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Chemical Structure| 327031-55-0 Chemical Structure| 327031-55-0

Structure of VLX600
CAS No.: 327031-55-0

Chemical Structure| 327031-55-0

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VLX600 is a novel iron-chelating inhibitor of oxidative phosphorylation, potentiated the effect of radiation in tumor spheroids in a synergistic manner. VLX600 is preferentially active against quiescent cells in colon cancer 3-D microtissues. VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvation and displays tumour growth inhibition in vivo.

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Product Details of VLX600

CAS No. :327031-55-0
Formula : C17H15N7
M.W : 317.35
SMILES Code : C/C(C1=NC=CC=C1)=N\NC2=NN=C3C(NC4=C3C=CC=C4C)=N2
MDL No. :MFCD01305422
InChI Key :UQOSBPRTQFFUOA-SRZZPIQSSA-N
Pubchem ID :6410104

Safety of VLX600

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02222363 Refractory Cancer PHASE1 TERMINATED 2016-12-28 Mayo Clinic Scottsdale, Scotts... More >>dale, Arizona, 85259-5499, United States|Mayo Clinic Jacksonville, Jacksonville, Florida, 32224, United States|Mayo Clinic Rochester, Rochester, Minnesota, 55905, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.15mL

0.63mL

0.32mL

15.76mL

3.15mL

1.58mL

31.51mL

6.30mL

3.15mL

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