmail.com    Contact: Chrystel LEPERCHOIS-JACQUEY       leperchois.jacquey@gmail.com    Principal Investigator: Guillaume CAYLA, Pr          APHP Not yet recruiting Paris, France, 75013 Contact: Jean-Philippe COLLET, Pr       jean-philippe.collet@psl.aphp.fr    Contact: Benjamin BERTIN       benjamin.bertin-ext@aphp.fr    Principal Investigator: Jean-Philippe COLLET, Pr          CHU de Bordeaux Not yet recruiting Pessac, France, 33604 Contact: Lionel LEROUX, Dr       lionel.leroux@chu-bordeaux.fr    Contact: Cécile JORE       cecile.jore@chu-bordeaux.fr    Principal Investigator: Lionel LEROUX, Dr          Sub-Investigator: Marina DIJOS, Dr          Sub-Investigator: Stéphane LAFITTE, Pr          Sub-Investigator: Frédéric CASASSUS, Dr          Sub-Investigator: Benjamin SEGUY, Dr          Sub-Investigator: Julien PELTAN, Dr Less <<
NCT02942550 STEMI Morphin... More >>e Ticagrelor Methylnaltrexone Less << Phase 4 Completed - Sweden ... More >> Karolinska University Hospital Stockholm, Sweden Södersjukhuset (Stockholm South General Hospital) Stockholm, Sweden Less <<
NCT01812200 Atrial Fibrillation ... More >> Acute Coronary Syndrome Less << Phase 4 Completed - Austria ... More >> Medical University of Vienna; Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT00528411 Coronary Artery Disease Phase 2 Completed - United States, Louisiana ... More >> Research Site Baton Rouge, Louisiana, United States United States, Maryland Research Site Baltimore, Maryland, United States Research Site Towson, Maryland, United States United States, Ohio Research Site Cincinnati, Ohio, United States United States, Oklahoma Research Site Oklahoma City, Oklahoma, United States United States, Pennsylvania Research Site Philadelphia, Pennsylvania, United States United States, South Dakota Research Site Rapid City, South Dakota, United States United States, Texas Research Site Houston, Texas, United States United Kingdom Research Site Sheffield, United Kingdom Less <<
NCT02808039 - Unknown - Israel ... More >> Rabin Medical Center - Hsharon Campus Not yet recruiting Petach-Tikva, Israel, 49100 Contact: Guy Witberg, MD    9+972)528478828    vitberguy@gmail.com    Contact: Eli Lev, MD    9+972)504065490    elev@tmhs.org Less <<
NCT03058601 - Completed - United Kingdom ... More >> Luton, United Kingdom Less <<
NCT00528411 - Completed - -
NCT01276275 - Completed - Sweden ... More >> Research Site Stockholm, Sweden Less <<
NCT02615704 - Active, not recruiting February 15, 2019 Germany ... More >> Research Site Bad Berka, Germany, 99437 Research Site Bad Bevensen, Germany, 29549 Research Site Bad Krozingen, Germany, 79189 Research Site Barby, Germany, 39249 Research Site Berlin-Tegel, Germany, 13507 Research Site Berlin, Germany, 12203 Research Site Berlin, Germany, D-13353 Research Site Bernau, Germany, 16321 Research Site Chemnitz, Germany, 09116 Research Site Coburg, Germany, 96450 Research Site Düsseldorf, Germany, 40217 Research Site Erkrath, Germany, 40699 Research Site Essen, Germany, 45219 Research Site Frankfurt, Germany, 65929 Research Site Gelsenkirchen, Germany, 45891 Research Site Hamburg, Germany, 20099 Research Site Heidelberg, Germany, 69120 Research Site Kassel, Germany, 34117 Research Site Kassel, Germany, 34121 Research Site Kiel, Germany, 24105 Research Site Kleve, Germany, 47533 Research Site Lübeck, Germany, 23560 Research Site Mainz, Germany, 55131 Research Site Mönchengladbach, Germany, 41063 Research Site Münster, Germany, 48149 Research Site Oldenburg, Germany, 26133 Research Site Regensburg, Germany, 93053 Research Site Rostock, Germany, 18057 Research Site Rotenburg, Germany, 36199 Research Site Siegen, Germany, 57072 Research Site Wuppertal, Germany, 42117 Less <<
NCT01813435 Coronary Artery Disease (CAD) Phase 3 Completed - -
NCT03150667 Chronic Kidney Diseases ... More >> Acute Coronary Syndrome Less << Phase 4 Recruiting April 30, 2020 United States, North Carolina ... More >> Durham VA Medical Center Recruiting Durham, North Carolina, United States, 27705 Contact: Sunil Rao, MD    919-286-0411    sunil.rao@va.gov    Contact: Marc Samsky, MD       marc.samsky@dule.edu    Principal Investigator: Sunil Rao, MD          United States, Texas VA North Texas Health Care System Recruiting Dallas, Texas, United States, 75216 Contact: Subhash Banerjee, MD    214-857-1608    subhash.banerjee@utsouthwestern.edu    Contact: Amutharani Baskar, MBBS    214-857-0305    amutharani.baskar@va.gov Less <<
NCT02627950 Acute Myocardial Infarction Phase 4 Unknown September 2017 Germany ... More >> University of Luebeck Recruiting Luebeck, Germany, 23538 Contact: Holger Thiele       holger.thiele@uksh.de    Contact: Roza Meyer-Saraei       roza.meyer-saraei@uksh.de    Principal Investigator: Holger Thiele Less <<
NCT02214654 - Unknown June 2015 China, Tianjin ... More >> Tianjin First Central Hospital Not yet recruiting Tianjin, Tianjin, China, 300192 China Tianjin First Central Hospital Not yet recruiting Tianjin, China, 300192 Contact: Xiaofei Wang, doctor       wangxiaofei@medmail.com.cn Less <<
NCT02032290 Acute Coronary Syndrome: ... More >> Non ST Elevation Myocardial Infarction ST Elevation Myocardial Infarction Unstable Angina Less << Phase 4 Unknown - Italy ... More >> Massimo Mancone Not yet recruiting Rome, Italy, 00100 Contact    00390649970468       Principal Investigator: massimo mancone, PhD Less <<
NCT02683707 - Completed - -
NCT03430661 Healthy Phase 1 Recruiting June 30, 2019 United States, New Jersey ... More >> Biotrial Inc Recruiting Newark, New Jersey, United States, 07103 Less <<
NCT02120092 Acute Coronary Syndrome Phase 2 Completed - Austria ... More >> Medical University of Vienna Vienna, Austria, 1090 Less <<
NCT02169596 Acute Coronary Syndome Phase 4 Completed - United Kingdom ... More >> Castle Hill Hospital (Hull and east Yorkshire Hospitals NHS Trust) Cottingham, East Yorkshire, United Kingdom, HU16 5JQ Less <<
NCT02683707 Coronary Artery Disease Phase 4 Completed - United States, Maryland ... More >> Johns Hopkins Hospital and University School of Medicicine Baltimore, Maryland, United States, 21287 Less <<
NCT02044146 Acute Coronary Syndrome ... More >> Percutaneous Coronary Intervention Less << Phase 2 Phase 3 Completed - Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y4W7 Canada, Quebec Montreal Heart Institute Montreal, Quebec, Canada, H1T1C8 Less <<
NCT01225562 Myocardial Infarction ... More >> Cardiovascular Death Atherothrombosis Stroke Less << Phase 3 Completed - -
NCT02032303 Acute Coronary Syndrome ... More >> Non ST Elevation Myocardial Infarction ST Elevation Myocardial Infarction Unstable Angina Less << Phase 4 Unknown - Italy ... More >> Massimo Mancone Not yet recruiting Rome, Italy, 00100 Contact    00390649970468       Principal Investigator: massimo mancone Less <<
NCT02408224 - Completed - India ... More >> Research Site Hyderabad, Andhra Pradesh, India Research Site Vijayawada, Andhra Pradesh, India Research Site Patna, Bihar, India Research Site New Delhi, Delhi, India Research Site Ahmedabad, Gujarat, India Research Site Rajkot, Gujarat, India Research Site Surat, Gujarat, India Research Site Vadodara, Gujarat, India Research Site Gurgaon, Haryana, India Research Site Srinagar, Jammu And Kashmir, India Research Site Bangalore, Karnataka, India Research Site Bengaluru, Karnataka, India Research Site Mysore, Karnataka, India Research Site Kolenchery, Kerala, India Research Site Thrissur, Kerala, India Research Site Mumbai, Maharashtra, India Research Site Nasik, Maharashtra, India Research Site Pune, Maharashtra, India Research Site Delhi, New Delhi, India Research Site Bhubaneswar, Odisha, India Research Site Ludhiana, Punjab, India Research Site Mohali, Punjab, India Research Site Jaipur, Rajasthan, India Research Site Chennai, Tamil Nadu, India Research Site Coimbatore, Tamil Nadu, India Research Site Madurai, Tamil Nadu, India Research Site Hyderabad, Telangana, India Research Site Lucknow, Uttar Pradesh, India Research Site Noida, Uttar Pradesh, India Research Site Durgapur, West Bengal, India Research Site Kolkata, West Bengal, India Less <<
NCT00721448 Pharmacokinetics Phase 1 Completed - China ... More >> Research Site Beijing, China Less <<
NCT01225562 - Completed - -
NCT01743937 Ischemic Preconditioning Phase 4 Terminated(Sponsor terminated ... More >>due to budgetary issue) Less << - United States, Texas ... More >> Dallas Veterans Affairs Medical Center Dallas, Texas, United States, 75216 UT Southwestern Medical Center Dallas, Texas, United States, 75390 Less <<
NCT01595854 Healthy Phase 1 Completed - Germany ... More >> 1160.141.1 Boehringer Ingelheim Investigational Site Biberach, Germany Less <<
NCT01734772 Healthy Phase 1 Completed - Germany ... More >> 1160.142.1 Boehringer Ingelheim Investigational Site Biberach, Germany Less <<
NCT01734772 - Completed - -
NCT03481257 - Completed - Korea, Republic of ... More >> Seoul National University Bundang Hospital Seongnam, Gyeonggi-do, Korea, Republic of, 463707 Less <<
NCT01595854 - Completed - -
NCT01738100 ST-Segment Elevation Myocardia... More >>l Infarction Less << Phase 2 Unknown December 2016 Korea, Republic of ... More >> Samsung Medical Center Recruiting Seoul, Gang nam-Gu, Ilwon-Dong, Korea, Republic of, 135-710 Contact: Hyeon-Cheol Gwon, PhD    82-2-3410-6653    hcgwon@skku.edu    Contact: Joo-Yong Hahn, PhD    82-2-3410-6653    jy.hahn@samsung.com Less <<
NCT00685906 Healthy Phase 1 Completed - United States, Florida ... More >> Research Site Miami, Florida, United States Less <<
