Structure of Zasocitinib
CAS No.: 2272904-53-5
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Zasocitinib is a highly selective Tyk2 inhibitor targeting the JH2 domain of Tyk2, exhibiting potent anti-inflammatory and antitumor activities, suitable for immunology and cancer research.
Synonyms: Ndi-034858; TAK-279
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 2272904-53-5 |
Formula : | C23H24N8O3 |
M.W : | 460.49 |
SMILES Code : | O=C(C1=C2N=C(NC3=CC=CN(C4=NC=CC=C4)C3=O)C=C(NC)N2N=C1)N[C@H]5[C@H](OC)CC5 |
Synonyms : |
Ndi-034858; TAK-279
|
MDL No. : | N/A |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319 |
Precautionary Statements: | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Description |
Zasocitinib (NDI-034858) is an inhibitor of TYK2, targeting the TYK2 JH2 domain with a binding constant Kd of <200 pM[1].
|
Clinical Trial:
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NCT06323356 | Generalized Pustular Psoriasis... More >>|Erythrodermic Psoriasis Less << | PHASE3 | RECRUITING | 2026-03-27 | Nagoya City University Hospita... More >>l, Nagoya, Aichi, Japan|Fujita Health University Hospital, Toyoake, Aichi, Japan|Kimitsu Chuo Hospital, Kisarazu, Chiba, Japan|Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan|Hospital of the University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan|Isesaki Municipal Hospital, Isesaki, Gunma, Japan|Kobe University Hospital, Kobe, Hyogo, Japan|Tokai University Hospital, Isehara, Kanagawa, Japan|Mie University Hospital, Tsu, Mie, Japan|Kansai Medical University Hospital, Hirakata, Osaka, Japan|Saitama Medical University Hospital, Iruma, Saitama, Japan|St.Luke's International Hospital, Chuo City, Tokyo, Japan|Teikyo University Hospital, Itabashi-ku, Tokyo, Japan|The Jikei University Hospital, Minato-ku, Tokyo, Japan|Tokyo Medical University Hospital, Shinjuku-ku, Tokyo, Japan|Fukuoka University Hospital, Fukuoka, Japan|University Hospital, Kyoto Prefectural University of Medicine, Kyoto, Japan|Okayama University Hospital, Okayama, Japan|Nippon Life Hospital, Osaka, Japan|Osaka Metropolitan University Hospital, Osaka, Japan Less << |
NCT05976321 | Hepatic Impairment|Healthy Vol... More >>unteers Less << | PHASE1 | COMPLETED | 2024-04-15 | University of Miami, Miami, Fl... More >>orida, 33146, United States|Orlando Clinical Research Center, Orlando, Florida, 32809, United States|American Research Corporation - Texas Liver Institute, San Antonio, Texas, 78215, United States|Pinnacle Clinical Research - San Antonio, San Antonio, Texas, 78229, United States Less << |
NCT05992155 | Renal Impairment|Healthy Volun... More >>teers Less << | PHASE1 | COMPLETED | 2024-05-28 | Clinical Pharmacology of Miami... More >>, Miami, Florida, 33014, United States|Orlando Clinical Research Center, Orlando, Florida, 32809, United States|Research by Design, Chicago, Illinois, 60643, United States Less << |
NCT06550076 | Plaque Psoriasis | PHASE3 | RECRUITING | 2026-05-07 | Total Dermatology, Birmingham,... More >> Alabama, 35205, United States|University of Alabama Hospital - Whitaker Clinic -, Birmingham, Alabama, 35233-2110, United States|Cahaba Dermatology Skin Health Center, Hoover, Alabama, 35244-2111, United States|Medical Dermatology Specialists, Phoenix, Arizona, 85006, United States|Saguaro Dermatology Associates, LLC - Probity - PPDS, Phoenix, Arizona, 85008-3884, United States|Noble Clinical Research, Tucson, Arizona, 85704, United States|Johnson Dermatology Clinic, Fort Smith, Arkansas, 