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Structure of Tofacitinib
CAS No.: 477600-75-2
*Storage: {[sel_prStorage]}
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50 values of 1, 20, and 112 nM, respectively.
Synonyms: Tasocitinib; CP-690550
4.5
*For Research Use Only !
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 477600-75-2 |
Formula : | C16H20N6O |
M.W : | 312.37 |
SMILES Code : | N#CCC(N1C[C@H](N(C)C2=C3C(NC=C3)=NC=N2)[C@H](C)CC1)=O |
Synonyms : |
Tasocitinib; CP-690550
|
MDL No. : | MFCD11035919 |
InChI Key : | UJLAWZDWDVHWOW-YPMHNXCESA-N |
Pubchem ID : | 9926791 |
GHS Pictogram: |
![]() |
Signal Word: | Danger |
Hazard Statements: | H301-H311-H331 |
Precautionary Statements: | P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501 |
Class: | 6.1 |
UN#: | 2811 |
Packing Group: | Ⅲ |
Target |
|
In Vitro:
Concentration | Treated Time | Description | References |
Human Rheumatoid Arthritis Synovial Fibroblasts (RASFs) | 5 µM | 2 h | Inhibition of IL-6/IL-6R-induced JAK/STAT signaling pathway | PMC8593237 |
Bone marrow-derived macrophages (BMDM) | 300 nM | 24, 48, and 96 h | To evaluate the effect of Tofacitinib on TNF-α and IL-1β expression in M.tb-infected BMDM cells. Results showed that BMDM cells from C3HeB/FeJ mice expressed significantly lower levels of TNF-α and IL-1β after infection compared to BALB/c mice. The addition of Tofacitinib did not alter cytokine levels. | PMC4563140 |
CTL effectors from C3H/HeJ mice | 50 nM | 96 h | Tofacitinib blocked IL-15–triggered pSTAT5 activation and inhibited IL-15-induced upregulation of granzyme B and IFN-γ expression. | PMC4362521 |
NK-S1 | 10 nM to 10 μM | 96 h | To evaluate the effect of PRN371 on NK-S1 cell growth, results showed that PRN371 significantly inhibited NK-S1 cell growth | PMC5940653 |
CMK | 10 nM to 10 μM | 96 h | To evaluate the effect of PRN371 on CMK cell growth, results showed that PRN371 significantly inhibited CMK cell growth | PMC5940653 |
PBMCs | 150 nM | 4 days | To investigate the inhibitory effect of Tofacitinib on IL-7-induced expansion of CD28- CTLs. The results showed that Tofacitinib significantly inhibited the expansion of CD4+CD28- CTLs and CD8+CD28- CTLs induced by IL-7. | PMC9301466 |
CD3+ peripheral T cells | 10–500 nM | 3 days | Inhibited T cell proliferation, dose-dependently reduced WST-1 conversion to formazan | PMC8688178 |
CD14+ monocytes | 500 nM | 24 h | Suppressed proinflammatory cytokines IL-6, CXCL10, TNF-α, and induced anti-inflammatory cytokine IL-10 | PMC8688178 |
In Vivo:
Administration | Dosage | Frequency | Description | References |
Mice | Tuberculosis model | Oral | 30 mg/kg | Twice daily for 6 months | To evaluate the efficacy of Tofacitinib as an adjunctive therapy in standard TB chemotherapy. Results showed that BALB/c mice receiving Tofacitinib adjunctive therapy achieved apparent lung sterilization within 16 weeks, while the standard treatment group required 24 weeks. However, Tofacitinib did not shorten the time to achieve relapse-free cure. In C3HeB/FeJ mice, Tofacitinib adjunctive therapy showed no effect. | PMC4563140 |
C3H/HeJ mice | Alopecia areata model | Subcutaneous osmotic pump | 15 mg/kg | Once daily for 12 weeks | Tofacitinib prevented the development of alopecia areata and blocked the expansion of CD8+NKG2D+ T cells in the skin. | PMC4362521 |
Mice | NK-S1 subcutaneous xenograft model | Intraperitoneal injection | 25 mg/kg and 50 mg/kg | Once daily for 14 days | To evaluate the anti-tumor effect of PRN371 in the NK-S1 subcutaneous xenograft model, results showed that PRN371 significantly inhibited tumor growth | PMC5940653 |