NCT01757483 - Completed - Canada, Quebec ... More >> Research Site Montreal, Quebec, Canada Less <<
NCT01846559 Healthy Phase 4 Completed - United Kingdom ... More >> Sheffield Clinical Research Facility Sheffield, South Yorkshire, United Kingdom, S5 7AU Less <<
NCT02327624 Coronary Artery Disease Phase 4 Active, not recruiting July 2018 United Kingdom ... More >> Sheffield Teaching Hospitals NHS FT Sheffield, United Kingdom Less <<
NCT01294462 Acute Coronary Syndrome ... More >> Percutaneous Coronary Intervention Less << Phase 3 Completed - -
NCT01690884 Coronary Artery Disease Phase 1 Completed - United States, Tennessee ... More >> Autonomic Dysfunction Center Nashville, Tennessee, United States, 37232 Less <<
NCT03197298 - Completed - Netherlands ... More >> Medisch Spectrum Twente Enschede, Netherlands Less <<
NCT01294462 - Completed - -
NCT01700322 Coronary Artery Disease Phase 4 Completed - Germany ... More >> 2 Medical Clinic Mainz, Germany, 55131 Less <<
NCT02293395 Acute Coronary Syndrome Phase 2 Completed - -
NCT02913469 ST-segment Elevation Myocardia... More >>l Infarction Less << Phase 4 Unknown December 2016 China ... More >> Cardiology Department, Chinese Armed Police Force Genral Hospital, Beijing China Recruiting Beijing, China, 100039 Contact: HUILIANG LIU, MD    +8610-57976531    liuhuiliang1961@163.com    Contact: JIAO ZHANG, MD    +8615011558161    15011558161@163.com Less <<
NCT01870921 Acute Coronary Syndrome PHASE4 COMPLETED 2015-09-30 Research Site, Beijing, 100006... More >>, China|Research Site, Beijing, 100029, China|Research Site, Beijing, 100037, China|Research Site, Beijing, 100050, China|Research Site, Beijing, 100083, China|Research Site, Beijing, 100730, China|Research Site, Changchun, 130021, China|Research Site, Chengdu, 610041, China|Research Site, Chuangchun, 130041, China|Research Site, Fuzhou, 350001, China|Research Site, Fuzhou, China|Research Site, Guangzhou, 510080, China|Research Site, Guangzhou, 510220, China|Research Site, Jinan, 250012, China|Research Site, Jinan, 250021, China|Research Site, Jinan, 250033, China|Research Site, Jining, 272011, China|Research Site, Kunming, 650032, China|Research Site, Nanjing, 210009, China|Research Site, Nanjing, 210012, China|Research Site, Nanjing, 210029, China|Research Site, Shanghai, 200025, China|Research Site, Shanghai, 200433, China|Research Site, Shanghai, China|Research Site, Shenyang, 110001, China|Research Site, Shenyang, 110016, China|Research Site, Shenzhen, 518003, China|Research Site, Shenzhen, 518020, China|Research Site, Shenzhen, 518036, China|Research Site, Taiyuan, 030001, China|Research Site, Wuhan, CN-430022, China|Research Site, Wuxi, 214023, China|Research Site, Xiamen, 361004, China|Research Site, Xian, 710032, China|Research Site, Xian, 710061, China|Research Site, Xuzhou, 221006, China|Research Site, Zhengzhou, 450000, China|Research Site, Zhengzhou, 450012, China|Research Site, Zhongshan, 528403, China Less <<
NCT02293395 - Completed - -
NCT01869309 Coronary Artery Disease Phase 4 Unknown December 2016 United States, Maryland ... More >> Sinai Center for Thrombosis Research Recruiting Baltimore, Maryland, United States, 21215 Contact: Kevin P Bliden, B.S. MBA    410-601-4795    kbliden@lifebridgehealth.org    Contact: Tania B Gesheff, MSN    4106014795    tgesheff@lifebridgehealth.org Less <<
NCT01870921 Acute Coronary Syndrome PHASE4 COMPLETED 2015-09-30 Research Site, Beijing, 100006... More >>, China|Research Site, Beijing, 100029, China|Research Site, Beijing, 100037, China|Research Site, Beijing, 100050, China|Research Site, Beijing, 100083, China|Research Site, Beijing, 100730, China|Research Site, Changchun, 130021, China|Research Site, Chengdu, 610041, China|Research Site, Chuangchun, 130041, China|Research Site, Fuzhou, 350001, China|Research Site, Fuzhou, China|Research Site, Guangzhou, 510080, China|Research Site, Guangzhou, 510220, China|Research Site, Jinan, 250012, China|Research Site, Jinan, 250021, China|Research Site, Jinan, 250033, China|Research Site, Jining, 272011, China|Research Site, Kunming, 650032, China|Research Site, Nanjing, 210009, China|Research Site, Nanjing, 210012, China|Research Site, Nanjing, 210029, China|Research Site, Shanghai, 200025, China|Research Site, Shanghai, 200433, China|Research Site, Shanghai, China|Research Site, Shenyang, 110001, China|Research Site, Shenyang, 110016, China|Research Site, Shenzhen, 518003, China|Research Site, Shenzhen, 518020, China|Research Site, Shenzhen, 518036, China|Research Site, Taiyuan, 030001, China|Research Site, Wuhan, CN-430022, China|Research Site, Wuxi, 214023, China|Research Site, Xiamen, 361004, China|Research Site, Xian, 710032, China|Research Site, Xian, 710061, China|Research Site, Xuzhou, 221006, China|Research Site, Zhengzhou, 450000, China|Research Site, Zhengzhou, 450012, China|Research Site, Zhongshan, 528403, China Less <<
NCT02394145 Chronic Kidney Disease Phase 3 Unknown August 2015 Korea, Republic of ... More >> Kyung Hee University Hospital Recruiting Seoul, Korea, Republic of, 130-872 Contact: Weon Kim, MD, PhD    2-958-8170 ext 82    mylovekw@hanmail.net    Contact: Jong Shin Woo, MD    2-958-8176 ext 82    snowball77@hanmail.net    Sub-Investigator: Jong Shin Woo, MD Less <<
NCT02080858 Atrial Fibrillation ... More >> Acute Coronary Syndrome Less << Phase 1 Completed - Austria ... More >> Medical University of Vienna, Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT02639143 Inflammation ... More >>Thrombosis Less << Phase 4 Unknown April 2017 -
NCT03239067 - Recruiting July 31, 2020 China, Hubei ... More >> Tongji Hospital Recruiting Wuhan, Hubei, China, 430030 Contact: Yang Sun, MD candidate    86-27-83663280    d201578301@hust.edu.cn Less <<
NCT01957527 - Completed - Greece ... More >> Patras University Hospital Patras, Achaia, Greece, 26500 Less <<
NCT02698618 Diabetes Mellitus, Type 2 Phase 4 Unknown March 2017 Spain ... More >> Hospital Universitario Marqués de Valdecilla Not yet recruiting Santander, Cantabria, Spain, 39008 Contact: José M de la Torre, MD, PhD    +34 942202520       Principal Investigator: José M de la Torre, MD, PhD          Hospital Galdakao-Usansolo Not yet recruiting Bilbao, Vizcaya, Spain, 48960 Contact: José R Rumoroso, MD, PhD    +34 944007000       Principal Investigator: José R Rumoroso, MD, PhD          Hospital San Carlos Not yet recruiting Madrid, Spain, 28040 Contact: Javier Escaned, MD, PhD    +34913303438    javier.escaned@salud.madrid.org    Contact: Enrico Cerrato, MD       enrico.cerrato@gmail.com    Principal Investigator: Javier Escaned, MD, PhD          Sub-Investigator: Alicia Quirós, PhD Less <<
NCT01118325 Stable Coronary Artery Disease Phase 2 Completed - Japan ... More >> Research Site Mizumaki, Fukuoka, Japan Research Site Sapporo-shi, Hokkaido, Japan Research Site Toride-shi, Ibaraki, Japan Research Site Kawasaki-shi, Kanagawa, Japan Research Site Kyoto-shi, Kyoto, Japan Research Site Naha-shi, Okinawa, Japan Research Site Osaka-shi, Osaka, Japan Research Site Kusatsu-shi, Shiga, Japan Research Site Komatsushima-shi, Tokushima, Japan Research Site Shinagawa-ku, Tokyo, Japan Research Site Oita, Japan Research Site Osaka, Japan Philippines Research Site Davao City, Philippines Research Site Quezon City, Philippines Less <<
NCT03247738 ST Segment Elevation Myocardia... More >>l Infarction Percutaneous Coronary Intervention Less << Phase 4 Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT02612480 Endotoxemia Not Applicable Completed - Netherlands ... More >> Intensive Care Medicine, Radboud University Nijmegen Medical Centre Nijmegen, Gelderland, Netherlands, 6500HB Less <<
NCT02531165 Acute Myocardial Infarction Not Applicable Completed - Switzerland ... More >> Centre Hospitalier Universitaire Vaudois Lausanne, Vaud, Switzerland, 1011 Less <<
NCT02190123 - Completed - Belgium ... More >> Research Site Aalst, Belgium Research Site Baudour, Belgium Research Site Bonheiden, Belgium Research Site Brasschaat, Belgium Research Site Brugge, Belgium Research Site Brussel, Belgium Research Site Bruxelles, Belgium Research Site Charleroi, Belgium Research Site Edegem, Belgium Research Site Gent, Belgium Research Site Leuven, Belgium Research Site Liege, Belgium Research Site Mechelen, Belgium Research Site Montegnee, Belgium Research Site Ronse, Belgium Research Site Ukkel, Belgium Less <<
NCT02224274 Cardiac Arrest ... More >> Postresuscitation Syndrome Myocardial Infarction (STEMI and NSTEMI) Less << Phase 4 Completed - Slovenia ... More >> University Medical Centre Ljubljana Ljubljana, Slovenia, 1000 Less <<
NCT01118325 - Completed - -
NCT02407314 Peripheral Arterial Disease Phase 4 Terminated(AZ discontinued stu... More >>dy) Less << - United States, Arkansas ... More >> Arkansas Heart Hospital Little Rock, Arkansas, United States, 72211 Less <<
NCT02317198 Non-ST-elevation Acute Coronar... More >>y Syndrome Unstable Angina Non-ST-elevation Myocardial Infarction Less << Phase 4 Recruiting October 2019 Netherlands ... More >> St. Antonius hospital Recruiting Nieuwegein, Utrecht, Netherlands, 3430 EM Less <<
NCT02521038 - Recruiting January 2018 Korea, Republic of ... More >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Hyo-Soo Kim, MD,PhD    82-2-2072-2226 Less <<
