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Chemical Structure| 249296-44-4 Chemical Structure| 249296-44-4

Structure of Varenicline
CAS No.: 249296-44-4

Chemical Structure| 249296-44-4

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Varenicline is a selective α4β2 nicotinic receptor partial agonist and it stimulates nicotine receptors more weakly than nicotine itself does.

Synonyms: CP 526555

4.5 *For Research Use Only !

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Product Details of Varenicline

CAS No. :249296-44-4
Formula : C13H13N3
M.W : 211.26
SMILES Code : C12=C(C=C3N=CC=NC3=C2)C4CC1CNC4
Synonyms :
CP 526555
MDL No. :MFCD22208547
InChI Key :JQSHBVHOMNKWFT-UHFFFAOYSA-N
Pubchem ID :170361

Safety of Varenicline

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H319-H372-H410
Precautionary Statements:P273-P301+P312+P330-P305+P351+P338-P314
Class:9
UN#:3077
Packing Group:

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00596882 Smoking Cessation Phase 4 Completed - United States, Pennsylvania ... More >> Transdisciplinary Tobacco Use Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT02941718 Nicotine Dependence Phase 3 Active, not recruiting February 2019 United States, Delaware ... More >> University of Delaware Newark, Delaware, United States, 19713 Less <<
NCT01630161 Smoking Cessation Not Applicable Active, not recruiting June 2019 United States, Florida ... More >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Less <<
NCT00818207 Smoking Cessation ... More >> Insurance Coverage Less << Phase 4 Completed - -
NCT00818207 - Completed - -
NCT02493270 Periodontitis Not Applicable Completed - -
NCT01401569 Smoking Cessation ... More >> Depression Less << Phase 3 Terminated(Difficulties for re... More >>cruiting patients) Less << - France ... More >> University Hospital Montpellier, France, 34090 Less <<
NCT01566097 Cigarette Smoking ... More >> Tobacco Use Disorder Nicotine Dependence Smoking Cessation Less << Not Applicable Unknown July 2015 Korea, Republic of ... More >> Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Less <<
NCT01299896 Smoking Smoki... More >>ng Cessation Less << Not Applicable Completed - United States, Pennsylvania ... More >> VA Pittsburgh Healthcare System Pittsburgh, Pennsylvania, United States, 15206 Less <<
NCT01299896 - Completed - -
NCT00587353 Tobacco Use Disorder Phase 2 Completed - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT03670316 HIV AIDS ... More >> Smoking Cessation Less << Phase 4 Not yet recruiting July 1, 2023 United States, Alabama ... More >> University of Alabama, Birmingham Not yet recruiting Birmingham, Alabama, United States, 35209 Contact: Keith Chichester, B.A.    205-975-7809    krc80@uab.edu    Contact: Michelle Sisson, M.A.    205-975-7809    msisson2@uab.edu    Principal Investigator: Karen Cropsey, Psy.D. Less <<
NCT00933595 Pulmonary Complications ... More >> HIV Infections Less << Not Applicable Completed - United States, Ohio ... More >> Ohio State University Columbus, Ohio, United States, 43210 Less <<
NCT01083654 Smoking Not Applicable Completed - United States, Wisconsin ... More >> Menominee Tribal Clinic Keshena, Wisconsin, United States, 54135-0970 Less <<
NCT01083654 - Completed - -
NCT02994082 Smokeless Tobacco ... More >> Nicotine Dependence Less << Not Applicable Enrolling by invitation May 2020 United States, Iowa ... More >> Iowa City VA Healthcare System Iowa City, Iowa, United States, 52246 Less <<
NCT00754299 - Withdrawn(Study could not get ... More >>funding; research never initiated.) Less << October 2012 United States, Pennsylvania ... More >> The Milton S. Hershey Medical Center Hershey, Pennsylvania, United States, 17033 Less <<
NCT03077945 Smoking, Cigarette ... More >> Smoking Cessation Stress Stress, Emotional Stress Reaction Less << Not Applicable Completed - United States, New Jersey ... More >> Institute for Health, Health Care Policy and Aging Research New Brunswick, New Jersey, United States, 08901 Less <<
NCT01495689 Smoking Cessation Not Applicable Completed - Canada, Ontario ... More >> The Ottawa Hospital, General Campus Ottawa, Ontario, Canada, K1H8L6 Less <<
NCT01495689 - Completed - -
NCT01892813 Nicotine Dependence ... More >> Tobacco Use Less << Phase 3 Active, not recruiting January 2018 United States, Iowa ... More >> Iowa City VA Healthcare System Iowa City, Iowa, United States, 52246 Less <<
NCT01176383 Smoking Cessation Not Applicable Completed - United Kingdom ... More >> The Integrated Care Partnership The Old Cottage Hospital Alexandra Road, Epsom, Surrey, United Kingdom, KT17 4BL Less <<
NCT01859364 - Withdrawn March 1, 2023 -
NCT01526005 - Completed - United States, California ... More >> West Los Angeles Veterans Affairs Medical Center Los Angeles, California, United States, 90073 Less <<
NCT01399866 Smoking Cessation Phase 3 Completed - United States, Massachusetts ... More >> Massachusetts General Hospital - Center For Addiction Medicine Boston, Massachusetts, United States, 02114 Less <<
NCT01399866 - Completed - -
NCT03108651 Explore Successful Method to Q... More >>uit Smoking Less << Not Applicable Recruiting March 31, 2019 Taiwan ... More >> Syed Abdul Shabbir Recruiting Taipei, Taiwan, 11031 Contact: Syed Abdul Shabbir, PhD    +886 266382736 ext 1514    drshabbir@tmu.edu.tw    Sub-Investigator: Wei-Li Jeng, MD          Sub-Investigator: Hao-Yi Fang, PhD          Sub-Investigator: Chien-Tien Su, MD Less <<
NCT01156610 Smoking Smoki... More >>ng Cessation Less << Not Applicable Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02110 Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Less <<
NCT03612895 Smoking, Tobacco Not Applicable Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT01080092 Smoking Cessation Phase 2 Completed - Belgium ... More >> University Hospital Ghent Ghent, Belgium Less <<
NCT01592695 Cigarette Smoking Phase 2 Completed - United States, Iowa ... More >> Iowa City VA Health Care System Iowa City, Iowa, United States, 52246 Less <<
NCT01592695 - Completed - -
NCT03156660 Weight Change, Body ... More >> Smoking Cessation Less << Not Applicable Recruiting July 2021 United States, Tennessee ... More >> University of Tennessee Health Science Center Recruiting Memphis, Tennessee, United States, 38105 Contact: Study Coordinator    901-448-2000    fitquit@uthsc.edu Less <<
NCT01250301 Smoking Cessation ... More >> Tobacco Dependence Less << Not Applicable Completed - United Kingdom ... More >> Tobacco Dependence Research Unit London, United Kingdom, E1 2JH Less <<
NCT02585024 Smoking Cessation Phase 1 Recruiting March 2018 New Zealand ... More >> Soo Hee Jeong Recruiting Auckland, New Zealand, 1072 Contact: Soo Hee Jeong, PhD       s.jeong@auckland.ac.nz    Contact: Malcolm Tingle, PhD       m.tingle@auckland.ac.nz Less <<
