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Chemical Structure| 1394011-91-6 Chemical Structure| 1394011-91-6

Structure of UC2288
CAS No.: 1394011-91-6

Chemical Structure| 1394011-91-6

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UC2288 is a novel p21-attenuating reagent with cell permeability and oral activity (having relatively selective activity against p21), synthesized based on the structure of sorafenib. UC2288 downregulates the expression of p21 mRNA without relying on p53, reducing the level of p21 protein, with minimal impact on the stability of the p21 protein.

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Product Details of UC2288

CAS No. :1394011-91-6
Formula : C20H18ClF6N3O2
M.W : 481.82
SMILES Code : O=C(N[C@H]1CC[C@H](OC2=NC=C(C(F)(F)F)C=C2)CC1)NC3=CC=C(Cl)C(C(F)(F)F)=C3
MDL No. :MFCD28139634
InChI Key :ISPSOOYSNVVMMB-UHFFFAOYSA-N
Pubchem ID :60196635

Safety of UC2288

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.08mL

0.42mL

0.21mL

10.38mL

2.08mL

1.04mL

20.75mL

4.15mL

2.08mL

 

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