NCT00642811 Stable Coronary Artery Disease Phase 2 Completed - United States, Arkansas ... More >> Research Site Jonesboro, Arkansas, United States United States, Florida Research Site Ormond Beach, Florida, United States United States, Maryland Research Site Baltimore, Maryland, United States United States, Ohio Research Site Cincinnati, Ohio, United States Canada, Ontario Research Site Hamilton, Ontario, Canada Canada Research Site Lachine, Canada Denmark Research Site Aalborg, Denmark Research Site Arhus, Denmark Research Site Esbjerg, Denmark United Kingdom Research Site Sheffield, United Kingdom Less <<
NCT00642811 - Completed - -
NCT02798874 Cardiovascular Diseases Not Applicable Unknown December 2016 China, Beijing ... More >> Chinese People's Liberation Army General Hospital Peking, Beijing, China, 100853 Less <<
NCT02701140 Myocardial Ischemia Phase 2 Unknown December 2017 Italy ... More >> Ospedale di grosseto - Azienda Toscana Sud- Est Not yet recruiting Grosseto, Italy, 58100 Contact: Ugo Limbruno, MD    +39 0564-483465    ulimbru@tin.it    Contact: Andrea Picchi, MD    +39 0564-414830    a.picchi@gmail.com    Catholic University of the Sacred Heart Rome, Italy, 00168 Less <<
NCT01660373 Non-ST Segment Elevation Acute... More >> Coronary Syndrome Less << Phase 3 Unknown August 2013 Korea, Republic of ... More >> Pusan National University Yangsan Hospital Recruiting Yangsan, Kyeongsangnamdo, Korea, Republic of, 626-770 Contact: June Hong Kim, MD, PhD    +82-10-8231-7171    junehongk@gmail.com    Contact: Dongcheul Han, MD    +82-10-2992-6270    usdoc12@gmail.com    Principal Investigator: June Hong Kim, MD,PhD          Sub-Investigator: Dongcheul Han, MD Less <<
NCT01504906 Healthy Phase 1 Completed - United States, Kansas ... More >> Research site Overland Park, Kansas, United States Less <<
NCT02271022 - Recruiting March 31, 2020 -
NCT02506140 Stroke Ischem... More >>ic Attack, Transient Less << Phase 2 Phase 3 Active, not recruiting March 10, 2018 China, Fujian ... More >> The First Affiliated Hospital of Fujian Medical University Fuzhou, Fujian, China, 350005 China, Guangdong The Second People's Hospital of Shenzhen Shenzhen, Guangdong, China, 518000 China, Hebei The Second Hospital of Hebei Medical University Shijiazhuang, Hebei, China, 050000 North China University of Science And Technology Affiliated Hospital Tangshan, Hebei, China, 063000 Tangshan Gongren Hospital Tangshan, Hebei, China, 063000 China, Henan The First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China, 450052 China, Hubei Wuhan Brain Hospital,General Hospital of The Yangtze River Shipping Wuhan, Hubei, China, 430014 Union Hospital,Tongji Medical College,Huazhong University of Science and Technology Wuhan, Hubei, China, 430022 Wuhan No.1 Hospital Wuhan, Hubei, China, 430022 Renmin Hospital of Wuhan University Wuhan, Hubei, China, 430060 China, Hunan Xiangya Hospital Central South University Changsha, Hunan, China, 410008 China, Jiangsu Northern Jiangsu People's Hospital,Clinical Medical School,YangZhou University Yangzhou, Jiangsu, China, 225001 China, Liaoning General Hospital of Shenyang Military Shengyang, Liaoning, China, 110016 China, Shanxi The Second Hospital of Shanxi Medical University Taiyuan, Shanxi, China, 030001 General Hospital of TISCO Taiyuan, Shanxi, China, 030003 China, Zhejiang Taizhou First People's Hospital,Huangyan Hospital of Wenzhou Medical University Taizhou, Zhejiang, China, 318020 The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China, 325000 Wenzhou Hospital of integrated Chinese and Western medicine Wenzhou, Zhejiang, China, 325000 China Aviation General Hospital of China Medical University Beijing, China, 100012 Beijing Tian Tan Hospital, Capital Medical University Beijing, China, 100050 Dongfang Hospital Beijing University of Chinese Medicine Beijing, China, 100078 The First Hospital of Fangshan District,Beijing Beijing, China, 102400 Daping Hospital,Third Military Medical University Chongqing, China, 400042 Renji Hospital,Shanghai Jiao Tong University School of Medicine Shanghai, China, 200127 Tianjin Huanhu Hospital Tianjin, China, 300350 Less <<
NCT01587651 - Completed - -
NCT03357874 Acute Coronary Syndrome Phase 3 Not yet recruiting August 2021 France ... More >> APHM Not yet recruiting Marseille, France, 13354 Contact: LAURENT BONELLO       laurent.bonello@ap-hm.fr Less <<
NCT02037412 Patients Who Are Hospitalized ... More >>and Expected to Undergo PCI for Acute Coronary Syndrome, Including Acute Myocardial Infarction and Unstable Angina. Less << Phase 4 Unknown December 2015 Korea, Republic of ... More >> Division of Cardiology, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 120-752 Contact: Myeong-Ki Hong, MD    82-2-2228-8460    mkhong61@yuhs.ac Less <<
NCT02054663 Acute Coronary Syndrome Phase 4 Completed - Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y 4W7 Less <<
NCT01523392 Stable Coronary Artery Disease Phase 4 Completed - United States, Delaware ... More >> Research Site Newark, Delaware, United States Research Site Wilmington, Delaware, United States United States, District of Columbia Research Site Washington, District of Columbia, United States United States, Florida Research Site Hollywood, Florida, United States Research Site Jacksonville, Florida, United States United States, Georgia Research Site Atlanta, Georgia, United States United States, Maryland Research Site Towson, Maryland, United States United States, Texas Research Site Beaumont, Texas, United States Less <<
NCT02201667 Acute Coronary Syndrome Phase 4 Unknown October 2016 China, Shanghai ... More >> Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University Not yet recruiting Shanghai, Shanghai, China, 200127 Contact: Ben He, MD,PhD    68383609    heben1025@hotmail.com Less <<
NCT01587651 Coronary Artery Disease Phase 4 Completed - United States, Florida ... More >> Univ. of Florida College Medicine Jacksonville, Florida, United States, 32209 Clinical Pharmacology Unit of Miami Miami, Florida, United States, 33014 Progressive Medical Research Port Orange, Florida, United States, 32127 United States, Maryland Sinai Center for Thrombosis Research Baltimore, Maryland, United States, 21215 United States, Ohio Medpace Clinical Pharmacology Unit Cincinnati, Ohio, United States, 45212 United States, South Dakota Black Hills Cardiovascular Research Rapid City, South Dakota, United States, 57701 United States, Texas West Houston Area Clinical Trial Consultants Houston, Texas, United States, 77094 Cardiology Center of Houston Katy, Texas, United States, 77450 United Kingdom University Hospital of Wales Heath Park, Cardiff, United Kingdom, CF14 4XW Bristol Heart Institute Bristol, United Kingdom, B52 8HW University Hospital Leicester Leicester, United Kingdom, LE3 9QP Southampton General Hospital Southampton, United Kingdom, SO16 6YD New Cross Hospital Wolverhampton, United Kingdom, WV10 0QP Less <<
NCT03161002 - Recruiting December 2019 China, Anhui ... More >> Anhui Provincial Hospital(The First Affiliated Hospital Of USTC) Recruiting Hefei, Anhui, China, 230001 Contact: Zhaoyi Yang, PhD    +86-0551-62283379-800    young2382@163.com    The First Affiliated Hospital of Anhui Medical University Recruiting Hefei, Anhui, China, 230001 Contact: Yan Huang, MS    +86-15056922343    hyayd123@126.com    China, Beijing Peking University First Hospital Recruiting Beijing, Beijing, China, 100034 Contact: Qian Xiang, Ph.D    +86 010 66110802    xiangqz@126.com    China, Fujian Fuzhou General Hospital of Nanjing Militray Command Recruiting Fuzhou, Fujian, China Contact: Taotao Hu, BS       412456139@qq.com    China, Henan The 7th People's Hospital Of Zhengzhou Active, not recruiting Zhengzhou, Henan, China, 450006 China, Hunan The Third Xiangya Hospital of Central South University Enrolling by invitation Changsha, Hunan, China China, Jiangxi The Second Affiliated Of Nanchang University Active, not recruiting Nanchang, Jiangxi, China, 330006 Less <<
NCT01523392 - Completed - -
NCT03551964 Acute Myocardial Infarction ... More >> Cardiogenic Shock Less << Phase 4 Recruiting June 2021 Czechia ... More >> University Hospital Kralovske Vinohrady Recruiting Prague, Please Select, Czechia, 10034 Contact: Zuzana Motovska, MD PhD    +420731573253    motovska.zuzana@gmail.com    Sub-Investigator: Jiri Knot, MD PhD          Sub-Investigator: Jaroslav Ulman, MD          St. Anne's University Hospital Brno Active, not recruiting Brno, Czechia, 656 91 Department of Cardiology, University Hospital Brno-Bohunice Not yet recruiting Brno, Czechia Contact: Petr Kala, MD. PhD.          Cardiology Department, Regional Hospital Active, not recruiting Ceske Budejovice, Czechia University Hospital Hradec Králové Active, not recruiting Hradec Králové, Czechia, 500 05 Cardiocenter, Regional Hospital Recruiting Karlovy Vary, Czechia Contact: Alexander Schee, MD          Contact       alexandr.schee@gmail.com    Krajská nemocnice Liberec Recruiting Liberec, Czechia, 460 63 Contact: Jiri Karasek, MD    +420 485 312 646    jirikarry@gmail.com    Principal Investigator: Jiri Karasek          University Hospital Olomouc Active, not recruiting Olomouc, Czechia, 77900 University Hospital Ostrava Recruiting Ostrava, Czechia, 70852 Contact: Jan Mrozek, MD    +420 596 920 115    honzamrozek@email.cz    Principal Investigator: Jan Mrozek, MD          Department of Cardiology, Regional Hospital, Active, not recruiting Pardubice, Czechia University Hospital Pilsen Recruiting Pilsen, Czechia, 304 60 Contact: Milan Hromadka, MD PhD    +00420377 103 3166    hromadka@fnplzen.cz    Principal Investigator: Milan Hromadka, MD PhD          General University Hospital in Prague Active, not recruiting Prague, Czechia, 12808 Institute of Clinical and Experimental Medicine Active, not recruiting Prague, Czechia, 14021 Na Homolce Hospital Active, not recruiting Prague, Czechia, 150 30 Cardiocenter, Hospital Podlesi Not yet recruiting Trinec, Czechia Contact: Libor Sknouril, MD. PhD.          Contact       libor.sknouril@nempodlesi.cz    Regional Hospital T. Bati Active, not recruiting Zlin, Czechia, 762 75 Masaryk Hospital Active, not recruiting Ústí Nad Labem, Czechia, 40011 Less <<