NCT01850589 Smoking Cessation Not Applicable Terminated(Use of bupropion wi... More >>th counseling works better to help patients quit smoking.) Less << - United States, New York ... More >> Staten Island University Hospital Staten Island, New York, United States, 10305 Less <<
NCT01850589 - Terminated(Use of bupropion wi... More >>th counseling works better to help patients quit smoking.) Less << - -
NCT01350011 Tobacco Dependence Phase 3 Completed - United States, California ... More >> Behavioral Health Access Center San Francisco, California, United States, 94103 Less <<
NCT00962988 Cerebrovascular Disorders ... More >> Smoking Cessation Less << Phase 4 Completed - Canada, Ontario ... More >> Hamilton Health Sciences -Stroke Prevention Clinic Hamilton, Ontario, Canada, L8L 2X2 The Ottawa Hospital - Stroke Prevention Clinic Ottawa, Ontario, Canada, K1Y 4E9 Less <<
NCT02328794 Smoking Cessation Not Applicable Completed - United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01404546 Stroke Not Applicable Completed - Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y4W7 Less <<
NCT01691105 - Completed - -
NCT02424188 Tobacco Smoking in Persons Wit... More >>h Serious Mental Illness, Weight Management, Physical Activity Less << Not Applicable Recruiting June 2019 United States, Maryland ... More >> Johns Hopkins Recruiting Baltimore, Maryland, United States, 21287 Contact: Joseph Gennusa, PhD    410-218-1130    jgennus1@jhmi.edu Less <<
NCT01243203 Smoking Not Applicable Completed - Canada, Ontario ... More >> University Health Network, Department of Anesthesai Toronto, Ontario, Canada, M5T2S8 Less <<
NCT02195739 - Unknown December 2014 United Kingdom ... More >> Research in Real Life Ltd Cambridge, United Kingdom, CB24 3BA Less <<
NCT02635919 Nicotine Dependence Not Applicable Recruiting November 2018 United States, North Carolina ... More >> Duke Health Behavior Neuroscience Research Lab Recruiting Durham, North Carolina, United States, 27705 Less <<
NCT01691105 Tobacco Use Cessation ... More >> Smoking Cessation Smoking Tobacco Use Disorder Less << Not Applicable Completed - United States, Connecticut ... More >> Yale University New Haven, Connecticut, United States, 06510 Less <<
NCT01177176 Cigarette Smoking Not Applicable Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT01321944 Tobacco Dependence Not Applicable Completed - United States, Massachusetts ... More >> Revere Health Center Revere, Massachusetts, United States Less <<
NCT01714323 - Completed - -
NCT01871506 Smoking Cessation Not Applicable Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, New York Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Less <<
NCT01935505 - Unknown December 2018 -
NCT03521141 Tobacco Use Cessation Phase 2 Phase 3 Active, not recruiting August 1, 2019 United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37203 Less <<
NCT01714323 Cigarette Smoking ... More >> Tobacco Smoking Tobacco Use Disorder Less << Not Applicable Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 North Shore Medical Center Salem, Massachusetts, United States, 01970 United States, Pennsylvania University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT02048917 Lung Cancer H... More >>ead and Neck Cancer Less << Not Applicable Recruiting December 31, 2018 United States, Kentucky ... More >> King's Daughters Medical Center Recruiting Ashland, Kentucky, United States, 41101 Contact: Sherry Davis, RN    606-408-1636    Sherry.davis@kdmc.kdhs.us    Hardin Memorial Health Cancer Care Center Recruiting Elizabethtown, Kentucky, United States, 42701 Contact: Diane Drobny, RN    270-234-3250    ddrobny@hmh.net    ARH Cancer Center Recruiting Hazard, Kentucky, United States, 41701 Contact: Vicky Boggs, RN    606-487-7907    viboggs@arh.org    University Of Kentucky, Markey Cancer Center Recruiting Lexington, Kentucky, United States, 40536 Principal Investigator: Joseph Valentino, MD          University of Louisville, James Graham Brown Cancer Center Recruiting Louisville, Kentucky, United States, 40202 Contact: Jennifer Schoenbachler, RN    502-217-5229    jennifer.schoenbachler@louisville.edu    Contact: David Figg    (502) 562-4006    david.figg.1@louisville.edu    St. Claire Regional Medical Center Recruiting Morehead, Kentucky, United States, 40351 Contact: Mary Horsley, RN    606-783-6476    MAHorsley@st-claire.org    Owensboro Health Recruiting Owensboro, Kentucky, United States, 42303 Contact: Judy Strobel, RN    270-691-8094    Judith.Strobel@owensborohealth.org    United States, West Virginia St. Mary's Medical Center Recruiting Huntington, West Virginia, United States, 25702 Contact: Beverly Smith, RN    304-526-1807 Less <<
NCT01320462 Smoking Not Applicable Completed - Canada, Ontario ... More >> Toronto Western Hospital, Department of Aneshtesia Toronto, Ontario, Canada, M5T2S8 Mount Sinai Hospital, Department of Anesthesia Toronto, Ontario, Canada Less <<
NCT01553084 Smoking Cessation ... More >> Smoking Nicotine Dependence Less << Phase 4 Active, not recruiting January 2019 United States, Wisconsin ... More >> University of Wisconsin Center for Tobacco Research and Intervention, School of Medicine and Public Health Madison, Wisconsin, United States, 53711 University of Wisconsin Center for Tobacco Research and Intervention, School of Medicine and Public Health Milwaukee, Wisconsin, United States, 53233 Less <<
NCT02562521 - Completed - -
NCT01574703 Smoking Cessation Phase 4 Completed - -
NCT02562521 Smoking Cessation Phase 4 Completed - United States, Connecticut ... More >> Yale University New Haven, Connecticut, United States, 06511 Less <<
NCT02460900 Smoking HIV Phase 3 Recruiting July 2020 United States, Maryland ... More >> University of Maryland Medical Center, Midtown Campus Recruiting Baltimore, Maryland, United States, 21210 Contact: Wendy Potts, MS    410-706-2490    wpotts@som.umaryland.edu Less <<
NCT00139750 Smoking Cessation Phase 2 Completed - Japan ... More >> Pfizer Investigational Site Noda, Chiba, Japan Pfizer Investigational Site Sapporo, Hokkaido, Japan Pfizer Investigational Site Yokohama, Kanagawa, Japan Pfizer Investigational Site Beppu-shi, Oita-ken, Japan Pfizer Investigational Site Toyonaka, Osaka, Japan Pfizer Investigational Site Tosu, Saga, Japan Pfizer Investigational Site Hamamatsu, Shizuoka, Japan Pfizer Investigational Site Edogawa-ku, Tokyo, Japan Pfizer Investigational Site Minato-ku, Tokyo, Japan Pfizer Investigational Site Musashino, Tokyo, Japan Pfizer Investigational Site Setagaya-ku, Tokyo, Japan Pfizer Investigational Site Shinagawa-ku, Tokyo, Japan Pfizer Investigational Site Toshima-ku, Tokyo, Japan Pfizer Investigational Site Fukuoka, Japan Pfizer Investigational Site Ohita, Japan Less <<
