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Chemical Structure| 1338574-93-8 Chemical Structure| 1338574-93-8

Structure of WWL154
CAS No.: 1338574-93-8

Chemical Structure| 1338574-93-8

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WWL154 is a selective monoacylglycerol lipase (MAGL) inhibitor that increases levels of 2-arachidonoylglycerol (2-AG) by inhibiting MAGL, thereby activating cannabinoid receptors (CB1 and CB2) and regulating neuronal activity and immune response.

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Product Details of WWL154

CAS No. :1338574-93-8
Formula : C18H19N3O5
M.W : 357.36
SMILES Code : O=C(N1CCN(C2=CC=C(OC)C=C2)CC1)OC3=CC=C([N+]([O-])=O)C=C3
MDL No. :MFCD32066932
InChI Key :TULVXRNEEQWFGU-UHFFFAOYSA-N
Pubchem ID :46829229

Safety of WWL154

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Description
WWL154, a JZL184 analog retaining the SH-reactive p-nitrophenyl carbamate group, serves as a FAAH-4 inhibitor [1].

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1 mM

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2.80mL

0.56mL

0.28mL

13.99mL

2.80mL

1.40mL

27.98mL

5.60mL

2.80mL

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