NCT02018055 - Unknown December 2016 Korea, Republic of ... More >> Seoul St.Mary's Hospital Recruiting Seoul, Korea, Republic of, 137701 Contact: KI-BAE SEUNG, M.D., Ph.D    822-2258-1142    kbseung@catholic.ac.kr    Principal Investigator: KI-BAE SEUNG, M.D., Ph.D Less <<
NCT02319941 Acute Coronary Syndrome Phase 2 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Songpa-gu, Korea, Republic of, 138-736 Less <<
NCT02247128 Aortic Valve Disease ... More >> Myocardial Infarction Stroke Bleeding Less << Phase 4 Recruiting January 2020 Belgium ... More >> Algemeen Stedelijk Ziekenhuis Recruiting Aalst, Belgium Contact: Ian Buysschaert, MD, PhD       Ian.Buysschaert@asz.be    Onze Lieve Vrouwe Ziekenhuis Recruiting Aalst, Belgium Contact: Bernard De Bruyne, MD, PhD       bernard.de.bruyne@gammas.be    Imelda Ziekenhuis Recruiting Bonheiden, Belgium Contact: John Roosen, MD       John.Roosen@imelda.be    Algemeen Ziekenhuis Sint Jan Recruiting Brugge, Belgium Contact: Luc Muyldermans, MD       Luc.Muyldermans@azsintjan.be    Ziekenhuis Oost-Limburg Recruiting Genk, Belgium Contact: Bert Ferdinande, MD       Bert.Ferdinande@zol.be    Universitair Ziekenhuis Leuven Recruiting Leuven, Belgium Contact: Christophe L.F. Dubois, MD, PhD       christophe.dubois@uzleuven.be    Czechia Charles university, Third Faculty of Medicine Recruiting Prague, Czechia Contact: Petr Tousek          Luxembourg National Institute Surgery Cardiaque Et De Cardiologie Interventionnelle Recruiting Luxembourg, Luxembourg Contact: Peter Frambach, MD, PhD       peter.frambach@incci.lu    Netherlands Academic Medical Centre (AMC) Recruiting Amsterdam, Noord Holland, Netherlands, 1105 AZ Contact: Jan Baan, MD, PhD    +31 20 566 9111    j.baan@amc.uva.nl    Isala Clinics Recruiting Zwolle, Overijssel, Netherlands, 8011 JW Contact: Rik Hermanides, MD, PhD    +31 38 424 5000    r.hermanides@isala.nl    St. Antonius Hospital Recruiting Nieuwegein, Utrecht, Netherlands, 3435CM Contact: Jurrien M ten Berg, MD, PhD    +31 88 320 1121    j.ten.berg@antoniusziekenhuis.nl    Principal Investigator: Jurrien M ten Berg, MD, PhD          Sub-Investigator: Vincent J Nijenhuis, MD          Haga Ziekenhuis Recruiting Den Haag, Netherlands Contact: Carl Schotborgh, MD, PhD       c.schotborgh@hagaziekenhuis.nl    Medisch Spectrum Twente Recruiting Enschede, Netherlands Contact: Gert K van Houwelingen, MD, PhD       K.vanHouwelingen@mst.nl    University Medical Center Not yet recruiting Groningen, Netherlands, 9700 RB Contact: P van der Harst, MD, PhD    +31 50 361 6161       Universitair Medisch Centrum Leiden Recruiting Leiden, Netherlands Contact: Frank van der Kley, MD       F.van_der_Kley@lumc.nl    Academic Hospital Recruiting Maastricht, Netherlands, 6229 HX Contact: Arnoud W.J. van 't Hof, MD, PhD    +31 43 387 6543    arnoud.vant.hof@mumc.nl    University Medical Center Utrecht (UMCU) Recruiting Utrecht, Netherlands, 3584 CX Contact: Pieter R Stella, MD, PhD    +31 88 755 5555    p.stella@umcutrecht.nl Less <<
NCT02635230 - Active, not recruiting December 2019 Netherlands ... More >> Amphia Hospital Breda, Noord-Brabant, Netherlands, 4818 CK Less <<
NCT03419325 Cardiovascular Disease (CVD) ... More >> Stroke Acute Coronary Syndrome Peripheral Arterial Disease Coronary Artery Disease Myocardial Infarction Less << Not Applicable Recruiting June 30, 2022 Puerto Rico ... More >> University Hospital at Carolina Recruiting Carolina, Puerto Rico, 00984 Contact: Angel Lopez-Candales, MD       candales33@gmail.com    Cardiovascular Hospital of Puerto Rico and the Caribbean Recruiting San Juan, Puerto Rico, 00926 Contact: Dagmar F Hernandez-Suarez, MD       dagmar.hernandez@upr.edu Less <<
NCT01947998 - Recruiting December 31, 2019 United Kingdom ... More >> Recruiting Multiple Locations, United Kingdom Less <<
NCT01952392 - Completed - France ... More >> Research Site Paris, France Less <<
NCT03533153 Myocardial Infarction Phase 1 Phase 2 Not yet recruiting May 30, 2020 -
NCT02831218 Percutaneous Transluminal Coro... More >>nary Angioplasty Less << Not Applicable Terminated(This study was merg... More >>ed into HOWTO-BRS study.) Less << - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less <<
NCT02886962 Kidney Failure, Chronic Phase 4 Recruiting January 2023 France ... More >> Service de Néphrologie et médecine interne Not yet recruiting Amiens, France, 80000 Contact: Gabriel CHOUKROUN, MD          CHRU d'Angers - Service de Néphrologie Not yet recruiting Angers, France, 49033 Contact: Virginie Besson, MD          Service Néphrologie, Dialyse, Transplantation Not yet recruiting Caen, France, 14033 Contact: Patrick HENRI, MD          Pathologie Rénale Recruiting Chambéry, France, 73000 Contact: Laure Croze, MD    0479965084       Service de Néphrologie Not yet recruiting Cherbourg-Octeville, France, 50102 Contact: Guillaume QUEFFEULOU, MD          Aural Colmar Recruiting Colmar, France, 68000 Contact: Claire BORNI DUVAL, MD       c.borni-duval@aural.asso.fr    Service de néphrologie Not yet recruiting Colmar, France, 68000 Contact: Alexandre KLEIN, MD          Service de néphrologie Not yet recruiting Dijon, France, 21000 Contact: Emmanuelle KOHLER, MD          Aurad Aquitaine Not yet recruiting Gradignan, France, 33170 Contact: Catherine LASSEUR, MD          Centre Hospitalier de Haguenau - service de Néphrologie Not yet recruiting Haguenau, France, 67504 Contact: Yves DIMITROV, MD          AURAL Haguenau Not yet recruiting Haguenau, France Contact: Yves DIMITROV       yves.dimitrov@ch-haguenau.fr    Centre Hospitalier Emile Roux Not yet recruiting Le Puy-en-Velay, France, 43000 Contact: Marc BOUILLER       marc.bouiller@ch-lepuy.fr    Clinique Bouchard Recruiting Marseille, France, 13006 Contact: Jérome SAMPOL, MD          Service de Néphrologie Not yet recruiting Nancy, France, 54511 Contact: Luc Frimat, MD          ECHO de Nantes Recruiting Nantes, France, 44000 Contact: Angelo TESTA, MD          Service de Néphrologie Not yet recruiting Nantes, France, 44093 Contact: Frédéric LAVAINNE, MD          AURA Paris Plaisance Not yet recruiting Paris, France, 75014 Contact: Maxime TOUZOT, MD          Hôpital Tenon - Service de Néphrologie Recruiting Paris, France, 75970 Contact: Hafedh FESSI, MD          Service de néphrologie Recruiting Rennes, France, 35033 Contact: Cécile VIGNEAU, MD          ECHO CA Laennec Not yet recruiting Saint-Herblain, France, 44821 Contact: Dan HRISTEA, MD          NéphroCare Tassin-Charcot Not yet recruiting Sainte-Foy-lès-Lyon, France, 69110 Contact: Guillaume JEAN, MD          AURAL st Anne Recruiting Strasbourg, France, 67000 Contact: Clotilde MULLER       Clotilde-muller@hotmail.fr    Service de Néphrologie Recruiting Strasbourg, France, 67000 Contact: Thierry Hannedouche, MD          Centre Hospitalier Bretagne-Atlantique Not yet recruiting Vannes, France, 56017 Contact: Pierre Yves DURAND, MD          Calydial CH Lucien Hussel Not yet recruiting Vienne, France, 38209 Contact: Agnès CAILLETTE BEAUDOIN, MD Less <<
NCT02402491 Percutaneous Coronary Interven... More >>tion Less << Phase 4 Unknown June 2015 China, Beijing ... More >> Beijing Anzhen Hospital Beijing, Beijing, China, 100029 Less <<
NCT02030054 Coronary Artery Disease Phase 4 Unknown September 2015 Italy ... More >> Sapienza Univeristy of Rome Not yet recruiting Rome, Italy, 00166 Contact: MD MARINA POLACCO, medicine    +393333347960    dott.mpolacco@gmail.com    Principal Investigator: MD Marina Polacco, medicine Less <<
NCT01947985 - Recruiting December 31, 2019 Netherlands ... More >> Recruiting Multiple Locations, Netherlands Less <<
NCT02605447 Coronary Artery Disease Phase 4 Active, not recruiting August 2019 -
NCT02334254 Atrial Fibrillation Phase 4 Unknown January 2016 China, Beijing ... More >> Beijing Anzhen Hospital,Capital Medical University Recruiting Beijing, Beijing, China, 100029 Contact: Fei Gao, MD    1-347-257-4916    fgaomd@163.com    Contact: Hua Shen, MD    86 13718667442    shenhua0402@163.com Less <<
NCT01947959 - Active, not recruiting December 31, 2019 Germany ... More >> Multiple Locations, Germany Less <<
NCT01385319 Coronary Artery Disease Phase 3 Unknown December 2017 Hungary ... More >> Albert Szent-Györgyi Clinical Center, University of Szeged Szeged, Hungary Italy Ospedale San Donato Arezzo, AR, Italy, 52100 Ospedali Riuniti di Bergamo Bergamo, BG, Italy, 24128 Policlinico San Marco Zingonia, BG, Italy, 24040 Ospedale di Savigliano Savigliano, CN, Italy, 12038 Istituto Clinico Sant'Ambrogio Milano, MI, Italy, 20149 Azienda Unita' Sanitaria Locale Di Modena - Ospedale Baggiovara Modena, MO, Italy, 41100 Azienda Ospedaliero-Universitaria di Parma Parma, PR, Italy, 43126 Policlinico San Matteo Pavia, PV, Italy, 27100 Ospedale di Ravenna Ravenna, RA, Italy, 48121 Azienda Ospedaliera Ordine Mauriziano di Torino, Ospedale Umberto I Torino, TO, Italy, 10128 Ospedale San Giovanni Bosco Torino, TO, Italy, 10154 University Hospital of Ferrara Ferrara, Italy, 44100 Clinica Mediterranea Naples, Italy, 80122 Portugal Hospital de Santa Cruz Carnaxide, Portugal Switzerland University Hospital of Geneva Geneva, Switzerland Less <<