NCT00664404 Smoking Phase 3 Completed - United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00150228 Smoking Cessation Phase 2 Completed - United States, Kentucky ... More >> Pfizer Investigational Site Lexington, Kentucky, United States United States, Minnesota Pfizer Investigational Site Albert Lea, Minnesota, United States Pfizer Investigational Site Rochester, Minnesota, United States United States, Pennsylvania Pfizer Investigational Site Philadelphia, Pennsylvania, United States United States, Rhode Island Pfizer Investigational Site Providence, Rhode Island, United States United States, Wisconsin Pfizer Investigational Site La Crosse, Wisconsin, United States Pfizer Investigational Site Madison, Wisconsin, United States Less <<
NCT01574703 - Completed - -
NCT00150254 Smoking Cessation Phase 2 Completed - United States, California ... More >> Pfizer Investigational Site Los Angeles, California, United States Pfizer Investigational Site San Bernardino, California, United States Pfizer Investigational Site Upland, California, United States Pfizer Investigational Site West Covina, California, United States United States, Connecticut Pfizer Investigational Site Farmington, Connecticut, United States United States, Florida Pfizer Investigational Site Jackson, Florida, United States United States, Kentucky Pfizer Investigational Site Lexington, Kentucky, United States United States, Louisiana Pfizer Investigational Site New Orleans, Louisiana, United States United States, Mississippi Pfizer Investigational Site Jackson, Mississippi, United States United States, Nebraska Pfizer Investigational Site Omaha, Nebraska, United States United States, Ohio Pfizer Investigational Site Cincinnati, Ohio, United States United States, Oregon Pfizer Investigational Site Portland, Oregon, United States United States, Texas Pfizer Investigational Site Houston, Texas, United States Less <<
NCT01474265 Smoking Cessation Phase 4 Completed - Germany ... More >> University Medical Center Goettingen, Germany, 37075 Less <<
NCT01106456 Smoking Cessation Phase 3 Completed - United States, Kansas ... More >> University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Oklahoma University of Oklahoma College of Public Health Oklahoma City, Oklahoma, United States, 73104 Less <<
NCT02744417 Periodontitis Not Applicable Completed - -
NCT01106456 - Completed - -
NCT02582008 Current Smoker ... More >> Head and Neck Squamous Cell Carcinoma Hypopharyngeal Squamous Cell Carcinoma Laryngeal Squamous Cell Carcinoma Nasopharyngeal Carcinoma Oral Cavity Squamous Cell Carcinoma Oropharyngeal Squamous Cell Carcinoma Less << Early Phase 1 Recruiting January 2020 United States, North Carolina ... More >> Wake Forest University Health Sciences Recruiting Winston-Salem, North Carolina, United States, 27157 Contact: Mercedes Porosnicu    336-716-8664    mporosni@wakehealth.edu    Principal Investigator: Mercedes Porosnicu          United States, South Carolina Medical University of South Carolina Not yet recruiting Charleston, South Carolina, United States, 29425 Contact: Graham Warren    843-876-2295    warrengw@musc.edu    Principal Investigator: Graham Warren Less <<
NCT00894166 Smoking Cessation Phase 3 Completed - United States, North Carolina ... More >> Duke Center for Nicotine & Smoking Cessation Research Charlotte, Durham, Raleigh, Winston-Salem, North Carolina, United States Less <<
NCT02050308 Smoking Cessation Phase 3 Active, not recruiting March 2019 United States, Kansas ... More >> University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Montana Salish Kootenai College Pablo, Montana, United States, 59855 Less <<
NCT00894166 - Completed - -
NCT03553173 Smoking Cessation ... More >> Health Behavior Lifestyle-related Condition Less << Not Applicable Completed - -
NCT01330043 Smoking Cessation Phase 4 Completed - United States, California ... More >> Stanford University School of Medicine Stanford, California, United States, 94305 Less <<
NCT02797587 HIV Infection ... More >> Alcohol Use Smoking Less << Phase 2 Phase 3 Recruiting December 2020 Russian Federation ... More >> First St. Petersburg Pavlov State Medical University Recruiting St. Petersburg, Russian Federation, 197022 Contact: Evgeny Krupitsky, MD,PhD,DMdSc    +7-812-365-2217    kruenator@gmail.com Less <<
NCT02351167 Smoking Cessation Phase 4 Active, not recruiting December 1, 2019 United States, Missouri ... More >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 Less <<
NCT00150241 Smoking Cessation Phase 2 Completed - United States, California ... More >> Pfizer Investigational Site Los Angeles, California, United States United States, Connecticut Pfizer Investigational Site Farmington, Connecticut, United States United States, Minnesota Pfizer Investigational Site Minneapolis, Minnesota, United States United States, Nebraska Pfizer Investigational Site Omaha, Nebraska, United States United States, New York Pfizer Investigational Site New York, New York, United States United States, Oregon Pfizer Investigational Site Portland, Oregon, United States United States, West Virginia Pfizer Investigational Site Morgantown, West Virginia, United States Less <<
NCT01330043 - Completed - -
NCT00683280 Cigarette Smoking Not Applicable Completed - United States, Connecticut ... More >> University of Connecticut Health Center Farmington, Connecticut, United States, 06030-3944 Less <<
NCT01162239 Nicotine Dependence Phase 3 Unknown July 2017 United States, California ... More >> University of California San Francisco San Francisco, California, United States, 94143 Less <<
NCT01406223 - Completed - -
NCT01531049 Smoking Cessation ... More >> Smoking Habits Less << Phase 2 Phase 3 Completed - Finland ... More >> Lapland Central Hospital, Lapland Hospital District Rovaniemi, Finland, 96400 Less <<
NCT00921388 Nicotine Dependence ... More >> Smoking Cessation Less << Not Applicable Completed - United States, Connecticut ... More >> University of Connecticut Health Center Farmington, Connecticut, United States, 06030 United States, Minnesota University of Minnesota Minneapolis, Minnesota, United States, 55455 Less <<
NCT03227679 Tobacco Use T... More >>obacco Use Cessation Less << Not Applicable Completed - -
NCT02683161 Cigarette Smoking ... More >> Obesity Less << Phase 2 Terminated(Inability to adequa... More >>tely recruit participants during pre-post operative period.) Less << - United States, Maryland ... More >> Johns Hopkins Bayview Medical Center Baltimore, Maryland, United States, 21224 Less <<
NCT02683161 - Terminated(Inability to adequa... More >>tely recruit participants during pre-post operative period.) Less << - -
NCT01623505 Smoking Cessation ... More >> Psychiatric Illness Less << Phase 4 Completed - Canada, Ontario ... More >> University of Ottawa Heart Insitute - Prevention and Wellness Centre Ottawa, Ontario, Canada, K1Y 4W7 Less <<
NCT01406223 Nicotine Dependence Phase 3 Completed - United States, North Carolina ... More >> Duke Center for Nicotine and Smoking Cessation Research Durham, North Carolina, United States, 27705 Duke Center for Nicotine and Smoking Cessation Research Raleigh, North Carolina, United States, 27609 Less <<
