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Chemical Structure| 599179-03-0 Chemical Structure| 599179-03-0

Structure of Vicriviroc maleate
CAS No.: 599179-03-0

Chemical Structure| 599179-03-0

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Vicriviroc maleate is a CCR5 antagonist with IC50 of 0.91 nM in clinical development for the treatment of HIV-1.

Synonyms: SCH-D maleate; SCH-417690 maleate; SCH 417690

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Product Details of Vicriviroc maleate

CAS No. :599179-03-0
Formula : C32H42F3N5O6
M.W : 649.70
SMILES Code : CC1(N2C[C@H](C)N([C@H](C3=CC=C(C(F)(F)F)C=C3)COC)CC2)CCN(C(C4=C(C)N=CN=C4C)=O)CC1.O=C(O)/C=C\C(O)=O
Synonyms :
SCH-D maleate; SCH-417690 maleate; SCH 417690
MDL No. :MFCD09833218

Safety of Vicriviroc maleate

Related Pathways of Vicriviroc maleate

GPCR

Isoform Comparison

Biological Activity

Target
  • HIV Protease

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00551330 HIV Infections ... More >> Acquired Immunodeficiency Syndrome Less << Phase 2 Completed - -
NCT00705419 - Completed - -
NCT00243230 HIV Infections Phase 2 Completed - -
NCT00686829 HIV Infections Phase 2 Completed - -
NCT00632073 HIV Infections Phase 1 Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.54mL

0.31mL

0.15mL

7.70mL

1.54mL

0.77mL

15.39mL

3.08mL

1.54mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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