NCT02377388 Platelet Aggregation During Ac... More >>ute Myocardial Infarction Less << Phase 3 Recruiting December 2019 Brazil ... More >> Heart Institute(InCor)-Acute Coronary Care Unit Recruiting São Paulo, SP, Brazil, 01406000 Contact: Paulo R Genestreti, MD    55 11 2661-5058    paulo.gen@ig.com.br    Principal Investigator: Jose C Nicolau, MD,PhD          Sub-Investigator: Paulo R Genestreti, MD Less <<
NCT02118870 Acute Coronary Syndrome Phase 4 Active, not recruiting September 2018 -
NCT01325116 Acute Myocardial Infarction ... More >> STEMI Less << Not Applicable Completed - Canada, Ontario ... More >> Hamilton Health Sciences-General Site, Heart Investigation Unit Hamilton, Ontario, Canada, L8L 2X2 Less <<
NCT02435797 Coronary Heart Disease Phase 4 Unknown October 2016 China, Jiangsu ... More >> Xuzhou Central Hospital Recruiting Xuzhou, Jiangsu, China, 221000 Contact: Feng chunguang, PhD    +8618936376559    fcg999@163.com    Sub-Investigator: Feng chunguang, PhD Less <<
NCT03184805 Coronary Artery Disease Not Applicable Terminated(Investigator judged... More >> that this study can not be maintained because participant registration rate is low.) Less << - Korea, Republic of ... More >> Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine Seoul, Korea, Republic of, 03722 Less <<
NCT03732066 Coronary Disease Not Applicable Recruiting September 30, 2020 China, Guangdong ... More >> Guangdong General Hospital Recruiting Guangzhou, Guangdong, China, 510080 Contact: Yong Liu, MD    86-020-83827812 ext 10528    liuyong2099@126.com Less <<
NCT02028234 Coronary Artery Disease Phase 4 Unknown April 2016 Italy ... More >> Sapienza Univeristy of Rome Not yet recruiting Rome, Italy, 00166 Contact: MD Marina Polacco    +393333347960    dott.mpolacco@gmail.com    Principal Investigator: MD Marina Polacco Less <<
NCT03691675 Drug-coated Balloon Not Applicable Not yet recruiting April 2019 -
NCT03606642 Coronary Artery Disease ... More >> Atherosclerosis Stent Placement Less << Phase 2 Not yet recruiting July 23, 2021 United States, Arizona ... More >> HonorHealth Research Institute Not yet recruiting Scottsdale, Arizona, United States, 85258 Contact: Joanne Saczynski, RN    480-323-1046       Principal Investigator: David G Rizik, MD          United States, Massachusetts Massachusetts General Hospital, Corrigan Minehan Heart Center Not yet recruiting Boston, Massachusetts, United States, 02114 Contact: Patricia Giunta    617-643-8769    pagiunta@mgh.harvard.edu    Principal Investigator: Farouc Jaffer, MD, PhD Less <<
NCT02212028 Coronary Artery Disease Phase 4 Completed - United States, Florida ... More >> University of Florida Jacksonville, Florida, United States, 32209 Less <<
NCT03102723 STEMI Phase 2 Recruiting July 2020 Singapore ... More >> National University Hospital (NUH) Recruiting Singapore, Singapore, 119228 Contact: A/Prof Mark Chan    67795555       Contact: Sock Cheng Poh       sock_cheng_poh@nuhs.edu.sg    Tan Tock Seng Hospital (TTSH) Recruiting Singapore, Singapore, 308433 Contact: Dr. Hee Hwa Ho    63577831       Contact: Tasha Mahadi AB    63578124    tashama@ttsh.com.sg    Khoo Teck Puat Hospital Not yet recruiting Singapore, Singapore, 768828 Contact: Lim Boon Khim    66023307       Principal Investigator: Imran Syed Saqib Less <<
NCT02724319 - Recruiting May 2019 United States, Florida ... More >> University of Florida Recruiting Jacksonville, Florida, United States, 32209 Contact: Dominick J Angiolillo, MD, PhD       dominick.angiolillo@jax.ufl.edu    Principal Investigator: Dominick J Angiolillo, MD, PhD Less <<
NCT02049762 Acute Coronary Syndrome ... More >> Platelet Function and Reactivity Tests Novel P2Y12 Inhibitors Less << Phase 4 Completed - Israel ... More >> Sheba Medical Center Tel-Hashomer, Israel, 52621 Less <<
NCT03525145 - Recruiting December 31, 2019 China, Liaoning ... More >> Northern Hospital Recruiting Shenyang, Liaoning, China Contact: Yaling Han, Dr    +86-24-23922184    13998847715@qq.com    Principal Investigator: Yaling Han, MD          Sub-Investigator: Yi Li, MD Less <<
NCT03048019 - Recruiting May 29, 2019 United States, Virginia ... More >> Inova Health Care System Recruiting Falls Church, Virginia, United States, 22042 Contact: Kevin Bliden, BS, MBA    703-776-7702    kevin.bliden@inova.org Less <<
NCT02601157 Stable Angina ... More >> Unstable Angina Non-ST Segment Elevation Myocardial Infarction Less << Phase 4 Recruiting - Korea, Republic of ... More >> Busan Paik Hospital Not yet recruiting Busan, Korea, Republic of Contact: Tae-Hyun Yang, M.D., PhD       yangthmd@naver.com    Kosin University Gospel Hospital Not yet recruiting Busan, Korea, Republic of Contact: Tae-Joon Cha, M.D., PhD       chatjn@gmail.com    SoonChunHyang University Cheonan Hospital Recruiting Cheonan, Korea, Republic of Contact: Seung Jin Lee, M.D., PhD       drlsj3@gmail.com    Chonnam National University Hospital Recruiting Gwangju, Korea, Republic of Contact: Myung-Ho Jeong, M.D., PhD       mhjeong@chonnam.ac.kr    Gwangju Christian Hospital Recruiting Gwangju, Korea, Republic of Contact: Seung Uk Lee, M.D., PhD       cardiosu@hanmail.net    Ewha Womans University Medical Center Mokdong Hospital Not yet recruiting Seoul, Korea, Republic of Contact: Wook Bum Pyun, MD. PhD.       pwb423@ewha.ac.kr    Hallym University Kangdong Sacred Heart Hospital Not yet recruiting Seoul, Korea, Republic of Contact: Kyu-Rock Han, MD. PhD.       krheart@hallym.or.kr    Kangnam Sacred Heart Hospital Not yet recruiting Seoul, Korea, Republic of Contact: Namho Lee, M.D., PhD       namholee@hallym.or.kr    Korea University Guro Hospital Recruiting Seoul, Korea, Republic of Contact: Jin Won Kim, M.D., PhD       kjwmm@korea.ac.kr    Kyung Hee University Hospital at Gangdong Not yet recruiting Seoul, Korea, Republic of Contact: Jin-Man Cho, M.D., PhD       aceri@medimail.co.kr    Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Hyo-Soo Kim, M.D., PhD    82-2-2072-2226    hyosoo@snu.ac.kr    Ajou University Hospital Recruiting Suwon, Korea, Republic of Contact: Myeong-Ho Yoon, M.D., PhD       yoonmh65@hanmail.net Less <<
NCT03342521 - Recruiting June 30, 2019 France ... More >> CAEN University Hospital Recruiting Caen, France, 14000 Contact: vincent ROULE, MD    +33231063048    roule-v@chu-caen.fr    Contact: Farzin BEYGUI, MD PhD    +33231063350    beygui-f@chu-caen.fr    Sub-Investigator: adrien LEMAITRE, MD          Sub-Investigator: mathieu BIGNON, MD          Sub-Investigator: rémi SABATIER, MD          Sub-Investigator: katrien BLANCHART, MD          Sub-Investigator: pierre ARDOUIN, MD Less <<
NCT01954303 - Completed - -
NCT03363035 Acute Coronary Syndrome ... More >> Myocardial Infarction Myocardial Ischemia Unstable Angina Less << Phase 4 Recruiting May 31, 2020 China, Hunan ... More >> The First People's Hospital of Changde City Recruiting Changde, Hunan, China, 415003 Contact: Liangqing Ge, Ph.D.    +86 13973652828    geliangqing@163.com    Changsha Central Hospital Recruiting Changsha, Hunan, China, 410004 Contact: Luping Jiang, Ph.D.    +86 18374892303    lukejlp@126.com    Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University Recruiting Changsha, Hunan, China, 410005 Contact: Zhaofen Zheng, Ph.D.    +86 13974829586    zhaofenz@foxmail.com    The Forth Hospital of Changsha Not yet recruiting Changsha, Hunan, China, 410006 Contact: Hao Gong, M.D.    +86 13873182948    949527198@qq.com    The First Affiliated Hospital of Hunan University of Chinese Medicine Not yet recruiting Changsha, Hunan, China, 410007 Contact: Yizhi Wu, M.D.    +86 18008485122    yywyz@medmail.com.cn    The Second Xiangya Hospital of Central South University Recruiting Changsha, Hunan, China, 410011 Contact: Shenghua Zhou          The First Hospital of Changsha Recruiting Changsha, Hunan, China, 410013 Contact: Guang Fu, M.D.    +86 13755170528    fuguangyisheng@163.com    The Third Xiangya Hospital of Central South University Recruiting Changsha, Hunan, China, 410013 Contact: Weihong Jiang, Ph.D.    +86 13786113632    jwhxy3@126.com    The Third Hospital of Changsha Not yet recruiting Changsha, Hunan, China, 410015 Contact: Yumin Zhang, M.D.    +86 13574145995    20428251@qq.com    The Second People's Hospital of Hunan Province Not yet recruiting Changsha, Hunan, China, 430100 Contact: Xiang Liu, M.D.    +86 13975198853    liuxiang_0927@163.com    The First People's Hospital of Chenzhou Not yet recruiting Chenzhou, Hunan, China, 423000 Contact: Zhonghua Wang, M.D.    +86 13975521597    105025@sina.com    The First Affiliated Hospital of University of South China Recruiting Hengyang, Hunan, China, 421001 Contact: Changhui Liu, Ph.D.    +86 13786435885    liuchanghuidaoshi@163.com    The Second Affiliated Hospital of University of South China Recruiting Hengyang, Hunan, China, 421001 Contact: Gaofeng Zeng, Ph.D.    +86 13873418573    2379795177@qq.com    The First Affiliated Hospital of Hunan University of Medicine Not yet recruiting Huaihua, Hunan, China, 418000 Contact: Youliang Huang, M.D.    +86 13974501620    1469477867@qq.com    The First People's Hospital of Huaihua Recruiting Huaihua, Hunan, China, 418000 Contact: Qiang Shen, M.D.    +86 13974531980    337825375@qq.com    The First Affiliated Hospital of Jishou University Not yet recruiting Jishou, Hunan, China, 416000 Contact: Can Zhu, M.D.    +86 13907439435    zc0629@163.com    The First People's Hospital of Loudi Not yet recruiting Loudi, Hunan, China, 417000 Contact: Huaqing Tan, M.D.    +86 13607389129    1063543926@qq.com    The Central Hospital of Shaoyang Recruiting Shaoyang, Hunan, China, 422000 Contact: Zewei Ouyang, M.D.    +86 13337391467    zwycy4137@126.com    Xiangtan Central Hospital Recruiting Xiangtan, Hunan, China, 411413 Contact: He Huang, M.D.    +86 13607327390    hh13607327390@126.com    Xiangxiang People's Hospital Recruiting Xianxiang, Hunan, China, 411400 Contact: Chonglun Zhou, M.D.    +86 13975236189    897236609@qq.com    Yiyang Central Hospital Recruiting Yiyang, Hunan, China, 413000 Contact: Xianming Wu, M.D.    +86 13973741819    13973741819@163.com    Yongzhou First People's Hospital Recruiting Yongzhou, Hunan, China, 425000 Contact: Zhen Zhou, Ph.D    +86-0746-6777871    56197562@qq.com    The First People's Hospital of Yueyang Recruiting Yueyang, Hunan, China, 414000 Contact: Xiping Xu, M.D.    +86 13807302918    xxps@sina.com    Zhuzhou Central Hospital Recruiting Zhuzhou, Hunan, China, 412007 Contact: Fan Ouyang, Ph.D.    +86 13307327791    1641261977@qq.com Less <<
