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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 155584-74-0 Chemical Structure| 155584-74-0

Structure of VUF10166
CAS No.: 155584-74-0

Chemical Structure| 155584-74-0

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VUF10166 is a potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of VUF10166

CAS No. :155584-74-0
Formula : C13H15ClN4
M.W : 262.74
SMILES Code : CN1CCN(C2=NC3=CC=CC=C3N=C2Cl)CC1
MDL No. :MFCD01127814
InChI Key :FFXVTQDGTKEXHF-UHFFFAOYSA-N
Pubchem ID :24278976

Safety of VUF10166

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of VUF10166

GPCR

Isoform Comparison

Biological Activity

Target
  • 5-HT3

    5-HT3A, Ki:0.04 nM

    5-HT3AB, Ki:22 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.81mL

0.76mL

0.38mL

19.03mL

3.81mL

1.90mL

38.06mL

7.61mL

3.81mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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