Mice | Pdcd1−/− mice | Intraperitoneal injection | 15 mg/kg | Once daily for 3 days | To investigate the effect of Tofacitinib on the number and function of KLRG1+ ILC-2 cells, it was found that Tofacitinib significantly reduced the number of KLRG1+ ILC-2 cells and IL-13 cytokine production | PMC5461001 |
BALB/c mice | DSS-induced colitis model | Oral | 30 mg/kg | Twice daily, starting from day 4 until the end of the experiment | Ameliorated DSS-induced colitis inflammation, significantly reduced histologic severity and fecal inflammatory biomarker lipocalin 2 levels | PMC8688178 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT04332042 | SARS-COv2 Related Interstitial... More >> Pneumonia Less << | PHASE2 | UNKNOWN | 2020-07-10 | Ospedali Riuniti di Ancona, An... More >>cona, Marche, 60126, Italy Less << |
NCT05087589 | Primary Sj?gren's Syndrome | PHASE2 | UNKNOWN | 2023-10-01 | Department of Rheumatology and... More >> Immunology, Peking University People's Hospital, Beijing, Beijing, 100044, China Less << |
NCT04424303 | Ulcerative Colitis | RECRUITING | 2026-06-30 | Clinique de l Europe, Amiens, ... More >>80090, France|Hopital Sud, Amiens, 80480, France|Hopital Jean Minjoz, Besancon, 25003, France|Hopital de La Cote de Nacre, Caen, 14027, France|Centre Hospitalier de Cahors, Cahors, 46005, France|Infirmerie Protestante de Lyon, Caluire, 69300, France|Hopital Trousseau, Chambray Les Tours, 37171, France|Hopital D'Estaing, Clermont Ferrand, 63100, France|Aphp - Hopital Beaujon, Clichy Cedex, 92118, France|Ch Intercommunal de Creteil, Creteil Cedex, 94010, France|Ch Dunkerque, Dunkerque, 59385, France|Hopital Albert Michallon, La Tronche, 38700, France|Ch Bicetre, Le Kremlin Bicetre, 94275, France|CH Le Mans, Le Mans, 72037, France|Ch Emile Roux, Le Puy En Velay, 43012, France|Hopital Claude Huriez, Lille, 59037, France|Ch Saint Joseph Saint Luc, Lyon, 69365, France|Ch Montfermeil, Montfermeil, 93370, France|Hopital Saint Eloi, Montpellier Cedex 5, 34295, France|Clinique Beau Soleil, Montpellier, 34070, France|Chu Nantes, Nantes, 44004, France|Clinique Jules Verne, Nantes, 44014, France|Hopital de L'Archet, Nice, 06202, France|Hopital Caremeau, Nimes, 30029, France|Aphp - Hopital Saint Louis, Paris Cedex 10, 75466, France|Hopital Europeen Georges Pompidou, Paris, 75015, France|Groupe Hospitalier Saint Joseph, Paris, 75674, France|Chu Bichat Claude Bernard, Paris, 75877, France|Chu de Bordeaux - Hopital Haut Leveque, Pessac, 33600, France|CHU LYON, Pierre Benite, 69495, France|Ch Annecy Genevois, Pringy, 74374, France|Chu Rennes, Rennes, 35033, France|Hopital Nord, St Priest En Jarez Cedex, 42277, France|Hopital Rangueil, Toulouse cedex 04, 31403, France|Clinique Pasteur, Toulouse, 31076, France|Ch Valence, Valence, 26953, France|Ch Valenciennes, Valenciennes, 59322, France|Groupe Hospitalier Mutualiste Les Portes du Sud, Venissieux, 69694, France Less << | |
NCT04973033 | ANCA Associated Vasculitis|Dru... More >>g Use|JAK-STAT Pathway Deregulation Less << | COMPLETED | 2021-01-31 | Department of Rheumatology in ... More >>Zhongshan hospital, Fudan University, Shanghai, Shanghai, 200032, China Less << | |
NCT03288324 | Cutaneous Lupus|Systemic Lupus... More >> Erythematosus Less << | PHASE1|PHASE2 | COMPLETED | 2023-12-01 | Cincinnati Childrens Hospital ... More >>Medical Center, Cincinnati, Ohio, 45229, United States|MetroHealth Medical Center, Cleveland, Ohio, 44109, United States Less << |
NCT05246293 | Rheumatoid Arthritis|Interstit... More >>ial Lung Disease Less << | PHASE2 | RECRUITING | 2025-03-02 | Instituto Nacional de Enfermed... More >>ades Respiratorias, Ismael Cosío Villegas, Mexico City, Tlalpan, 14080, Mexico Less << |