72916-6103, United States|Burke Pharmaceutical Research, Hot Springs, Arkansas, 71913-6475, United States|Zenith Research, Inc., Beverly Hills, California, 90212, United States|First OC Dermatology Research Inc., Fountain Valley, California, 92708, United States|Center for Dermatology Clinical Research, Fremont, California, 94538, United States|Long Beach Research Institute, Long Beach, California, 90805, United States|Metropolis Dermatology Downtown LA - Probity - PPDS, Los Angeles, California, 90017-5310, United States|UCLA University of California Los Angeles, Los Angeles, California, 90024, United States|Northridge Clinical Trials, Northridge, California, 91325-4122, United States|UC Davis Dermatology Clinic, Sacramento, California, 95816-3370, United States|TCR Medical Corporation, San Diego, California, 92123-1523, United States|University Clinical Trials, San Diego, California, 92123, United States|Dermatology Institute and Skin Care Center, Santa Monica, California, 90404-2216, United States|UNISON Clinical Trials (Shahram Jacobs md inc.), Sherman Oaks, California, 91403, United States|Driven Research LLC, Coral Gables, Florida, 33134-3901, United States|Revival Research Corporation - Florida - ClinEdge - PPDS, Doral, Florida, 33122-1902, United States|FXM Clinical Research Ft. Lauderdale, LLC, Fort Lauderdale, Florida, 33308-5211, United States|Direct Helpers Medical Center, Hialeah, Florida, 33012, United States|San Marcus Research Clinic Inc, Miami Lakes, Florida, 33014, United States|Florida Academic Centers Research, Miami, Florida, 33136-1003, United States|FXM Clinical Research Miami, LLC, Miami, Florida, 33175-3582, United States|FXM Research Miramar, Miramar, Florida, 33027-4714, United States|Renstar Medical Research -21 NE 1st Ave, Ocala, Florida, 34470, United States|Lenus Research & Medical Group, Sweetwater, Florida, 33172, United States|Advanced Clinical Research Institute (ACRI) - Florida, Tampa, Florida, 33607-6429, United States|Divine Dermatology and Aesthetics, LLC, Atlanta, Georgia, 30315-2042, United States|Marietta Dermatology & The Skin Cancer Center - Marietta, Marietta, Georgia, 30060-7902, United States|Advanced Medical Research, PC, Sandy Springs, Georgia, 30328, United States|Georgia Skin and Cancer Clinic, Savannah, Georgia, 31419-1768, United States|Leavitt Clinical Research, Idaho Falls, Idaho, 83404-8322, United States|Arlington Dermatology, Rolling Meadows, Illinois, 60008-3811, United States|NorthShore Medical Group Dermatology - Skokie, Skokie, Illinois, 60077-1049, United States|DS Research - 1005 E. Lewis & Clark Pkwy Indiana Location, Clarksville, Indiana, 47129-2201, United States|Dawes Fretzin Clinical Research Group, LLC, Indianapolis, Indiana, 46250, United States|Skin Sciences, PLLC, Louisville, Kentucky, 40217-1444, United States|Dermatology Specialists Research - 3810 Springhurst Blvd, Louisville, Kentucky, 40241-6162, United States|Lawrence J Green, MD LLC, Rockville, Maryland, 20850, United States|University of Michigan Hospital - 1500 E Medical Center Dr, Ann Arbor, Michigan, 48109-5360, United States|Oakland Hills Dermatology - 3400 Auburn Rd, Auburn Hills, Michigan, 48326-3396, United States|Revival Research Corporation - ClinEdge, Troy, Michigan, 48084-3536, United States|Minnesota Clinical Study Center, New Brighton, Minnesota, 55112, United States|Skin Specialists PC, Omaha, Nebraska, 68144, United States|Henderson Clinical Trials, Henderson, Nevada, 89052, United States|Dartmouth