NCT02856581 Lung Carcinoma Phase 3 Recruiting February 2022 -
NCT02551692 Cigarette Smoking Not Applicable Active, not recruiting October 2018 United States, North Carolina ... More >> Duke Medical Center Durham, North Carolina, United States, 27705 Less <<
NCT01560507 - Terminated(Low Recruitment) - -
NCT01098955 Head and Neck Cancer ... More >> Smoking Cessation Less << Early Phase 1 Active, not recruiting March 2019 United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT00580398 Lung Cancer Phase 1 Phase 2 Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT00580398 - Completed - -
NCT01560507 Cigarette Smoking ... More >> Nicotine Dependence Less << Phase 2 Phase 3 Terminated(Low Recruitment) - United States, North Carolina ... More >> Duke Center forSmoking Cessation Durham, North Carolina, United States, 27705 Duke Center for Smoking Cessation Raleigh, North Carolina, United States, 27609 Less <<
NCT00301145 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Not Applicable Completed - United States, California ... More >> SRI International Menlo Park, California, United States, 94025 United States, Washington Center for Health Studies Seattle, Washington, United States, 98101-1448 Free & Clear, Incorporated Seattle, Washington, United States, 98104 Less <<
NCT03507127 Tobacco Dependence Phase 2 Recruiting July 2020 United States, Rhode Island ... More >> Brown University, 121 South Main Street Recruiting Providence, Rhode Island, United States, 02912 Contact: Jennifer Tidey, Ph.D.    401-863-6418    Jennifer_Tidey@brown.edu    Principal Investigator: Jennifer Tidey, Ph.D. Less <<
NCT01800019 HIV Smoking C... More >>essation Less << Phase 3 Active, not recruiting January 2019 Canada, Ontario ... More >> The Ottawa Hospital Ottawa, Ontario, Canada, K1H 8L6 Less <<
NCT02367391 Nicotine Dependence, Cigarette... More >>s Less << Not Applicable Completed - United States, Pennsylvania ... More >> Penn State Milton S. Hershey Medical Center Hershey, Pennsylvania, United States, 17033 Less <<
NCT02233231 Asthma Phase 4 Completed - -
NCT01314001 Nicotine Addiction Phase 3 Completed - United States, New York ... More >> University at Buffalo - State University of New York Buffalo, New York, United States, 14260 United States, Pennsylvania Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Texas MD Anderson Cancer Center, University of Texas Houston, Texas, United States, 77230 Canada, Ontario Centre for Addiction and Mental Health, University of Toronto Toronto, Ontario, Canada, M5T1RH Less <<
NCT01314001 - Completed - -
NCT00507728 Tobacco Use Disorder ... More >> Smoking Cessation Less << Phase 2 Phase 3 Active, not recruiting December 1, 2020 United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT02367391 - Completed - -
NCT02723162 Nicotine Dependence, Cigarette... More >>s Less << Not Applicable Recruiting July 2020 United States, South Carolina ... More >> Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29403 Contact: Lori Ann Ueberroth    843-792-8220    ueberro@musc.edu    Contact: Eichberg          Principal Investigator: Kevin Gray, MD Less <<
NCT03235505 Smoking Cessation ... More >> Electronic Cigarette Less << Phase 4 Recruiting December 31, 2020 Finland ... More >> Lapland Central Hospital Recruiting Rovaniemi, Finland, 96440 Contact: Tuula Toljamo, PhD    +358407218759    tuula.toljamo@lshp.fi Less <<
NCT00832806 Additional, Effective Methods ... More >>to Stop Smoking Less << Phase 1 Completed - Canada, British Columbia ... More >> Healthy Heart Program, St. Paul's Hospital Vancouver, British Columbia, Canada, V6Z 1Y6 Less <<
NCT00937508 Smoking Phase 4 Unknown June 2011 Canada, Ontario ... More >> Toronto Western Hospital Recruiting Toronto, Ontario, Canada, M5T 2S8 Contact: Frances Chung, FRCPC    416-603-5800    frances.chung@uhn.on.ca    Principal Investigator: Frances Chung, FRCPC Less <<
NCT00701896 Smoking HIV I... More >>nfections Less << Not Applicable Completed - United States, Ohio ... More >> The Ohio State University Columbus, Ohio, United States, 43210 Less <<
NCT01027754 Smoking Cessation ... More >> Substance-Related Disorders Less << Phase 4 Unknown - United States, New York ... More >> Albert Einstein College of Medicine of Yeshiva University Bronx, New York, United States, 10467 Less <<
NCT02681510 Smoking Phase 4 Completed - United States, Wisconsin ... More >> UW CTRI Madison, Wisconsin, United States, 53711 Less <<
NCT02681510 - Completed - -
NCT02307045 Smoking Cessation Phase 4 Unknown February 2015 Greece ... More >> ''Attikon'' University General Hospital Recruiting Haidari, Athens, Attiki, Greece, 12462 Principal Investigator: Ignatios Ikonomidis, MD Less <<
NCT02501265 Nicotine Dependence Phase 2 Recruiting December 2020 United States, North Carolina ... More >> Duke Center for Smoking Cessation Recruiting Durham, North Carolina, United States, 27705 Contact: Jed Rose, Ph.D.    919-668-5055 Less <<
NCT03176784 Tobacco Dependence Phase 4 Recruiting December 1, 2022 United States, Wisconsin ... More >> UW Center For Tobacco Research and Intervention Recruiting Madison, Wisconsin, United States, 53711 Contact: Madeline Oguss, BA    608-265-5552    mkoguss@ctri.wisc.edu    UW Center for Tobacco Research and Intervention Recruiting Milwaukee, Wisconsin, United States, 53233 Contact: Madeline Oguss, BA    608-265-5552    mkoguss@ctri.wisc.edu Less <<
NCT02888444 Chronic Obstructive Pulmonary ... More >>Disease Smoking Cessation Less << Phase 3 Recruiting April 2019 New Zealand ... More >> National Institute for Health Innovation, University of Auckland Recruiting Auckland, New Zealand Contact: Natalie Walker, PhD    64 9 923 9884    n.walker@auckland.ac.nz Less <<
NCT00931021 Smoking Cessation Early Phase 1 Terminated - United States, Connecticut ... More >> Yale University School of Medicine New Haven, Connecticut, United States, 06511 Less <<
NCT02106637 Acute Coronary Syndrome ... More >> Smoking Cessation Less << Not Applicable Recruiting December 2018 Israel ... More >> Sheba Medical Center Recruiting Ramat Gan, Israel, 5262179 Contact: Ilan Goldenberg, MD    972-5302848    ilan.goldenberg@sheba.health.gov.il Less <<
NCT00781755 Tobacco Use Disorder Phase 4 Withdrawn(Study design was alt... More >>ered such that a treatment component was removed through the VA IRB. We did not and will not begin this clinical trial.) Less << - United States, Massachusetts ... More >> VA Boston Healthcare System Brockton Medical Center Brockton, Massachusetts, United States, 02301 Less <<
NCT00679237 Coronary Heart Disease Not Applicable Active, not recruiting December 2024 Norway ... More >> Sorlandet Hospital Arendal, Norway Less <<