NCT01589978 - Completed - -
NCT02212028 - Completed - -
NCT03675347 - Recruiting November 2019 Italy ... More >> San Giovanni Battista Recruiting Torino, Italy Contact: fabrizio dascenzo, doctor    3391390253    fabrizio.dascenzo@gmail.com Less <<
NCT01589978 Coronary Artery Disease Phase 4 Completed - -
NCT03146858 Primary Percutaneous Coronary ... More >>Intervention Less << Phase 4 Completed - United Kingdom ... More >> Sheffield Teaching Hospitals NHS Foundation Trust Sheffield, South Yorkshire, United Kingdom, S5 7AU Less <<
NCT03558295 - Recruiting December 31, 2018 Italy ... More >> Città della Salute e della Scienza di Torino Recruiting Torino, Piemonte, Italy, 10100 Contact: Fabrizio D'Ascenzo, MD    +390116335570    fabrizio.dascenzo@gmail.com    Principal Investigator: Fabrizio D'Ascenzo, MD          Sub-Investigator: Mattia Peyracchia, MD Less <<
NCT03746782 - Recruiting July 2019 United States, Tennessee ... More >> CirQuest Labs, LLC Recruiting Memphis, Tennessee, United States, 38112 Contact: Carol Hendrix, MSN, RN    901-866-1700    chendrix@cirquestlabs.com    Contact: Edward Hord, BSN, RN    901-866-1700    ehord@cirquestlabs.com    Principal Investigator: Jayaprakash Kotha, PhD          Sub-Investigator: Frank McGrew, MD          Sub-Investigator: Lisa Jennings, PhD Less <<
NCT03477331 - Recruiting January 14, 2022 Switzerland ... More >> Hôpital des trois-Chênes Recruiting Chemin Du Pont-Bochet 3, Thônex, Switzerland, 1226 Contact: Jean Terrier, Dr    022 305 61 11    jean.terrier@hcuge.ch Less <<
NCT01930773 Stable Angina Phase 3 Recruiting May 2018 Hungary ... More >> Heart Center Balatonfüred Active, not recruiting Balatonfüred, Hungary, 8230 Poland 1st Department of Cardiology, Medical University of Warsaw Recruiting Warsaw, Poland, 02-097 Contact: Lukasz Koltowski, MD, PhD       lukasz@koltowski.com    Contact: Mariusz Tomaniak, MD       mariusz.tomaniak@interia.pl    Principal Investigator: Lukasz Koltowski, MD          Sub-Investigator: Mariusz Tomaniak, MD Less <<
NCT01369186 Drug Interaction Potentiation ... More >> Myocardial Infarction Less << Phase 4 Completed - Austria ... More >> Medical University of Vienna, Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT03718429 Coronary Artery Disease ... More >> Peripheral Arterial Disease Atrial Fibrillation Less << Phase 4 Not yet recruiting December 2020 United States, Florida ... More >> Cardiovascular Research Center, Not yet recruiting Jacksonville, Florida, United States, 32206 Contact: Dominick J Angiolillo, MD, PhD       dominick.angiolillo@jax.ufl.edu    UF Health Jacksonville Not yet recruiting Jacksonville, Florida, United States, 32209 Contact: Dominick J Angiolillo, MD, PhD       dominick.angiolillo@jax.ufl.edu    Principal Investigator: Dominick J Angiolillo, MD, PhD Less <<
NCT02468102 - Recruiting April 1, 2020 Sweden ... More >> Many Locations Recruiting Multiple Locations, Sweden Less <<
NCT02311231 ST-segment Elevation Myocardia... More >>l Infarction Non ST-segment Elevation Myocardial Infarction Less << Phase 4 Completed - Sweden ... More >> Lund University Lund, Sweden, 221 85 Less <<
NCT01992484 - Unknown - Austria ... More >> Medical Univerity of Vienna, Department of Cardiology Recruiting Vienna, Austria Principal Investigator: Jolanta M Siller-Matula, PD MD PhD          Principal Investigator: Georg Delle-Karth, MD Less <<
NCT02741817 Acute Coronary Syndrome Phase 4 Completed - United Kingdom ... More >> Sheffield Teaching Hospitals NHS Foundation Trust Sheffield, South Yorkshire, United Kingdom, S57AU Less <<
NCT01967615 - Completed - -
NCT02026713 Coronary Artery Disease Phase 4 Unknown July 2015 Italy ... More >> Sapienza University of Rome Recruiting Rome, Roma, Italy Contact: Marina Polacco    3333347960    dott.mpolacco@gmail.com Less <<
NCT02303717 Coronary Artery Disease Not Applicable Not yet recruiting December 2020 -
NCT02251249 Impairment of Gastric Emptying... More >> Acute Phase of Myocardial Infarction Less << Phase 4 Recruiting June 8, 2017 France ... More >> CHU de Bordeaux - Hôpital du Haut Lévèque Recruiting Pessac, France, 33604 Contact: Lionel LEROUX, MD       lionel.leroux@chu-bordeaux.fr    Sub-Investigator: Frédéric CASASSUS, MD          Principal Investigator: Lionel LEROUX, MD          Sub-Investigator: Gérard BARBERO, MD          Sub-Investigator: Patricia BERNADET, MD          Sub-Investigator: Séverine BOUCARD, MD          Sub-Investigator: Philippe BOUFFARD, MD          Sub-Investigator: Olivier CASSONE, MD          Sub-Investigator: Céline CHAUVEAU, MD          Sub-Investigator: Benjamin CLOUZEAU, MD          Sub-Investigator: Guillaume DELBAST, MD          Sub-Investigator: Corinne DUBOIS-GONET, MD          Sub-Investigator: Sébastien FRANC, MD          Sub-Investigator: Hervé FRANCES, MD          Sub-Investigator: Cédric GIL JARDINE, MD          Sub-Investigator: Julie GOUGES, MD          Sub-Investigator: Nathalie GOULOIS, MD          Sub-Investigator: Virginie HEYDEL, MD          Sub-Investigator: Philippe LABADIE, MD          Sub-Investigator: Laure MAUGEIN, MD          Sub-Investigator: François ORCIVAL, MD          Sub-Investigator: Emilie RESPLANDY, MD          Sub-Investigator: Philippe REVEL, MD          Sub-Investigator: Béatrice SALAUN, MD          Sub-Investigator: Aurélie SAN MIGUEL, MD          Sub-Investigator: Oriana SANCHEZ, MD          Sub-Investigator: Bruno SIMONNET, MD          Sub-Investigator: Eric TENTILLIER, MD          Sub-Investigator: Michel THICOIPE, MD          Sub-Investigator: Grégoire VERSMEE, MD Less <<
NCT01774955 - Completed - Greece ... More >> Patras University Hospital Patras, Achaia, Greece, 26500 G.Gennimatas General Hospital Athens, Attica, Greece University Hospital, Alexandroupolis Alexandroupolis, Greece 1st Department of Cardiology, Ippokration Hospital Athens, Greece Alexandra Hospital, Athens, Greece Athens, Greece Onassis Cardiac Surgery Center Athens, Greece University Hospital, Ioannina Ioannina, Greece Iraklion University Hospital, Iraklion, Greece Iraklion, Greece Larissa University Hospital Larissa, Greece Less <<
NCT03231059 - Active, not recruiting December 30, 2018 Austria ... More >> Wilhelminenspital 1160 Vienna, Austria Belgium Research centre Bonheiden 3204 Bonheiden, Belgium Research centre Charleroi 3202 Charleroi, Belgium Research centre Genk 3205 Genk, Belgium Research centre Hasselt 3203 Hasselt, Belgium Bulgaria Research centre Sofia, 9901 Sofia, Bulgaria Germany Research centre Bad Nauheim 4902 Bad Nauheim, Germany Research centre Essen 4903 Essen, Germany Italy Research centre Arezzo 3902 Arezzo, Italy Research centre Ferrara 3905 Ferrara, Italy Research centre Pavia 3903 Pavia, Italy Research centre Terni 3909 Terni, Italy Netherlands Research centre Amsterdam 3104 Amsterdam, Netherlands Research centre Rotterdam 3101 Rotterdam, Netherlands Poland Research centre Chrzanow 4802 Chrzanów, Poland Research centre Dabrowa Gornicza 4801 Dąbrowa Górnicza, Poland Research centre Krakov 4807 Kraków, Poland Switzerland Inselspital Bern University Hospital Bern, Switzerland, 3010 United Kingdom Research centre Blackburn 4404 Blackburn, United Kingdom Less <<
NCT02264912 - Recruiting July 2018 Czechia ... More >> Faculty Hospital Kralovske Vinohrady Recruiting Prague, Czechia, 10034 Contact: Zuzana Motovska, MD. PhD.    +420267163760    zuzana.motovska@fnkv.cz    Contact: Martina Ondrakova, MD.    +420267163760    martina.ondrakova@fnkv.cz Less <<
NCT02929888 Acute Myocardial Infarction Phase 2 Phase 3 Unknown - Spain ... More >> Fundacion Recruiting Madrid, Spain, 28040 Contact: David Vivas, MD, PhD    0034913303149 ext 3149    dvivas@secardiologia.es Less <<
NCT02500290 - Recruiting March 2019 Spain ... More >> Hospital de Jerez Recruiting Cádiz, Spain Contact: Jose Julián Arias Garrido, MD       jjarias55@hotmail.com    Principal Investigator: Jose Julián Arias Garrido, MD          Hospital de Puerto Real Recruiting Cádiz, Spain Contact: Juan Carlos Rodríguez Yañez, MD       rodya3@gmail.com    Principal Investigator: Juan Carlos Rodríguez Yañez, MD          Hospital Universitario Reina Sofía Recruiting Córdoba, Spain Contact: Gemma Alonso Muñoz, MD       gema-aaron@hotmail.com    Principal Investigator: Gemma Alonso Muñoz, MD          Sub-Investigator: Miguel Angel Chirosa Ríos, MD          Sub-Investigator: Tania Amat Serna, MD          Hospital Universitario Virgen de las Nieves Recruiting Granada, Spain Contact: Antonio Reina Toral, MD       antoniorein@gmail.com    Principal Investigator: Antonio Reina Toral, MD          Hospital de Antequera Recruiting Málaga, Spain Contact: Antonio Varela López, MD       varela.anto@gmail.com    Principal Investigator: Antonio Varela López, MD          Hospital Regional de Málaga Recruiting Málaga, Spain Contact: José Andrés Arboleda Sánchez, MD       arboledaja@gmail.com    Principal Investigator: José Andrés Arboleda Sánchez          Hospital Universitario Virgen de la Victoria Recruiting Málaga, Spain Contact: Ángel García Alcántara, MD       med000859@telefonica.net    Principal Investigator: Angel García Alcántara, MD          Hospital Universitario Virgen Macarena Recruiting Sevilla, Spain Contact: Manuel Almendro Delia, MD    955 00 80 00    trocor@gmail.com    Contact: Juan Carlos García Rubiera, MD       grubira@wanadoo.es    Principal Investigator: Manuel Almendro Delia, MD          Sub-Investigator: Juan Carlos García Rubira, MD          Sub-Investigator: Emilia Blanco Ponce, MD Less <<