Hitchcock Medical Center - Old Etna Rd, Lebanon, New Hampshire, 03766-1937, United States|ALLCUTIS Research, LLC., Portsmouth, New Hampshire, 03801, United States|Psoriasis Treatment Center of Central New Jersey, East Windsor, New Jersey, 08520, United States|Montefiore AOA - BRANY, Bronx, New York, 10467, United States|Sadick Research Group, New York, New York, 10075-0385, United States|Accellacare of Cary, Cary, North Carolina, 27518, United States|The Skin Surgery Center for Clinical Research - Objective Health - PPDS, Winston-Salem, North Carolina, 27103-7109, United States|Bexley Dermatology Research - Probity - PPDS, Bexley, Ohio, 43209, United States|Wright State Physicians, Fairborn, Ohio, 45324, United States|Apex Clinical Research Center, Mayfield Heights, Ohio, 44124-4005, United States|Oregon Medical Research Center PC, Portland, Oregon, 97201, United States|University of Pittsburgh Medical Center-3601 5th Ave, Pittsburgh, Pennsylvania, 15213-3403, United States|Cumberland Skin Center for Clinical Research - Objective Health - PPDS, Hermitage, Tennessee, 37076-3497, United States|International Clinical Research US LLC, Murfreesboro, Tennessee, 37130-2450, United States|Arlington Research Center, Arlington, Texas, 76011-3800, United States|Bellaire Dermatology Associates, Bellaire, Texas, 77401-3505, United States|UT Physicians Dermatology - Bellaire Station, Bellaire, Texas, 77401, United States|Modern Research Associates, Dallas, Texas, 75231-6077, United States|North Texas Center for Clinical Research, Frisco, Texas, 75034, United States|San Antonio, San Antonio, Texas, 78213-2250, United States|Texas Dermatology and Laser Specialists-San Antonio-7703 Floyd Curl Dr, San Antonio, Texas, 78218-3128, United States|Dermatology Clinical Research Center of San Antonio, San Antonio, Texas, 78229-3409, United States|Houston Center for Clinical Research, LLC, Sugar Land, Texas, 77479-1001, United States|Center For Clinical Studies, LTD. LLP - 451 N Texas Ave, Webster, Texas, 77598-4927, United States|Virginia Clinical Research - 6160 Kempsville Cir, Norfolk, Virginia, 23507, United States|Conexa Investigación Clínica S.A., Ciudad Autónoma de Buenos Aires, Ciudad Autónoma De BuenosAires, C1012, Argentina|Centro de Investigaciones Médicas Tucumán, San Miguel de Tucuman, Tucumán, T4000, Argentina|Instituto de Dermatología y Neumonología, Buenos Aires, Argentina|Centro de Investigacion Clinica, Ciudad Autónomade Buenos Aires, C1060ABN, Argentina|St George Dermatology and Skin Cancer Center - Probity - Probity, Kogarah, New South Wales, 2217, Australia|The Skin Center - Probity, Benowa, Queensland, 4217, Australia|Skin Health Institute Inc - Probity - PPDS, Carlton, Victoria, 3053, Australia|Sinclair Dermatology-East Melbourne, East Melbourne, Victoria, 3002, Australia|Alfred Health, Parkville, Victoria, 3050, Australia|Western Health - Sunshine Hospital, Parkville, Victoria, 3050, Australia|Medical Center Unimed EOOD-Sevlievo, Sevlievo, Gabrovo, 5400, Bulgaria|Medical Center Asklepii OOD, Dupnitsa, Kjustendil, 2600, Bulgaria|Diagnostic and Consulting Center Aleksandrovska EOOD, Sofia, Sofia-Grad, 1431, Bulgaria|Diagnostic Consultative Centre - Focus-5 - LZIP EOOD, Sofia, Sofia-Grad, 1463, Bulgaria|Medical Center Hera EOOD-Sofia, Sofia, Sofia-Grad, 1510, Bulgaria|Diagnostic Consultative Center XXVIII - Sofia - EOOD, Sofia, Sofia-Grad, 1592, Bulgaria|Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia, Sofia, Sofia-Grad, 1606, Bulgaria|MC Comac