NCT03738956 | Axial Spondyloarthritis | PHASE2|PHASE3 | UNKNOWN | 2018-12-31 | Bangabandhu sheikh mujib medic... More >>al university, Dhaka, 1205, Bangladesh Less << |
NCT02299297 | Alopecia Areata | PHASE2 | COMPLETED | 2025-12-17 | Columbia University Medical Ce... More >>nter, New York, New York, 10032, United States Less << |
NCT03011281 | Rheumatoid Arthritis | UNKNOWN | 2025-12-21 | Hanyang University, Seoul, 047... More >>63, Korea, Republic of Less << | |
NCT04175886 | Rheumatoid Arthritis | TERMINATED | 2023-05-08 | Lille University Hospital, Lil... More >>le, France Less << | |
NCT03800979 | Alopecia Areata | PHASE4 | COMPLETED | 2021-01-30 | Institute of Dermatology, Bang... More >>kok, Thailand Less << |
NCT06044844 | Efficacy of Tofacitinib in the... More >> Systemic Sclerosis Less << | PHASE2 | RECRUITING | 2025-05-24 | Nabil Amin Khan, Dhaka, Shahba... More >>g, 1217, Bangladesh Less << |
NCT03502616 | Ankylosing Spondylitis | PHASE3 | COMPLETED | 2020-08-20 | Rheumatology Associates of Nor... More >>th Alabama, PC, Huntsville, Alabama, 35801, United States|Arizona Arthritis & Rheumatology Associates, P.C., Gilbert, Arizona, 85297, United States|Medvin Clinical Research, Covina, California, 91722, United States|Rheumatology Center of San Diego PC, San Diego, California, 92128, United States|University of California, San Francisco Medical Center, San Francisco, California, 94143, United States|Robin K. Dore, MD, Inc., Tustin, California, 92780, United States|New England Research Associates, LLC, Bridgeport, Connecticut, 06606, United States|Advanced Radiology, Stamford, Connecticut, 06902, United States|Stamford Therapeutics Consortium, Stamford, Connecticut, 06905, United States|Southcoast Research Center, Inc., Miami, Florida, 33136, United States|Millennium Research, Ormond Beach, Florida, 32174, United States|Bluegrass Community Research, Inc, Lexington, Kentucky, 40504, United States|Center for Rheumatology and Bone Research, Wheaton, Maryland, 20902, United States|M3-Emerging Medical Research, LLC, Durham, North Carolina, 27704, United States|Paramount Medical Research and Consulting, LLC, Middleburg Heights, Ohio, 44130, United States|Oregon Health & Science University, Portland, Oregon, 97239, United States|Altoona Center For Clinical Research, Duncansville, Pennsylvania, 16635, United States|Articularis Healthcare Group, Inc d/b/a Low Country Rheumatology, Summerville, South Carolina, 29486, United States|Precision Comprehensive Clinical Research Solutions, Colleyville, Texas, 76034, United States|Adriana Pop-Moody MD - Clinic PA, Corpus Christi, Texas, 78404, United States|Metroplex Clinical Research Center, Dallas, Texas, 75231, United States|Clinical Research Unit, Houston, Texas, 77030, United States|Investigational Drug Services, Houston, Texas, 77030, United States|Memorial Hermann Hospital Imaging, Houston, Texas, 77030, United States|Southwest Rheumatology Research LLC, Mesquite, Texas, 75150, United States|Trinity Universal Research Associates, Inc., Plano, Texas, 75024, United States|Advanced Rheumatology of Houston, The Woodlands, Texas, 77382, United States|Arthritis Northwest, PLLC, Spokane, Washington, 99204, United States|Pacific Radiology,, Maroochydore, Queensland, 4558, Australia|Rheumatology Research Unit Sunshine Coast, Maroochydore, Queensland, 4558, Australia|Emeritus Research Pty. Ltd., Camberwell, Victoria, 3124, Australia|Melbourne Radiology Clinic, East Melbourne, Victoria, 3002, Australia|SKG