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Chemical Structure| 1824637-41-3 Chemical Structure| 1824637-41-3

Structure of VY-3-135
CAS No.: 1824637-41-3

Chemical Structure| 1824637-41-3

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VY-3-135 is a orally active stable ACSS2 inhibitor with an IC50 of 44 nM. VY-3-135 specifically targets ACSS2 in the AcCoA synthetase family. It does not inhibit ACSS1 or ACSS3 enzyme activity. VY-3-135 can be used in breast cancer research.

Synonyms: VY-3-135

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Product Details of VY-3-135

CAS No. :1824637-41-3
Formula : C26H27N3O3
M.W : 429.51
SMILES Code : O=C(C1=CC=C2N=C(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)N(CC)C2=C1)NC[C@H](O)C
Synonyms :
VY-3-135
MDL No. :N/A
InChI Key :KTPYOTKTDCLZHR-GOSISDBHSA-N
Pubchem ID :92131155

Safety of VY-3-135

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.33mL

0.47mL

0.23mL

11.64mL

2.33mL

1.16mL

23.28mL

4.66mL

2.33mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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