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Chemical Structure| 288250-47-5 Chemical Structure| 288250-47-5

Structure of Y-320
CAS No.: 288250-47-5

Chemical Structure| 288250-47-5

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Y-320 is a phenylpyrazoleanilide immuno modulator and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.

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Product Details of Y-320

CAS No. :288250-47-5
Formula : C27H29ClN6O2
M.W : 505.01
SMILES Code : O=C(C1=C(C)N(C2=CC=C(Cl)C=C2)N=C1)NC3=CC=C(N4CCC(N5CCOCC5)CC4)C(C#N)=C3
MDL No. :MFCD28099803
InChI Key :BWZNJVZTAWBIFG-UHFFFAOYSA-N
Pubchem ID :22227931

Safety of Y-320

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Related Pathways of Y-320

pyroptosis

Isoform Comparison

Biological Activity

Description
Y-320, a potent phenylpyrazoleanilide immunomodulator, is recognized for its oral activity. It suppresses IL-17 production by CD4 T cells stimulated with IL-15, presenting IC50 values ranging from 20 to 60 nM. This compound also bolsters TP53, DMD, and COL17A1 PTC readthrough alongside G418, elevating both cellular protein levels and protein synthesis. When used with a low dosage of Paclitaxel, Y-320 notably increases the sensitivity of multidrug resistance (MDR) tumors to the drug, triggering G2/M phase arrest and apoptosis. Y-320's applications extend to rheumatoid arthritis (RA) and cancer research[1].[2].

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.98mL

0.40mL

0.20mL

9.90mL

1.98mL

0.99mL

19.80mL

3.96mL

1.98mL

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