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Chemical Structure| 2417408-46-7 Chemical Structure| 2417408-46-7

Structure of YX-2-107
CAS No.: 2417408-46-7

Chemical Structure| 2417408-46-7

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YX-2-107 is a PROTAC targeting the degradation of CDK6, with an IC50 value of 4.4 nM, effectively inhibiting intracellular RB phosphorylation and FOXM1 expression, showing potential for inhibiting Ph+ ALL, suitable for acute lymphoblastic leukemia research.

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Product Details of YX-2-107

CAS No. :2417408-46-7
Formula : C45H51N11O9
M.W : 889.95
SMILES Code : O=C(NCCCCNCC(N1CCN(C2=CC=C(NC3=NC=C(C(C)=C(C(C)=O)C(N4C5CCCC5)=O)C4=N3)N=C2)CC1)=O)COC6=CC=CC(C(N7C(CC8)C(NC8=O)=O)=O)=C6C7=O

Safety of YX-2-107

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of YX-2-107

Hedgehog

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.12mL

0.22mL

0.11mL

5.62mL

1.12mL

0.56mL

11.24mL

2.25mL

1.12mL

 

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