NCT03347435 Acute Coronary Syndromes Not Applicable Terminated(Ethics Committe dec... More >>ision) Less << - Italy ... More >> Ospedale Ramazzini Carpi, Modena, Italy, 41012 Ospedale di Vaio Fidenza, Parma, Italy, 43036 Azienda Ospedaliero Universitaria di Parma Parma, Italy, 43123 Ospedale Guglielmo da Saliceto Piacenza, Italy, 29121 Less <<
NCT01477775 Acute Coronary Syndrome ... More >> Coronary Angioplasty Less << Phase 4 Unknown December 2015 Italy ... More >> Azienda Ospedaliera Pugliese Ciaccio Active, not recruiting Catanzaro, Calabria, Italy, 88100 Azienda Ospedaliera Fatebenefratelli e Oftalmico Recruiting Milano, MI, Italy, 20121 Contact: B. Cortese, MD    +393347298103    bcortese@gmail.com    Principal Investigator: Bernardo Cortese, MD          Spedali Civili di Brescia Active, not recruiting Brescia, Italy Azienda USL Sirai Recruiting Carbonia, Italy Contact: Salvatore Ierna, MD          Principal Investigator: Salvatore Ierna, MD          University Hospital of Ferrara Recruiting Ferrara, Italy, 44100 Contact: Marco Valgimigli, MD, PhD    3356478877 ext +39    vlgmrc@unife.it    Principal Investigator: Gianluca Campo, MD          Ospedale di Lodi Active, not recruiting Lodi, Italy Ospedale dei Colli, Cardiologia SUN Recruiting Naples, Italy Contact: Paolo Calabrò, MD PhD          Principal Investigator: Paolo Calabrò, MD          Ospedale degli Infermi di Rimini Recruiting Rimini, Italy Contact: Andrea Santarelli, MD          Principal Investigator: Andrea Santarelli, MD          Ospedale San Giovanni Bosco Recruiting Torino, Italy Contact: Roberto Garbo, MD          Principal Investigator: Roberto Garbo, MD          A. O. Ospedale Civile di Vimercate Recruiting Vimercate, Italy Contact: Stefano Garducci, MD          Principal Investigator: Stefano Garducci, MD          Policlinico San Marco Recruiting Zingonia, Italy Contact: Nicoletta De Cesare, MD          Principal Investigator: Nicoletta De Casare, MD Less <<
NCT02866175 Atrial Fibrillation Phase 3 Active, not recruiting June 2019 -
NCT03111420 Risk Factor, Cardiovascular ... More >> Platelet Dysfunction Due to Drugs Less << Not Applicable Active, not recruiting May 30, 2018 -
NCT02767401 Hibernation, Myocardial ... More >> Complete Occlusion of Coronary Artery Less << Phase 4 Unknown December 2018 -
NCT03447379 Coronary Artery Occlusive Dise... More >>ase Less << Not Applicable Recruiting April 30, 2021 Korea, Republic of ... More >> Gangnam Severance Hospital Recruiting Seoul, Souel, Korea, Republic of Contact: BumKee Hong, MD    82-2-2019-3311 Less <<
NCT03119012 Coronary Artery Disease ... More >> Stents Atherosclerosis Less << Phase 4 Recruiting April 2022 Korea, Republic of ... More >> Samsung Medical Center Recruiting Seoul, Korea, Republic of, 06351 Contact: Joo-Yong Hahn, MD, PhD    82-2-3410-6653    ichjy1@gmail.com    Contact: Joo Myung Lee, MD, MPH    82-2-3410-1246    drone80@hanmail.net Less <<
NCT03372785 Chronic Total Occlusion of Cor... More >>onary Artery Percutaneous Coronary Intervention Coronary Artery Disease Viable Myocardium Less << Phase 4 Enrolling by invitation December 2020 China ... More >> Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University Beijing, China Less <<
NCT03465644 Coronary Stenoses Phase 4 Not yet recruiting December 2021 Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less <<
NCT01830543 Atrial Fibrillation ... More >> Percutaneous Coronary Intervention Less << Phase 3 Completed - -
NCT02508116 Acute Coronary Syndrome ... More >> Cardiovascular Diseases Less << Not Applicable Completed - United States, Pennsylvania ... More >> Hospital of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Penn Presbyterian Medical Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01830543 - Completed - -
NCT03664388 - Recruiting February 1, 2020 Spain ... More >> Department of Cardiology, Hospital Álvaro Cunqueiro Recruiting Vigo, Pontevedra, Spain, 36312 Contact: ANDRES IÑIGUEZ ROMO, MD, PhD       andres.iniguez.romo@sergas.es Less <<
NCT02406677 Cost Sharing, Acute Coronary S... More >>yndrome Less << Phase 4 Completed - -
NCT03415386 Acute Myocardial Infarction ... More >> Left Ventricular Thrombus Less << Phase 4 Not yet recruiting June 2020 -
NCT03008083 Drug-Eluting Stents ... More >> Percutaneous Coronary Intervention Less << Phase 4 Not yet recruiting October 2022 -
NCT01526577 Acute Coronary Syndrome Phase 1 Completed - Korea, Republic of ... More >> Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Less <<
NCT03775746 Acute Coronary Syndrome Phase 4 Not yet recruiting December 2021 -
NCT02508116 - Completed - -
NCT02041650 Acute Coronary Syndrome PHASE4 COMPLETED 2025-04-17 The 2nd Affiliated Hospital of... More >> Harbin Medical University, Harbin, Heilongjiang, 150086, China Less <<
NCT01526577 - Completed - -
NCT01740479 Acute Myocardial Infarction ... More >> Coronary Artery Disease Less << Not Applicable Active, not recruiting April 2019 Canada, Ontario ... More >> Hamilton General Hospital Hamilton, Ontario, Canada, L8L2X2 Less <<
NCT03103685 Dental Diseases ... More >> Antiplatelet Agents Antiplatelet Drugs Less << Phase 4 Not yet recruiting December 30, 2018 -
NCT01761786 Myocardial Infarction ... More >> STEMI Less << Phase 4 Active, not recruiting April 2019 Belgium ... More >> OLV Hospital Aalst, Belgium Italy University of Naples Federico II Naples, Italy Netherlands Meander Medisch Centrum Amersfoort, Netherlands OLVG Amsterdam, Netherlands Rijnstate Hospital Arnhem, Netherlands Amphia Hospital Breda, Netherlands University Medical Center Groningen Groningen, Netherlands St. Antonius Hospital Nieuwegein, Netherlands University Medical Center Utrecht, Netherlands Isala Klinieken Zwolle, Netherlands Less <<
NCT01515345 Platelet Inhibition ... More >> Coronary Stent Implantation Less << Phase 3 Completed - Austria ... More >> Kaiser Franz Josef Hospital Vienna, Austria, 1100 Less <<
NCT03362788 - Recruiting June 2020 Greece ... More >> Attikon University Hospital Recruiting Athens, Attika, Greece, 12462 Contact: Dimitrios Alexopoulos, MD    306944314398    dalex@med.uoa.gr    Contact: Christos Pappas, MD    306977272299    clincard@hotmail.com Less <<
NCT02699008 Acute Coronary Syndrome Not Applicable Completed - China, Hubei ... More >> Wuhan Asia Heart Hospital Wuhan, Hubei, China, 430022 Less <<
NCT02101437 - Recruiting October 2017 Taiwan ... More >> Taipei city hospital Recruiting Taipei, Taiwan Contact: Chen Yueh Chung, chief doctor    886227093600 ext 3741    chenyuehchung.tw@yahoo.com.tw Less <<
NCT02428374 Myocardial Fibrosis Phase 4 Recruiting July 2019 Brazil ... More >> Hospital Sao Paulo - UNIFESP Recruiting Sao Paulo, Brazil, 04040001 Contact: Francisco A H Fonseca, MD, PhD    +5511992639082    fahfonseca@terra.com.br Less <<
NCT01955200 Coronary Artery Disease Phase 4 Unknown December 2016 China, Jiangsu ... More >> First Affiliated Hospital of Nanjing Medical University Recruiting Nanjing, Jiangsu, China, 210029 Contact: Fuming Zhang, M.D.    +86-25-83718836 ext 6360    jsphkj@163.com    Contact: Yi Chai, M.D.    +86-25-83718836 ext 6360    jsphkj@163.com    Sub-Investigator: Dingguo Zhang, Ph.D Less <<
NCT01515345 - Completed - -
NCT01994941 Acute Coronary Syndrome Phase 4 Completed - Hong Kong ... More >> Department of Medicine, the University of Hong Kong, Queen Mary Hospital, Hospital Authority Hong Kong, Hong Kong Less <<
NCT01739556 Acute ST-elevation Myocardial ... More >>Infarction Less << Phase 3 Terminated(An interim analysis... More >> showed that there is no difference in the primary endpoint, given the small number of events in the groups examined.) Less << - Serbia ... More >> Clinical Centre of Serbia, Emergency Hospital Belgrade, Serbia, 11000 Less <<
NCT02618837 Unstable Angina or Non ST Elev... More >>ated Myocardial Infarction Less << Phase 4 Unknown November 2018 Italy ... More >> Azienda Ospedaliera di Padova Recruiting Padova, Veneto, Italy, 35131 Contact: Giuseppe Tarantini, MD          Principal Investigator: Giuseppe Tarantini, MD          Sub-Investigator: Marco Mojoli, MD Less <<
NCT02164864 - Completed - -
NCT01701453 Acute Coronary Syndrome Not Applicable Active, not recruiting November 2019 Korea, Republic of ... More >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 Less <<
NCT02030548 - Terminated(enrolment behind ex... More >>pectation) Less << - Austria ... More >> Dept. of Anesthesiology and Intensive Care Medicine Graz, Styria, Austria, 8036 Less <<
NCT02101411 - Completed - Taiwan ... More >> Taipei City Hospital Taipei, Taiwan Less <<
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Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.91mL