Radiology, Subiaco, Western Australia, 6008, Australia|Western Cardiology, Subiaco, Western Australia, 6008, Australia|RK Will Pty Ltd, Victoria Park, Western Australia, 6100, Australia|Multiprofile Hospital for active treatment "Kaspela" EOOD, Plovdiv, 4002, Bulgaria|Diagnostic-Consulting Center XVII - Sofia, Sofia, 1505, Bulgaria|Medical Centre Synexus Sofia EOOD, Sofia, 1784, Bulgaria|Centre de Recherche Musculo-Squelettique, Trois-Rivieres, Quebec, G8Z 1Y2, Canada|G.R.M.O. (Groupe de recherche en maladies osseuses) Inc., Quebec, G1V 3M7, Canada|Guangdong Provincial People's Hospital, Guangzhou, Guangdong, 510080, China|The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510630, China|The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310009, China|The First Affiliated Hosptial of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China|Rheumatology and Immunology Department, Shanghai Changzheng Hospital, Shanghai, 200003, China|Lekarna Rezidence Nova Karolina, Ostrava, 702 00, Czechia|CCBR Ostrava s.r.o., Ostrava, 70200, Czechia|BENU Lekarna, Pardubice, 530 02, Czechia|CCR, Czech a.s., Pardubice, 530 02, Czechia|Lekarna Hradebni, s.r.o., Uherske Hradiste, 686 01, Czechia|Uherskohradistska nemocnice, a.s., Uherske Hradiste, 686 06, Czechia|Medical Plus s.r.o., Uherske Hradiste, 68601, Czechia|CHRU de Tours, Hopital Trousseau, TOURS Cedex 9, 37044, France|Qualiclinic K ft, Budapest, 1036, Hungary|Pest megyei Flór Ferenc Kórház, Reumatológia-és Fizioterápiás Osztály, Kistarcsa, 2143, Hungary|VITAL MEDICAL CENTER (VITáL-MEDICINA Kft.), Veszprém, 8200, Hungary|Barzilai Medical Center, Ashkelon, 7830604, Israel|Chonnam National University Hospital, Gwangju, 61469, Korea, Republic of|Inha University Hospital, Incheon, 22332, Korea, Republic of|Hanyang University Seoul Hospital, Seoul, 04763, Korea, Republic of|Geo Medical Sp. z.o.o Szpital Geo Medical, Katowice, 40-042, Poland|Moja Przychodnia, Katowice, 40-057, Poland|C.M. Silmedic Sp. z o.o., Katowice, 40-282, Poland|Malopolskie Badania Kliniczne Sp. z o.o. s.k., Krakow, 30-040, Poland|Samodzielny Publiczny Zaklad Opieki Zdrowotnej MSWiA, Krakow, 30-053, Poland|Centrum Medyczne Plejady, Krakow, 30-363, Poland|Centrum Medyczne LUX MED, Krakow, 30-415, Poland|Malopolskie Centrum Medyczne S.C., Krakow, 30-510, Poland|Szpital Uniwersytecki w Krakowie, Zaklad Radiologii, Krakow, 31-066, Poland|Top Medical, Lublin, 20-601, Poland|Zespol Poradni Specjalistycznych REUMED, Wallenroda Filia nr 1, Lublin, 20-607, Poland|NZOZ JAMED Pracownia Rentgenowska Jerema Antoszewski, Poznan, 61-397, Poland|Prywatna Praktyka Lekarska Prof. UM dr hab. med. Pawel Hrycaj, Poznan, 61-397, Poland|Klinika Alfa, Sochaczew, 96-500, Poland|RCMed Oddzial Sochaczew, Sochaczew, 96-500, Poland|Szpital Powiatowy w Sochaczewie, Sochaczew, 96-500, Poland|Szpital Sw. Elzbiety, Mokotowskie Centrum Medyczne, Zaklad Diagnostyki, Warszawa, 02-616, Poland|"Reumatika - Centrum Reumatologii" NZOZ, Warszawa, 02-691, Poland|Centrum Medyczne Oporow, Wroclaw, 52-416, Poland|Centrum Medyczne Medix, Wroclaw, 53-413, Poland|Limited Liability Company Medical Center "Rheuma-Med", Kemerovo, 650070, Russian Federation|State Budgetary Healthcare Institution "Orenburg Regional Clinical Hospital", Orenburg, 460018, Russian Federation|Limited Liability Company "Sanavita", Saint-Petersburg, 195257, Russian Federation|State Healthcare Institution "Regional Clinical Hospital", Saratov, 410053, Russian Federation|RSBHI "Smolensk Regional Clinical Hospital", Smolensk, 214018, Russian Federation|Limited Liability Company "BioMed", Vladimir, 600005, Russian