Products Cited in Publications Worldwide Unmanned Aerial Vehicle Mediated Drug Delivery for First Aid

Unmanned Aerial Vehicle Mediated Drug Delivery for First Aid

Sheng, Tao; Jin, Rui; Yang, Changwei; Qiu, Ke; Wang, Mingyang; Shi, Jiaqi; Zhang, Jingyu; Gao, Yuman; Wu, Qing; Zhou, Xin; Wang, Hao; Zhang, Juan; Fang, Qin; Pan, Neng; Xue, Yanan; Wang, Yue; Xiong, Rong; Gao, Fei; Zhang, Yuqi; Lu, Haojian; Yu, Jicheng; Gu, Zhen

DOI: PMID:

Abstract

Timely administration of key medications toward patients with sudden diseases is critical to saving lives. However, slow transport of first-aid therapeutics and the potential absence of trained people for drug usage can lead to severe injuries or even death. Herein, an unmanned aerial vehicle (UAV)-mediated first-aid system for targeted delivery (uFAST) is developed. It allows unattended administration of emergency therapeutics-loaded transdermal microneedle (MN) patches toward patients to relieve symptoms by a contact-triggered microneedle applicator (CTMA). The implementability and safety of the uFAST for first aid is demonstrated in a severe hypoglycemic pig model by automatically delivering a glucagon patch with immediate and bioresponsive dual release modes. This platform technique may facilitate the development of UAV-mediated first-aid treatments for other sudden diseases.

Keywords

drug delivery ; first aid ; microneedles ; unmanned aerial vehicles

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