Medical, Sofia, Sofia-Grad, 1612, Bulgaria|Multiprofile Hospital For Active Treatment Dr Tota Venkova, Gabrovo, Bulgaria|Diagnostic Consultative Center Sveti, Haskovo, 6300, Bulgaria|Medical Center Medconsult Pleven OOD, Pleven, Bulgaria|Beacon Dermatology - Probity, Calgary, Alberta, T3A 2N1, Canada|Dermatology Research Institute, Inc., Calgary, Alberta, T3A 2N1, Canada|Alberta DermaSurgery Centre - Probity, Edmonton, Alberta, T6G 1C2, Canada|VIDA Dermatology - Probity, Edmonton, Alberta, T6H 4J8, Canada|Care Clinic, Red Deer, Alberta, T4P 1K4, Canada|Enverus Medical Research - Probity, Surrey, British Columbia, V3V 0C6, Canada|Wiseman Dermatology Research Inc., Winnipeg, Manitoba, R3E 0V9, Canada|Karma Clinical Trials, St. John's, Newfoundland and Labrador, A1A 4Y3, Canada|CCA Medical Research - Probity, Ajax, Ontario, L1S 7K8, Canada|SimcoDerm Medical and Surgical Dermatology Centre - Probity, Barrie, Ontario, L4M 7G1, Canada|Kingsway Clinical Research - Probity, Etobicoke, Ontario, M8X 1Y9, Canada|Guelph Dermatology Research - Probity, Guelph, Ontario, N1L 0B7, Canada|Lima's Excellence In Allergy And Dermatology Research (Leader) Inc. - Probity, Hamilton, Ontario, L8L 3C3, Canada|Dermatrials Research, Hamilton, Ontario, L8N 1Y2, Canada|Mediprobe Research Inc, London, Ontario, N5X 2P1, Canada|DermEffects, London, Ontario, N6H 5L5, Canada|Lynderm Research Inc - Probity, Markham, Ontario, L3P 1X3, Canada|DermEdge Research - Probity, Mississauga, Ontario, L5H 1G9, Canada|Dr. S. K. Siddha Medicine Professional Corporation | Newmarket, Canada, Newmarket, Ontario, Canada|North Bay Dermatology Center - Probity, North Bay, Ontario, P1B 3Z7, Canada|The Centre for Clinical Trials Inc., Oakville, Ontario, L6J 7W5, Canada|Skin Centre for Dermatology, Peterborough, Ontario, K9J 5K2, Canada|The Centre For Dermatology, Richmond Hill, Ontario, L4B 1A5, Canada|North York Research Inc. - Probity, Toronto, Ontario, M2N 3A6, Canada|Canadian Dermatology Centre - Probity, Toronto, Ontario, M3B 0A7, Canada|Toronto Research Centre, Toronto, Ontario, M3H 5Y8, Canada|Toronto Research Centre - Probity, Toronto, Ontario, M4W 2N4, Canada|Alliance Clinical Trials, Waterloo, Ontario, N2J 1C4, Canada|XLR8 Medical Research, Windsor, Ontario, N8T 1E6, Canada|Siena Medical Research Corporation, Montreal, Quebec, H3Z 2S6, Canada|Skinsense Medical Research - Probity, Saskatoon, Saskatchewan, S7K 0H6, Canada|Peking University People's Hospital, Beijing, Beijing, 100044, China|Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing, 100050, China|Peking University Third Hospital, Beijing, Beijing, 100191, China|Beijing Tongren Hospital, Capital Medical University, Beijing, Beijing, 100730, China|The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, 400016, China|The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China|Guangdong Provincial People's Hospital, Guangzhou, Guangdong, 510080, China|Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong, 510091, China|Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510120, China|Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, 510280, China|The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050031, China|Union Hospital Tongji Medical College of Huazhong University of Science and Technology (HUST), Wuhan, Hubei, 430022, China|Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, 430030, China|Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China|Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, China|Huashan