NCT02601521 Smoking Cessation ... More >> Tobacco Use Disorder Less << Not Applicable Recruiting December 2018 United States, Massachusetts ... More >> Massachusetts General Hospital Recruiting Boston, Massachusetts, United States, 02114 Contact: Jennifer Kulesa-Kelley, RN    781-433-3041    jkelley4@partners.org    Principal Investigator: Nancy Rigotti, MD Less <<
NCT02601599 Smoking Not Applicable Completed - Ireland ... More >> Connolly Hospital Blanchardstown Dublin, Ireland Less <<
NCT01974063 - Terminated(Grant Ended) - United States, New York ... More >> Rockefeller University Hospital New York, New York, United States, 10065 Weill Cornell Medical College and Weill Cornell Medical Center, Department of Genetic Medicine New York, New York, United States, 10065 Less <<
NCT03691350 Cigarette Smoker ... More >> Current Every Day Smoker Less << Early Phase 1 Recruiting April 1, 2020 United States, Ohio ... More >> Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Sarah Reisinger, MPH, MCHES    614-366-4542    Sarah.Reisinger@osumc.edu    Principal Investigator: Peter G. Shields, MD Less <<
NCT03059940 Smoking Cessation Early Phase 1 Recruiting June 2023 United States, Texas ... More >> University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact       pcinciri@mdanderson.org Less <<
NCT03452371 Smoking Cessation Not Applicable Enrolling by invitation September 2019 United States, Massachusetts ... More >> Boston Medical Center Boston, Massachusetts, United States, 02118 Less <<
NCT01489579 Tobacco Use Cessation Not Applicable Completed - United States, Colorado ... More >> Clinical Pharmacy Specialist, Clinical Pharmacy Cardiac Risk Service - Kaiser Permanente of Colorado Aurora, Colorado, United States, 80011 Less <<
NCT03229356 Smoking Cessation Not Applicable Enrolling by invitation June 17, 2019 United States, Maryland ... More >> Johns Hopkins Community Physcians Baltimore, Maryland, United States, 21211 Less <<
NCT01290445 - Completed - -
NCT00621777 Schizophrenia ... More >> Schizoaffective Disorder Bipolar Disorder Smoking Less << Phase 4 Completed - United States, Alabama ... More >> University of Alabama Psychology Clinic Birmingham, Alabama, United States, 35233 United States, Indiana Centerstone Research Institute Bloomington, Indiana, United States, 47401 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Massachusetts Mental Health Center Boston, Massachusetts, United States, 02115 United States, Michigan Touchstone Innovare Grand Rapids, Michigan, United States, 49503 United States, Minnesota University of Minnesota Psychological Clinic Minneapolis, Minnesota, United States, 55454 United States, New Hampshire West Central Behavioral Health Claremont, New Hampshire, United States, 03743 Riverbend Community Mental Health Center Concord, New Hampshire, United States, 03302 The Mental Health Center of Greater Manchester Manchester, New Hampshire, United States, 03103 Community Council of Nashua Nashua, New Hampshire, United States, 03063 Less <<
NCT00621777 - Completed - -
NCT00749944 Smoking Cessation Phase 4 Completed - United States, Texas ... More >> Pfizer Investigational Site Austin, Texas, United States, 78759 Pfizer Investigational Site San Antonio, Texas, United States, 78217 Less <<
NCT01771627 Tobacco Use Disorder Not Applicable Completed - United States, New York ... More >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263 Less <<
NCT00813917 Nicotine Dependence Not Applicable Completed - United States, Minnesota ... More >> Nicotine Research Program Rochester, Minnesota, United States, 55905 Less <<
NCT01078298 Smoking Cessation ... More >> Depression Less << Phase 4 Completed - -
NCT00492349 Schizophrenia ... More >> Schizoaffective Disorder Schizophreniform Disorder Less << Phase 4 Completed - United States, Maryland ... More >> UMB School of Medicine Baltimore, Maryland, United States, 21201 University of Maryland Medical System Baltimore, Maryland, United States, 21201 Maryland Psychiatric Research Center Baltimore, Maryland, United States, 21228 Less <<
NCT01532232 - Terminated(Lack of accrual) - United States, New York ... More >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Less <<
NCT00749944 - Completed - -
NCT00492349 - Completed - -
NCT00794365 - Completed - -
NCT00794365 - Completed - -
NCT03557294 Tobacco Dependence ... More >> Withdrawal Symptoms Smoking Cessation Less << Phase 4 Recruiting June 2022 United States, Arizona ... More >> Arizona State University Not yet recruiting Phoenix, Arizona, United States, 85004 Contact: Scott J. Leischow, PhD    602-827-2271    scott.leischow@asu.edu    United States, California Los Angeles Clinical Trials Recruiting Burbank, California, United States, 91505 Contact: Mitchell Nides, PhD    818-526-7645    mnides@laclinicaltrials.com Less <<
NCT00673595 Smoking Not Applicable Terminated(Difficulty with rec... More >>ruiting sujects and subjects complying with the protocol) Less << - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT00673595 - Terminated(Difficulty with rec... More >>ruiting sujects and subjects complying with the protocol) Less << - -
NCT01078298 - Completed - -
NCT01111149 - Completed - -
NCT01524627 Nicotine Dependence Phase 2 Completed - United States, Pennsylvania ... More >> University of Pennsylvania Addiction Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT00813917 - Completed - -
NCT01524627 - Completed - -
NCT00918307 HIV Infections ... More >> Tobacco Dependence Less << Phase 3 Completed - France ... More >> CHU de Bordeaux Bordeaux, France, 33075 Less <<
NCT01111149 Schizophrenia ... More >> Smoking Cessation Less << Phase 2 Completed - United States, Minnesota ... More >> University of Minnesota, University of Minnesota Medical Center Minneapolis, Minnesota, United States, 55455 Less <<
NCT03069768 Nicotine Dependence Phase 1 Withdrawn(Unable to obtain var... More >>enicline to provide to participants) Less << June 2019 United States, North Carolina ... More >> Duke Health Behavior Neuroscience Research Lab Durham, North Carolina, United States, 27705 Less <<
NCT03362099 Smoking Cessation ... More >> Genetic Predisposition Less << Not Applicable Recruiting March 1, 2022 Brazil ... More >> Ambulatório de Tratamento Tabagismo - Incor HCFMUSP Recruiting São Paulo, Brazil, 05403000 Less <<
NCT02378714 Nicotine Dependence ... More >> Major Depressive Disorder Less << Phase 4 Recruiting August 2020 United States, Illinois ... More >> Northwestern University Recruiting Chicago, Illinois, United States, 60611 Contact: Amanda R Mathew, Ph.D.    312-503-3040    amanda.mathew@northwestern.edu    United States, Pennsylvania University of Pennsylvania Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Su Fen Lubitz    215-746-4040    lubitz@mail.med.upenn.edu Less <<
NCT00959972 Coronary Heart Disease Phase 4 Completed - Canada, Ontario ... More >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y 4W7 Less <<
NCT00934024 - Completed - -
