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Chemical Structure| 1523404-29-6 Chemical Structure| 1523404-29-6

Structure of Vps34-IN-2
CAS No.: 1523404-29-6

Chemical Structure| 1523404-29-6

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Vps34-IN-2 is a novel and effective Vps34 inhibitor with IC50 values of 2 nM and 82 nM in enzyme and cell assays, respectively. This compound exhibits antiviral activity against SARS-CoV-2, HCoV-229E, and HCoV-OC43, making it suitable for research on viral infections.

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Product Details of Vps34-IN-2

CAS No. :1523404-29-6
Formula : C18H25F3N4O3
M.W : 402.41
SMILES Code : O=C1C=C(N2[C@H](C)COCC2)N=C3N(CC(C(C)C)=O)[C@H](C(F)(F)F)CCN31
MDL No. :MFCD28411355
InChI Key :ITCIAOUZMPREOO-OCCSQVGLSA-N
Pubchem ID :72709284

Safety of Vps34-IN-2

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Vps34-IN-2

PI3K-AKT

Isoform Comparison

Biological Activity

Description
Vps34-IN-2 is a newly discovered, potent, and selective inhibitor of Vps34, with IC50 values of 2 and 82 nM in the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively [1].

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