Hospital Fudan University - PPDS, Shanghai, Minhang District, 201100, China|General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China|Shandong Provincial Hospital, Jinan, Shandong, 250013, China|Shanghai Skin Disease Hospital, Shanghai, Shanghai, 200020, China|First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, China|The 2nd Hospital of Xi'An Jiaotong University, Xi'an, Shanxi, 710004, China|West China Hospital Sichuan University, Chengdu, Sichuan, 610041, China|Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310000, China|Sir Run Run Shaw Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310016, China|The 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China|The University of Hong Kong - Shenzhen Hospital, Shenzhen, China|Pratia Brno s.r.o. - PRATIA - PPDS, Brno, Jihomoravsky Kraj, 602 00, Czechia|Dermamedica, s.r.o. - Kozni Ambulance Nachod, Nachod, Královéhradecky Kraj, 547 01, Czechia|Nemocnice AGEL Novy Jicin a.s, Novy Ji?ín, Moravskoslezsky Kraj, Czechia|CCR Ostrava s.r.o., Ostrava, Moravskoslezsky Kraj, 702 00, Czechia|Dermskin s.r.o, Olomouc, Olomoucky Kraj, 779 00, Czechia|Pratia Pardubice a.s. - PRATIA - PPDS, Pardubice, Pardubicky Kraj, 530 02, Czechia|Praglandia, Prague, 150 00, Czechia|CLINTRIAL s.r.o., Praha 10, 100 00, Czechia|Fakultni nemocnice Kralovske Vinohrady, Praha 10, 779 00, Czechia|Prof. MUDr. Petr Arenberger, DrSc. - CRC - PPDS, Praha 1, 110 00, Czechia|Hautarztpraxis Mahlow, Blankenfelde-Mahlow, Brandenburg, 15831, Germany|Fachklinik Bad Bentheim, Bad Bentheim, Niedersachsen, 48455, Germany|Klinikum Oldenburg, Oldenburg, Niedersachsen, 26133, Germany|Klinische Forschung Dresden Gmbh, Dresden, Sachsen, 01069, Germany|Praxis fur Dermatologie and Venerologie, Dresden, Sachsen, 01097, Germany|SRH Wald-Klinikum Gera GmbH, Gera, Thüringen, 07548, Germany|Dermatologikum Hamburg, Hamburg, 20354, Germany|Allergo-Derm Bakos Kft., Szolnok, Jász-Nagykun-Szolnok, 5000, Hungary|Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Somogy, 7400, Hungary|Markusovszky Egyetemi Oktatókórház, Szombathely, Vas, Hungary|Debreceni Egyetem, Debrecen, 4032, Hungary|Rabin Medical Center - PPDS, Petach Tikva, Israel|Chaim Sheba Medical Center, Ramat Gan, 5265602, Israel|IRCCS Istituto Clinico Humanitas, Rozzano, Milano, 20089, Italy|Presidio Ospedaliero Gaspare Rodolico, Catania, Sicilia, 95123, Italy|Azienda Usl Toscana Centro - Firenze, Firenze, Toscana, 50125, Italy|Nagoya City University Hospital, Nagoya-City, Aichi, 467-8602, Japan|Takagi Dermatological Clinic, Obihiro-Shi, Hokkaid?, 080-0013, Japan|JR Sapporo Hospital, Sapporo-Shi, Hokkaid?, 060-0033, Japan|Medical Corporation Kojinkai Sapporo Skin Clinic, Sapporo-Shi, Hokkaid?, 060-0063, Japan|Fukuoka University Hospital, Fukuoka-Shi, Hukuoka, 814-0180, Japan|Saruwatari Dermatology Clinic, Kagoshima-Shi, Kagosima, 892-0826, Japan|Jichi Medical University Hospital, Shimotsuke-shi, Tochigi-Ken, 329-0498, Japan|JCHO Tokyo Yamate Medical Center, Shinjuku-ku, Tokyo-To, 169-0073, Japan|Tokyo Teishin Hospital, Sumida-Ku, Tokyo, Japan|Ohyama Dermatology Clinic, Kumamoto, 861-4101, Japan|Tokyo Medical University Hospital, Tokyo, 160-0023, Japan|Dermatology and Ophthalmology Kume Clinic, Sakai-Shi, ?saka, 593-8324, Japan|Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon-do, 220-701, Korea, Republic of|Chosun University Hospital, Gwangju, Gwangju Gwang'yeogsi, 61453, Korea, Republic of|Seoul National University Bundang Hospital, Beon-gil Bundang-gu, Gyeonggi-do, 