NCT01093365 Schizophrenia ... More >> Schizoaffective Disorder Less << Phase 2 Completed - Canada, Ontario ... More >> Centre for Addiction and Mental Health (33 Russell street) Toronto, Ontario, Canada, M5S 2S1 Less <<
NCT00934024 Nicotine Dependence Not Applicable Completed - United States, South Carolina ... More >> Medical University of South Carolina Charleston, South Carolina, United States, 29425 Less <<
NCT02933372 Parkinson's Disease Phase 2 Enrolling by invitation April 2020 -
NCT00595868 Tobacco Use Disorder ... More >> Tobacco Use Cessation Nicotine Dependence Less << Phase 2 Completed - United States, Nebraska ... More >> Nebraska Medical Center Omaha, Nebraska, United States, 68198 United States, Vermont University of Vermont Burlington, Vermont, United States, 05401 Less <<
NCT00595868 - Completed - -
NCT00747643 Tobacco Dependence Not Applicable Completed - United States, Florida ... More >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Less <<
NCT00747643 - Completed - -
NCT00502216 - Completed - -
NCT00702793 Schizophrenia ... More >> Schizoaffective Psychosis Less << Phase 4 Withdrawn(No participants enro... More >>lled) Less << - -
NCT00502216 Smoking Nicot... More >>ine Dependence Less << Phase 1 Phase 2 Completed - United States, Connecticut ... More >> Yale University School of Medicine Substance Abuse Treatment Unit New Haven, Connecticut, United States, 06511 Less <<
NCT01710137 Nicotine Dependence Phase 3 Completed - United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT00772941 - Completed - -
NCT01184664 Tobacco Dependence ... More >> Smoking Cessation Less << Phase 3 Completed - United Kingdom ... More >> Tobacco Dependence Research and Treatment Unit London, United Kingdom, E1 2JH Tobacco Dependence Research Unit London, United Kingdom, E1 2JH Less <<
NCT00835900 Smoking Cessation Phase 2 Completed - United States, New York ... More >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263 Less <<
NCT01169610 - Terminated - -
NCT00873535 Tobacco Dependence ... More >> Alcohol Dependence Less << Not Applicable Completed - Canada, Ontario ... More >> Centre for Addiction and Mental Health Toronto, Ontario, Canada, M5S 2S1 Less <<
NCT01169610 Alcoholism Ni... More >>cotine Dependence Less << Phase 3 Terminated - United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less <<
NCT00835900 - Completed - -
NCT00772941 - Completed - -
NCT00802919 - Completed - -
NCT01206010 Tobacco Dependence ... More >> Smoking Cessation Less << Phase 3 Completed - United Kingdom ... More >> Tobacco Dependence Research and Treatment Unit London, United Kingdom, E1 2JH Less <<
NCT00727103 Schizophrenia ... More >> Schizoaffective Disorder Alcohol Dependence Nicotine Dependence Less << Phase 4 Terminated(Slow recruitment, h... More >>igh drop-out rate in both arms) Less << - United States, New York ... More >> SUNY Upstate Medical University Syracuse, New York, United States, 13210 Less <<
NCT00802919 Schizophrenia ... More >> Cigarette Smoking Less << Phase 4 Completed - United States, New York ... More >> Manhattan Psychatirc Center New York, New York, United States, 10035 Nathan Kline Insitute for Psychiatric Research Orangeburg, New York, United States, 10962 China Peking University Institute of Mental Health Beijing, China, 100191 Israel The Division of Psychiatry, Chaim Sheba Medical Center Tel Hashomer, Israel, 52621 Less <<
NCT00455650 Cognition in Schizophrenia Not Applicable Completed - United States, Massachusetts ... More >> Freedom Trail Clinic, Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT00455650 - Completed - -
NCT01098305 - Completed - -
NCT02575183 Nicotine Dependence Phase 4 Recruiting December 1, 2018 Lebanon ... More >> American University of Beirut Medical Center Recruiting Beirut, Lebanon, 1107-2020 Contact: Hassan Chami, M.D    009611350000 ext 5303    hchami@aub.edu.lb    Contact: Nour Houshaimi, M.D    009611350000 ext 5923    nourhoushaimi@gmail.com    American University of Beirut Medical Center Not yet recruiting Beirut, Lebanon Contact: Hassan Chami, MD, MSc    961 1 374 374 ext 5303    hchami@aub.edu.lb    Principal Investigator: Hassan Chami, MD, MSc          Sub-Investigator: Farid Talih, MD          Sub-Investigator: Monique Chaaya, Phd          Sub-Investigator: Christine Weir Abbyad, Phd Less <<
NCT01656083 - Unknown December 2012 Germany ... More >> MicroCO/SmokeCheck Recruiting Beijing, Germany, 100029 Contact: xu jing, faculty    008610-84205204       Contact: liu chao wu, master    008610-84206185       Sub-Investigator: chen xin, MD          Sub-Investigator: liu chao wu, MD          Sub-Investigator: liu chao wu, Master          Sub-Investigator: su nan, MD          Principal Investigator: yu hong xia, MD          Sub-Investigator: lin jiang tao, MD          Sub-Investigator: wang tao, MD          Principal Investigator: yuan jiang, PHD          Principal Investigator: YAN YANG, PHD Less <<
NCT00774605 Smoking Cessation Phase 1 Completed - United States, Connecticut ... More >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 Less <<
NCT01413516 - Completed - -
NCT01413516 Smoking Cessation Phase 2 Completed - United States, California ... More >> Stanford Hospital and Clinics Stanford, California, United States, 94305 Less <<
NCT01098305 Tobacco Use Disorder Phase 2 Completed - India ... More >> All India Institute of Medical Research New Dehli, India Less <<
NCT00731562 Pharmacokinetics ... More >> Bioavailability Smoking Cessation Less << Phase 1 Completed - United States, Minnesota ... More >> Pfizer Investigational Site East Grand Forks, Minnesota, United States, 56721 United States, North Dakota Pfizer Investigational Site Fargo, North Dakota, United States, 58104 Less <<
NCT00789074 Tobacco Dependence ... More >> Smoking Cessation Less << Phase 3 Completed - United Kingdom ... More >> Tobacco Dependence Research and Treatment Unit London, United Kingdom, E1 2JH Less <<
NCT00567320 Cocaine Dependence ... More >> Nicotine Dependence Less << Not Applicable Completed - United States, Connecticut ... More >> Veterans Hopsital West Haven, Connecticut, United States, 06516 Less <<
NCT02698215 Nicotine Dependence ... More >> Alcohol Use Disorder Less << Phase 2 Recruiting June 2019 United States, California ... More >> UCLA Addictions Laboratory Recruiting Los Angeles, California, United States, 90095 Contact: Jessica Jenkins, MA    310-206-6756    raylab@psych.ucla.edu    Principal Investigator: Lara Ray, PhD          Sub-Investigator: Adam Levanthal, PhD          Sub-Investigator: Karen Miotto, MD          Sub-Investigator: Keith Heinzerling, MD          Sub-Investigator: Gang Li, PhD Less <<
NCT00567320 - Completed - -
NCT00889720 Smoking Cessation Phase 4 Completed - France ... More >> Pfizer Investigational Site Paris Cedex 13, France, 75651 Italy Pfizer Investigational Site Pisa, Italy, 56124 Less <<
