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Chemical Structure| 122955-42-4 Chemical Structure| 122955-42-4

Structure of XE991
CAS No.: 122955-42-4

Chemical Structure| 122955-42-4

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XE991 is a potent and selective blocker of KV7 (KCNQ) voltage-gated potassium channels which blocks KV7.2+7.3 (KCNQ2+3) / M-currents (IC50 = 0.6 - 0.98 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 0.75 μM) but is less potent against KV7.1/minK channels (IC50 = 11.1 μM).

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Product Details of XE991

CAS No. :122955-42-4
Formula : C26H20N2O
M.W : 376.45
SMILES Code : O=C1C2=C(C=CC=C2)C(CC3=CC=NC=C3)(CC4=CC=NC=C4)C5=CC=CC=C15
MDL No. :MFCD09055426

Safety of XE991

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.66mL

0.53mL

0.27mL

13.28mL

2.66mL

1.33mL

26.56mL

5.31mL

2.66mL

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