13620, Korea, Republic of|The Catholic University of Korea, Bucheon St. Mary's Hospital, Bucheon-si, Gyeonggido, 14647, Korea, Republic of|Konkuk University Medical Center, Gwangjin-Gu, Seoul Teugbyeolsi, 05030, Korea, Republic of|The Catholic University of Korea, Seoul St. Mary's Hospital, Seocho-Gu, Seoul Teugbyeolsi, 06591, Korea, Republic of|Soon Chun Hyang University Hospital Seoul, Seoul, Seoul Teugbyeolsi, 04401, Korea, Republic of|Kyung Hee University Hospital, Seoul, 2447, Korea, Republic of|Seoul National University Hospital, Seoul, 3080, Korea, Republic of|Chung-Ang University Hospital, Seoul, Korea, Republic of|Smite Aija medical practice in dermatology, venerology, Talsi, Talsu Aprinkis, LV-3201, Latvia|Semigallia, Kuldīga, LV-3301, Latvia|Riga 1st Hospital, Riga, LV-1001, Latvia|Aesthetic dermatology clinic of prof. J. Kisis, Riga, LV-1003, Latvia|Health Center 4-1 Grebenscikova Str, Riga, LV-1003, Latvia|Veseliba un estetika Ltd., Riga, LV-1009, Latvia|Outpatient Clinic Adoria, Riga, LV-1011, Latvia|Health Center 4-Skanstes iela 50, Riga, LV-1013, Latvia|Centrum Medyczne Katowice - PRATIA, Katowice, Dolnoslaskie, 40-081, Poland|Globe Badania Kliniczne Spolka z o.o. - Klodzko, Klodzko, Dolnoslaskie, 57-300, Poland|Cityclinic Przychodnia lekarsko psychologiczna Matusiak sp.p, Wroclaw, Dolnoslaskie, 50-566, Poland|Velocity Skierniewice Sp. z o.o., Skierniewice, Lodzkie, 96-100, Poland|Dermoklinika-Centrum Medyczne s.c, ?ód?, Lodzkie, 90-436, Poland|Clinical Best Solutions Sp. z o.o. S.K., Lublin, Lubelskie, 20-011, Poland|Luxderm Specjalistyczny Gabinet Dermatologiczny Dorota Krasowska, Lublin, Lubelskie, 20-573, Poland|Centrum Terapii Wspó?czesnej J.M. Jasnorzewska S.K.A., Lódz, Lódzkie, 90-338, Poland|Centrum Medyczne ALL-MED, Krakow, Malopolskie, 30-033, Poland|Pratia MCM Krakow, Krakow, Malopolskie, 30-727, Poland|Krakowskie Centrum Medyczne Sp. z o.o., Kraków, Malopolskie, 31-501, Poland|Rheumatology Clinic NZOZ Lecznica MAK-MED, Nadarzyn, Mazowieckie, 05-830, Poland|ETG Siedlce - PPDS, Siedlce, Mazowieckie, 08-110, Poland|RCMed Oddzial Sochaczew, Sochaczew, Mazowieckie, 96-500, Poland|Klinika Reuma Park sp . zoo Sp.k., Warsaw, Mazowieckie, 02-691, Poland|Clinical Best Solutions Sp. z o.o. S.K., Warszawa, Mazowieckie, 00-710, Poland|MICS Centrum Medyczne Warszawa, Warszawa, Mazowieckie, 00-874, Poland|Clinical Research Group Sp. z o.o, Warszawa, Mazowieckie, 01-142, Poland|High-Med Przychodnia Specjalistyczna, Warszawa, Mazowieckie, 01-817, Poland|AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Warszawie, Warszawa, Mazowieckie, 02-672, Poland|ETG Warszawa - PPDS, Warszawa, Mazowieckie, 02-677, Poland|Klinika Ambroziak Dermatologia, Warszawa, Mazowieckie, 02-953, Poland|FutureMeds - Targowek - PPDS, Warszawa, Mazowieckie, 03-291, Poland|NZOZ Osteo Medic SC Artur Racewicz Jerzy Supronik, Bialystok, Podlaskie, 15-351, Poland|ClinicMed Daniluk, Nowak Spolka Komandytowa, Bialystok, Podlaskie, 15-879, Poland|Centrum Medyczne Chojnice - PRATIA - PPDS, Chojnice, Pomorskie, 89-600, Poland|AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Gdansku, Gdansk, Pomorskie, 80-382, Poland|Copernicus Podmiot Leczniczy Sp. z o.o, Szpital Sw. Wojciecha, Oddzial Dermatologii, Gdansk, Pomorskie, 80-462, Poland|Centrum Badan Klinicznych Pi-house Sp. Z O. O., Gdansk, Pomorskie, 80-546, Poland|Derm-art, Gdynia, Pomorskie, 81-415, Poland|AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Katowicach, Katowice, Slaskie, 40-040, Poland|Centrum Medyczne