NCT01143857 Cocaine Dependence Phase 2 Withdrawn - United States, Pennsylvania ... More >> University of Pennsylvania, Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01756885 Nicotine Dependence Phase 3 Active, not recruiting October 2018 United States, Illinois ... More >> Northwestern University Chicago, Illinois, United States, 60611 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT00789074 - Completed - -
NCT01553136 Alcoholism Al... More >>cohol Abuse Smoking Alcohol Drinking Less << Phase 2 Completed - United States, Connecticut ... More >> Connecticut Mental Health Center - Substance Abuse Treatment Unit New Haven, Connecticut, United States, 06511 United States, New York Parallax Center New York, New York, United States, 10016 Less <<
NCT01553136 - Completed - -
NCT00525837 - Completed - -
NCT00525837 Depressive Disorder ... More >> Smoking Less << Not Applicable Completed - United States, Rhode Island ... More >> Butler Hospital Providence, Rhode Island, United States, 02906 Less <<
NCT00889720 - Completed - -
NCT00523445 Schizophrenia Phase 3 Completed - Korea, Republic of ... More >> Dongrae Hospital Busan, Korea, Republic of, 609-370 Jamyeong Busan, Korea, Republic of, 612-827 Busan Paik Hospital Busan, Korea, Republic of, 614-735 Ahab Hospital BUsan, Korea, Republic of, 616-824 Dongseo hospital Masan, Korea, Republic of, 630-856 Less <<
NCT01011907 Substance Dependence Not Applicable Completed - United States, California ... More >> UCSF: Ernest Gallo Clinic and Research Center Emeryville, California, United States, 94608 Less <<
NCT01387425 Smoking Cessation ... More >> Diabetes Less << Not Applicable Completed - Italy ... More >> Centro per la Prevenzione e Cura del Tabagimso Catania, Italy, 95124 Centro per la Prevenzione eCura del Tabagimso Catania, Italy, 95124 Less <<
NCT01286584 Smoking Cessation ... More >> Alcohol Abuse Less << Phase 4 Completed - Canada, Ontario ... More >> Centre for Addiction and Mental Health, Nicotine Dependence Clinic Toronto, Ontario, Canada, M5T 1P7 Less <<
NCT00944554 - Completed - -
NCT00713479 Methamphetamine Addiction ... More >> Crystal Meth Addiction Amphetamine Addiction Less << Phase 1 Completed - United States, California ... More >> UCLA NPI Los Angeles, California, United States, 90095 Less <<
NCT01680887 Cocaine Dependence Phase 2 Active, not recruiting June 2018 United States, Pennsylvania ... More >> University of Pennsylvania Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01011907 - Completed - -
NCT01011829 Methamphetamine Dependence ... More >> Substance Abuse Methamphetamine Abuse Less << Phase 2 Completed - United States, California ... More >> UCLA Vine Street Clinic Los Angeles, California, United States, 90038 Less <<
NCT00944554 Recurrence Sm... More >>oking Cessation Substance-Related Disorders Less << Phase 4 Completed - United States, Maryland ... More >> Behavioral Pharmacology Research Unit Baltimore, Maryland, United States, 21224 Less <<
NCT01011829 - Completed - -
NCT01509547 Nicotine Dependence Phase 3 Completed - United States, South Carolina ... More >> Medical University of South Carolina Charleston, South Carolina, United States, 29425 Less <<
NCT01308671 Coronary Artery Disease Not Applicable Unknown April 2016 China ... More >> General Hospital of Chinese People's Armed Police Forces Recruiting Beijing, China, 100039 Contact: Hui Liang Liu, Doctor    86-01-88276531    lhl518@vip.sina.com    Contact: Yu Jie Wei, Master    86-01-88276707    weiyujie6980@sina.com    Principal Investigator: Hui Liang Liu, Doctor          Principal Investigator: Yu Jie Wei, Master          Sub-Investigator: Jie Sun, Master Less <<
NCT00713479 - Completed - -
NCT01444131 Tobacco Dependence Phase 2 Completed - South Africa ... More >> Respiratory Research Unit Cape Town, Western Cape, South Africa, 7505 Synopsis Research Cape Town, Western Cape, South Africa, 7700 UCT Lung Institute Cape Town, Western Cape, South Africa, 8000 Dr JA O'Brien Cape Town, Western Cape, South Africa, 8001 Dr AHH Brüning Gatesville / Cape Town, Western Cape, South Africa, 7764 Dr MS Abdool-Gaffar Amanzimtoti, South Africa, 4126 Dr C Smith Sandton, South Africa, 2010 Less <<
NCT01146613 - Completed - -
NCT00548470 Schizophrenia ... More >> Tobacco Use Disorder Nicotine Dependance Less << Phase 4 Completed - United States, New York ... More >> Manhattan Psychiatric Center New York, New York, United States, 10035 Less <<
NCT01146613 Alcoholism Phase 2 Completed - United States, Maryland ... More >> Johns Hopkins University School of Medicine Baltimore, Maryland, United States, 21224 United States, Massachusetts Boston Medical Center Boston, Massachusetts, United States, 02118 United States, New Hampshire Dartmouth Medical School Bedford, New Hampshire, United States, 03110 Dartmouth Medical School Hanover, New Hampshire, United States, 03755 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19103 United States, Virginia University of Virginia Charlottesville, Virginia, United States, 22911 University of Virginia Richmond, Virginia, United States, 23294 Less <<
NCT01013454 Smoking Cessation Phase 1 Completed - Belgium ... More >> Pfizer Investigational Site Bruxelles, Belgium, 1070 Less <<
NCT02634281 Smoking Cessation Phase 4 Unknown July 2018 Israel ... More >> Shaare Zedek Medical center Recruiting Jerusalem, Israel, 9103102 Contact: Abraham Bohadana, MD    9722772245141    abohadana@szmc.org.il Less <<
NCT02957786 Smoking Cessation Phase 3 Recruiting May 2019 New Zealand ... More >> National Institute for Health Innovation, University of Auckland Recruiting Auckland, North Island, New Zealand, 1072 Contact: Natalie Walker, PhD    64 9 373 7999    n.walker@auckland.ac.nz    Contact: Chris Bullen, PhD, MBChB    64 9 373 7999    c.bullen@auckland.ac.nz    Principal Investigator: Natalie Walker, PhD          Sub-Investigator: Chris Bullen, PhD;MBChB          Sub-Investigator: Joanne Barnes, PhD          Sub-Investigator: Barry Smith, PhD          Sub-Investigator: Subhash Pokhrel, PhD          Sub-Investigator: Varsha Parag, MSc (Hons) Less <<
NCT02859142 Smoking Cessation ... More >> Alcohol Drinking Less << Phase 4 Recruiting November 2019 United States, Illinois ... More >> Clinical Addictions Research Laboratory Recruiting Chicago, Illinois, United States, 60637 Contact: Patrick McNamara    773-702-5047    pmcnamar@bsdad.uchicago.edu    Principal Investigator: Andrea C King, PhD Less <<
NCT01092702 - Completed - -
NCT01624428 Tobacco Use Disorders Phase 1 Completed - United States, Connecticut ... More >> Substance Abuse Center New Haven, Connecticut, United States, 06519 Less <<
NCT03035708 Alcohol Use Disorder Phase 1 Phase 2 Completed - United States, Connecticut ... More >> Yale University School of Medicine New Haven, Connecticut, United States, 06511 United States, Rhode Island Brown University Providence, Rhode Island, United States, 02912 Less <<
