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Chemical Structure| 2328073-61-4 Chemical Structure| 2328073-61-4

Structure of ZT-12-037-01
CAS No.: 2328073-61-4

Chemical Structure| 2328073-61-4

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ZT-12-037-01 is a selective inhibitor of the serine/threonine kinase STK19, interacting with high affinity to the STK19 protein and inhibiting NRAS-driven malignant transformation of melanocytes. ZT-12-037-01 is an ATP-competitive inhibitor that suppresses NRAS phosphorylation with an IC50 of 24 nM.

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Product Details of ZT-12-037-01

CAS No. :2328073-61-4
Formula : C21H31N5O2
M.W : 385.50
SMILES Code : CC(C)N(CC1)CCC1NC2=NC(NC3CC3)=NC4=C2C=C(OC)C(OC)=C4
MDL No. :MFCD32197197
InChI Key :AMAQJTHMSLYMFT-UHFFFAOYSA-N
Pubchem ID :138911316

Safety of ZT-12-037-01

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of ZT-12-037-01

GPCR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.59mL

0.52mL

0.26mL

12.97mL

2.59mL

1.30mL

25.94mL

5.19mL

2.59mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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