0.38mL

0.19mL

9.57mL

1.91mL

0.96mL

19.14mL

3.83mL

1.91mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

[1]Teng R, Butler K. Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects. Eur J Clin Pharmacol. 2010 May;66(5):487-96.

[2]VAN Giezen JJ, Nilsson L, et al. Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation. J Thromb Haemost. 2009 Sep;7(9):1556-65.

[3]Ye Y, Birnbaum GD, et al. Ticagrelor protects the heart against reperfusion injury and improves remodeling after myocardial infarction. Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1805-14.

[4]Sugidachi A, Ohno K, et al. A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats. Br J Pharmacol. 2013 May;169(1):82-9.

[5]Lancellotti P, Musumeci L, et al. Antibacterial Activity of Ticagrelor in Conventional Antiplatelet Dosages Against Antibiotic-Resistant Gram-Positive Bacteria. JAMA Cardiol. 2019 Jun 1;4(6):596-599.

[6]Na YG, Byeon JJ, et al. Pharmacokinetic/Pharmacodynamic Modeling To Predict the Antiplatelet Effect of the Ticagrelor-Loaded Self-Microemulsifying Drug Delivery System in Rats. Mol Pharm. 2020 Feb 24.

[7]VAN Giezen JJ, Nilsson L, Berntsson P, Wissing BM, Giordanetto F, Tomlinson W, Greasley PJ. Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation. J Thromb Haemost. 2009 Sep;7(9):1556-65. doi: 10.1111/j.1538-7836.2009.03527.x. Epub 2009 Jun 23. PMID: 19552634.

[8]Zhou D, Andersson TB, Grimm SW. In vitro evaluation of potential drug-drug interactions with ticagrelor: cytochrome P450 reaction phenotyping, inhibition, induction, and differential kinetics. Drug Metab Dispos. 2011 Apr;39(4):703-10. doi: 10.1124/dmd.110.037143. Epub 2010 Dec 22. PMID: 21177984.

[9]Gebremeskel S, LeVatte T, Liwski RS, Johnston B, Bezuhly M. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015 Jan 1;136(1):234-40. doi: 10.1002/ijc.28947. Epub 2014 May 14. PMID: 24798403.

[10]Sugidachi A, Ohno K, Ogawa T, Jakubowski J, Hashimoto M, Tomizawa A. A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats. Br J Pharmacol. 2013 May;169(1):82-9. doi: 10.1111/bph.12108. PMID: 23347039; PMCID: PMC3632240.

 

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