NCT00548470 - Completed - -
NCT01061710 - Completed - -
NCT01092702 Tobacco Abstinence Phase 2 Phase 3 Completed - United States, Minnesota ... More >> Mayo Clinic Nicotine Research Program Rochester, Minnesota, United States, 55905 Less <<
NCT02892110 Substance Use Disorder Phase 2 Recruiting June 13, 2019 United States, South Carolina ... More >> Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29425 Less <<
NCT01061710 - Completed - -
NCT00733967 Methamphetamine Dependence ... More >> Substance Abuse Methamphetamine Abuse Less << Phase 1 Withdrawn(No longer active) - -
NCT00948155 - Completed - -
NCT03722966 Smoking Cessation Phase 2 Not yet recruiting August 30, 2020 -
NCT01694732 Chronic Obstructive Pulmonary ... More >>Disease COPD Exacerbation Smoking Less << Phase 3 Completed - France ... More >> CHU Angers Angers, France, 49933 Hôpital HIA Clermont Tonnerre Brest, France, 29200 Cavale Blanche Hospital Brest, France, 29609 CHRU Lille Lille, France, 59037 Laennec Hospital Nantes, France, 44093 Caremeau Hospital Nimes, France, 30029 Hotel Dieu Hospital Paris, France, 75004 HEGP Hospital Paris, France, 75015 Poitiers Hospital Poitiers, France, 86021 Cornouaille Hospital Quimper, France, 29107 Pontchaillou Rennes, France, 35033 Saint Brieuc Hospital Saint Brieuc, France, 22027 Bretonneau Hospital Tours, France, 37044 Less <<
NCT00661765 Smoking Cessation Phase 1 Completed - United States, North Dakota ... More >> Pfizer Investigational Site Fargo, North Dakota, United States, 58104 Less <<
NCT00602927 Nicotine Dependence Not Applicable Completed - United States, Pennsylvania ... More >> Tobacco Use Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT00948155 Nicotine Dependence Phase 4 Completed - United States, Pennsylvania ... More >> Tobacco Use Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT03262662 Tobacco Smoking Phase 3 Recruiting August 2021 United States, New York ... More >> University at Buffalo (SUNYBuffalo) Recruiting Buffalo, New York, United States, 14260 Contact: Larry W Hawk, PhD Less <<
NCT01341080 Parkinson Disease Phase 2 Recruiting December 2018 United States, Illinois ... More >> Rush University Medical Center Recruiting Chicago, Illinois, United States, 60612 Principal Investigator: Deborah A Hall, MD, PhD Less <<
NCT01436474 Chronic Pain ... More >>Opioid Dependence Less << Phase 1 Completed - United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less <<
NCT01347112 Smoking Tobac... More >>co Dependence Alcohol Dependence Less << Phase 2 Phase 3 Completed - United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 United States, Wisconsin Franciscan Skemp Hospital La Crosse, Wisconsin, United States, 54601 Less <<
NCT01347112 - Completed - -
NCT01365819 Methamphetamine Dependence ... More >> Substance Abuse Methamphetamine Abuse Less << Phase 2 Completed - United States, California ... More >> UCLA Vine Street Clinic Los Angeles, California, United States, 90036 Less <<
NCT00602927 - Completed - -
NCT01010204 Smoking Cessation ... More >> Bipolar Disorder Less << Phase 4 Completed - United States, Pennsylvania ... More >> Dubois Regional Medical Center DuBois, Pennsylvania, United States, 15801 Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT01365819 - Completed - -
NCT03365362 Tobacco Use Disorder ... More >> Opioid-use Disorder Less << Phase 4 Not yet recruiting January 2022 United States, New York ... More >> Albert Einstein College of Medicine of Yeshiva University Bronx, New York, United States, 10467 Less <<
NCT01850953 Craving Smoki... More >>ng Schizophrenia Less << Phase 4 Completed - Canada, Ontario ... More >> Centre for Addiction and Mental Health Toronto, Ontario, Canada, M5S 2S1 Less <<
NCT01378858 Tobacco Use Disorder ... More >> Medication Adherence Less << Not Applicable Completed - United States, New York ... More >> Albert Einstein College of Medicine Bronx, New York, United States, 10467 Less <<
NCT01228175 Smoking Addiction Phase 4 Completed - United States, New Mexico ... More >> The Mind Research Network Albuquerque, New Mexico, United States, 87106 Less <<
NCT01934023 Schizophrenia Phase 2 Completed - Canada, Ontario ... More >> Centre for Addiction and Mental Health Toronto, Ontario, Canada, M5T 1R8 Less <<
NCT01010204 - Completed - -
NCT01228175 - Completed - -
NCT02473562 Parkinson's Disease Phase 4 Terminated(insufficient patien... More >>t enrollment, insufficient funds for completion) Less << - Netherlands ... More >> Academic Medical Center Amsterdam, Netherlands, 1100 DD VU university medical center Amsterdam, Netherlands Less <<
NCT02894957 Smoking Cessation Phase 4 Not yet recruiting December 2019 -
NCT00895557 Varenicline and the Blunting o... More >>f Cocaine Cues Less << Phase 2 Withdrawn(This study never sta... More >>rted, no funding.) Less << December 2013 United States, Pennsylvania ... More >> University of Pennsylvania Treatment Research Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT02193256 Cigarette Smoking ... More >> Alcohol Use Disorders Less << Early Phase 1 Completed - United States, Connecticut ... More >> Yale University School of Medicine New Haven, Connecticut, United States, 06511 Less <<
NCT01639560 - Completed - -
NCT00813800 Smoking Bipol... More >>ar Disorder Depression Less << Not Applicable Completed - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT00813800 - Completed - -
NCT01639560 Smoking Phase 4 Completed - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT01632189 Nicotine Dependence Not Applicable Completed - Canada, Ontario ... More >> Centre for Addiction and Mental Health Toronto, Ontario, Canada Less <<
NCT00860028 - Completed - -
NCT03495024 Schizophrenia ... More >> Schizoaffective Disorder Tobacco Smoking Tardive Dyskinesia Parkinsonism Less << Phase 4 Not yet recruiting March 2019 -
NCT01571167 Methamphetamine Dependence ... More >> Methamphetamine Abuse Substance Abuse Less << Phase 1 Completed - United States, Texas ... More >> Michael E. DeBakey Veterans Affairs Medical Center Houston, Texas, United States, 77030 Less <<
NCT03742154 Smoking Smoki... More >>ng Cessation Smoking, Tobacco Smoking, Cigarette Less << Early Phase 1 Recruiting June 2020 United States, South Carolina ... More >> Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29425 Contact: Lisa Coles Less <<
NCT00860028 Nicotine Dependence ... More >> Smoking Heavy Drinking Less << Phase 2 Completed - -
NCT03059563 Dopamine D2/3 Receptor Availab... More >>ility Cognitive Function Methamphetamine Abuse Less << Phase 1 Enrolling by invitation October 2019 United States, California ... More >> University of California Los Angeles Los Angeles, California, United States, 90024 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.73mL

0.95mL

0.47mL

23.67mL

4.73mL

2.37mL

47.34mL

9.47mL

4.73mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

Categories