Angelius Provita, Katowice, Slaskie, 40-611, Poland|Pro Familia Altera Sp. z o.o., Katowice, Slaskie, 40-648, Poland|Dermedic Jacek Zdybski, Ostrowiec Swietokrzyski, Swietokrzyskie, 27-400, Poland|Ostrowieckie Centrum Medyczne Anna Olech Cudzik Krzysztof Cudzik s.c., Ostrowiec Swietokrzyski, Swietokrzyskie, 27-400, Poland|Solumed Centrum Medyczne, Poznan, Wielkopolskie, 60-529, Poland|AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Poznaniu, Poznan, Wielkopolskie, 60-702, Poland|Twoja Przychodnia PCM, Poznań, Wielkopolskie, 61-293, Poland|Twoja Przychodnia Szczecińskie Centrum Medyczne Sp. z o.o., Szczecin, Zachodniopomorskie, 71-500, Poland|Centrum Uslug Medycznych MaxMed, Bochnia, 32-700, Poland|Centrum Medyczne Bydgoszcz- PRATIA, Bydgoszcz, 85-796, Poland|Ambulatorium Sp. z o.o., Elblag, 82-300, Poland|Promed P. Lach R. G?owacki Sp. j., Centrum Medyczne Promed, Krakow, 31-411, Poland|Diamond Clinic Sp. z o.o., Diamond Medical Center, Krakow, 31-559, Poland|Uniwersytecki Szpital Kliniczny nr 2 Uniwersytetu Medycznego w Lodzi, Klinika Dermatologii i Wenerologii, Lodz, 90-647, Poland|Pro Life Medica Sp. z o.o. ETG Lublin, Lublin, 20-412, Poland|Twoja Przychodnia - Nowosolskie Centrum Medyczne sp. z o.o, Nowa Sól, 67-100, Poland|ETYKA Osrodek Badan Klinicznych, Olsztyn, 10-117, Poland|MICS Centrum Medyczne Torun, Torun, 87-100, Poland|Royalderm Agnieszka Nawrocka, Warszawa, 02 962, Poland|dermMEDICA Sp. z o.o. | Krzysztofa Kolumba 6, Wroc?aw, 51-503, Poland|GCM Medical Group, San Juan, 00909-3004, Puerto Rico|Hospital Clinico San Carlos, San Sebastian, Guipúzcoa, 20004, Spain|Hospital Universitario de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria, LAS Palmas, 35010, Spain|Hospital de Manises, Manises, Valencia, 46940, Spain|Hospital de La Santa Creu i Sant Pau - Dermatologia, Barcelona, 08041, Spain|National Cheng Kung University, Tainan, Tainan City, 70403, Taiwan|National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu City, 300, Taiwan|Kaohsiung Veterans General Hospital, Kaohsiung City, 81362, Taiwan|Taipei Veterans General Hospital, Taipei City, 11217, Taiwan|Mackay Memorial Hospital-Taipei branch, Taipei, Taiwan|National Taiwan University Hospital, Zhong Zheng Qu, 100, Taiwan|Velocity Clinical Research - High Wycombe - PPDS, High Wycombe, Buckinghamshire, HP11 2QW, United Kingdom|4 Medical Clinical Solutions - Swinton - PPDS, Ilford, Essex, IG1 4HP, United Kingdom|Accellacare of Yorkshire, Chorley, Lancashire, PR7 7NA, United Kingdom|Salford Royal Hospital - PPDS, Salford, Lancashire, M6 8HD, United Kingdom|Whipps Cross University Hospital, London, London, City Of, E11 1NR, United Kingdom|Accellacare of Northamptonshire, Harrow, Middlesex, HA1 3UJ, United Kingdom|Velocity Clinical Research North London - Percy Road - PPDS, London, Middlesex, N12 8BU, United Kingdom Less << |
NCT06764615 | Crohn's Disease|Ulcerative Col... More >>itis Less << | PHASE2 | NOT_YET_RECRUITING | 2029-12-30 | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.17mL 0.43mL 0.22mL |
10.86mL 2.17mL 1.09mL |
21.72mL 4.34mL 2.17mL |
Tags: Zasocitinib | Ndi-034858 | Pyridines | Amides | JAK | Organic Building Blocks | Heterocyclic Building Blocks | Epigenetics | Protein Tyrosine Kinase/RTK | Angiogenesis | Stem Cells | JAK-STAT-Signaling | Parkinson'S Disease and Alzheimer'S Disease | Tumor Development and Microenvironment Evolution | 2272904-53-5
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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