Federation|Ankara Universitesi Tip Fakultesi Ibn-i Sina Hastanesi, Ankara, 06100, Turkey|Ankara Universitesi Tip Fakultesi, Ibn-i Sina Hastanesi, Ankara, 06100, Turkey|Hacettepe Universitesi Tip Fakultesi, Ic Hastaliklari Anabilim, Ankara, 06230, Turkey|Istanbul Universitesi Istanbul Tip Fakultesi, Ic Hastaliklari, Istanbul, 34093, Turkey|Istanbul Universitesi Istanbul Tip Fakultesi, Istanbul, 34093, Turkey|Marmara Univ. Istanbul Pendik Egitim ve Arastirma Hastanesi, Istanbul, 34899, Turkey|Izmir Katip Celebi Univ Ataturk Egitim ve Arastirma Hastanesi, Izmir, 35360, Turkey|Izmir Katip Celebi Univ. Ataturk Egitim ve Arastirma Hastanesi, Izmir, 35360, Turkey|Kyiv City Clinical Hospital # 3, Rheumatology Department, Kyiv, 02125, Ukraine|Lviv Communal Clinical Hospital #4, Rheumatology department, Lviv, 79011, Ukraine|Military-Medical Clinical Center (Clinical Hospital with 200 beds) of State Border Guard Service of, Lviv, 79014, Ukraine|Ternopil University Hospital, Department of Rheumatology,, Ternopil, 46002, Ukraine|Vinnytsia Regional Clinical Hospital n.a. M.I.Pyrohov, rheumatology department,, Vinnytsia, 21018, Ukraine Less << |
NCT06278402 | Alopecia Areata|Alopecia Total... More >>is|Alopecia Universalis Less << | PHASE3 | COMPLETED | 2024-01-16 | Misbah Zari Qadir, Karachi, Si... More >>ndh, Pakistan Less << |
NCT06310057 | Axial Spondyloarthritis | PHASE4 | COMPLETED | 2024-03-01 | Bangabandhu Sheikh Mujib Medic... More >>al University, Dhaka, 1000, Bangladesh Less << |
NCT03387423 | Arthritis, Rheumatoid | COMPLETED | 2023-07-17 | Private Praxis, Duesseldorf, N... More >>ordrhein-westfalen, 40237, Germany|Private Practice, Zschopau, Sachsen, 09405, Germany|Private Practice Kupka, Altenburg, 04600, Germany|Private Practise Boehm, Altenholz, 24161, Germany|Private Practice Marycz, Amberg, 92224, Germany|Private Practice Fuchs, Augsburg, 86157, Germany|private practise Gause, Bad Bramstedt, 24576, Germany|ACURA Kliniken Rheinland-Pfalz AG, Bad Kreuznach, 55543, Germany|MFZ Medizinisches Forschungszentrum Weserbergland, Bad Pyrmont, 31812, Germany|Private Practice Manger, Bamberg, 96047, Germany|Private Practice Ochs, Bayreuth, 95444, Germany|Private Practice Schmitt-Haendle, Bayreuth, 95444, Germany|Private Practice, Bayreuth, 95444, Germany|Ambulantes Gesundheitszentrum der Charité, Berlin, 10117, Germany|Private Practice Bozorg, Berlin, 10713, Germany|Private Practice Brandt-Juergens, Berlin, 12161, Germany|Privat Practice Remstedt, Berlin, 12435, Germany|private practise Herzberg, Berlin, 12435, Germany|Private Practice Seifert, Berlin, 12555, Germany|Private Practice Zinke, Berlin, 13055, Germany|Private Practice Thiele, Berlin, 14129, Germany|Immanuel Klinikum Bernau, Bernau, 16321, Germany|Private Practise, Braunschweig, 38100, Germany|MED Bayern OST GmbH, Burghausen, 84489, Germany|Private Practice Lorenz, Chemnitz, 09139, Germany|Private Practice Kirrstetter, Deggendorf, 94469, Germany|Kreiskranenhaus Demmin GmbH, Demmin, 17109, Germany|Private Practice Menne, Dortmund, 44263, Germany|Private Practice Luethke, Dresden, 01097, Germany|Private Practice Fischer, Dresden, 01277, Germany|private practise Pech, Eberswalde, 16225, Germany|Private Practice Steinmueller, Ehringshausen, 35630, Germany|Asklepios MVZ Nord SH GmbH, c/o AK St. Georg, Elmshorn, 25335, Germany|Private Practice Kaestner, Erfurt, 99096, Germany|Private Practice Koch, Erfurt, 99096, Germany|Private Practice Haeckel, Frankenberg/Sa., 09669, Germany|Private Practice Mueller, Freiberg, 09599, Germany|SRH Krankenhaus Waltershausen-Friedrichroda GmbH, Friedrichroda, 99894, Germany|Private