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Chemical Structure| 315703-81-2 Chemical Structure| 315703-81-2

Structure of WAY-118959-A
CAS No.: 315703-81-2

Chemical Structure| 315703-81-2

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WAY-118959-A is a tubulin acetylation inhibitor that directly binds α-tubulin and prevents α-tubulin acetyltransferase 1 (αTAT1) from acting on the K40 residue of α-tubulin. GM-90257 induces apoptosis in MDA-MB-231 cells while having minimal effects on MCF-10A or MCF-7 cells with lower levels of tubulin acetylation.

Synonyms: GM-90257

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Product Details of WAY-118959-A

CAS No. :315703-81-2
Formula : C16H14N4OS2
M.W : 342.44
SMILES Code : CC1=C(C2=CSC(NC3=CC=C(OC)C=C3)=N2)N4C(SC=C4)=N1
Synonyms :
GM-90257

Safety of WAY-118959-A

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of WAY-118959-A

cytoskeleton

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.92mL

0.58mL

0.29mL

14.60mL

2.92mL

1.46mL

29.20mL

5.84mL

2.92mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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