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Chemical Structure| 847559-80-2 Chemical Structure| 847559-80-2

Structure of VER-82576
CAS No.: 847559-80-2

Chemical Structure| 847559-80-2

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NVP-BEP800 is a fully synthetic HSP90β inhibitor with IC50 of 58 nM, exhibits> 70-fold selectivity against Hsp90 family members Grp94 and Trap-1.

Synonyms: NVP-BEP800

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Product Details of VER-82576

CAS No. :847559-80-2
Formula : C21H23Cl2N5O2S
M.W : 480.41
SMILES Code : O=C(C1=CC2=C(C3=CC(OCCN4CCCC4)=C(Cl)C=C3Cl)N=C(N)N=C2S1)NCC
Synonyms :
NVP-BEP800
MDL No. :MFCD18251568
InChI Key :WJUNQSYQHHIVFX-UHFFFAOYSA-N
Pubchem ID :25210273

Safety of VER-82576

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317-H319
Precautionary Statements:P280-P305+P351+P338

Related Pathways of VER-82576

DNA

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
ST cells 250, 500, 1000 nM 24 hours To evaluate the inhibitory effect of VER-82576 on TGEV infection. The results showed that VER-82576 significantly inhibited TGEV infection in a dose-dependent manner. PMC10649137
LLC-PK cells 250, 500, 1000 nM 24 hours To evaluate the inhibitory effect of VER-82576 on PDCoV infection, results showed that VER-82576 significantly suppressed PDCoV infection. PMC10789647

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.08mL

0.42mL

0.21mL

10.41mL

2.08mL

1.04mL

20.82mL

4.16mL

2.08mL

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