Practice Abahji, Germering, 82110, Germany|Private Practice Sensse, Gifhorn, 38518, Germany|Private Practice Holst, Glaisin, 19288, Germany|Private Practice Zeh, Goeppingen, 73033, Germany|Private Practice Semmler, Guestrow, 18273, Germany|private practise Kühne, Haldensleben, 39340, Germany|Private Practice Liebhaber, Halle, 06128, Germany|Private Practice Dahmen, Hamburg, 22415, Germany|private practise Aries, Hamburg, 22767, Germany|Private Practice Stille, Hannover, 30161, Germany|private practise Heilig, Heidelberg, 69120, Germany|private practise Wernicke, Hohen Neuendorf, 16540, Germany|Private Practice Kremers, Juelich, 52428, Germany|Medius Kliniken gGmbH, Kirchheim unter Teck, 73230, Germany|Private Practice Baerlecken, Koeln, 50996, Germany|Kreiskrankenhaus Langenau, Langenau, 89129, Germany|Private Practice Hamann, Leipzig, 04109, Germany|Private Practice Schwarze, Leipzig, 04129, Germany|Private Practice Kudela, Magdeburg, 39104, Germany|private practise Sieburg, Magdeburg, 39104, Germany|Private Practice Rossbach, Mansfeld, 06343, Germany|Private Practice Harmuth, Marktredwitz, 95615, Germany|Private Practice Worsch, Muehlhausen, 99974, Germany|Private Practice Krueger, Muenchen, 81541, Germany|Private Practice Raub, Muenster, 48143, Germany|Praxis Dr.med. Holger Krauel Facharzt für Innere Medizin und Rheumatologie, Naumburg (Saale), 06618, Germany|Private Practice Berger, Naunhof, 04683, Germany|Private Practise, Neubrandenburg, 17033, Germany|Private Practice Volberg, Neuss, 41462, Germany|MCN Medic Center Nuernberg GmbH, Nuernberg, 90443, Germany|Private Practice Goettl, Passau, 94032, Germany|Private Practice Graessler, Pirna, 01796, Germany|Private Practice Baumann, Plauen, 08523, Germany|Knappschaftsklinikum Soor, Klinik fuer Rheumatologie und Klinische Immunologie, Puettlingen, 66346, Germany|Private Practice Wassenberg, Koehler, Weier, Ratingen, 40878, Germany|Private Practice Richter, Rostock, 18059, Germany|private practise Biewer, Saarbrücken, 66111, Germany|MVZ Dialysezentrum Schweinfurt, Schweinfurt, 97421, Germany|Private Practice Moebius, Schwerin, 19053, Germany|Private Practice, Schwerin, 19053, Germany|private practise St?nder, Schwerin, 19053, Germany|Private Practice Melzer, Seesen, 38723, Germany|MVZ Klinikum Straubing, Straubing, 94315, Germany|Private Practice, Templin, 17268, Germany|Private Practice Pyra, Torgelow, 17358, Germany|Private Practice Haas, Tuebingen, 72072, Germany|Klinik an der Weissenburg GmbH, Uhlstaedt-Kirchhasel, 07407, Germany|Private Practice Rinaldi, Ulm, 89073, Germany|Private Practice Woerth, Wiesbaden, 65189, Germany|Klinikverbund St. Antonius und St. Josef GmbH, Wuppertal, 42105, Germany|Rheuma Praxis Barmen Dres. med. Demirel / Hruschka, Wuppertal, 42285, Germany|Private Practice Fricke-Wagner, Zwickau, 08056, Germany|Private Practice Alliger, Zwiesel, 94227, Germany Less << | |
NCT05431283 | Ulcerative Colitis|Spondyloart... More >>hropathy Less << | UNKNOWN | 2023-12-31 | IBD Unit, Department of Intern... More >>al Medicine, "Villa Sofia-Cervello" Hospital, Palermo, Italy Less << | |
NCT04721821 | Arthritis Rheumatoid | COMPLETED | 2021-11-29 | Pfizer, New York, New York, 10... More >>017, United States Less << | |
NCT02312882 | Alopecia Areata|Alopecia Total... More >>is|Alopecia Universalis Less << | COMPLETED | 2025-08-15 | Stanford University, Stanford,... More >> California, 94305, United States Less << | |
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Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.20mL 0.64mL 0.32mL |
16.01mL 3.20mL 1.60mL |
32.01mL 6.40mL 3.20mL |