Home Products Cited in Publications Worldwide Evidence for singlet oxygen production from indocyanine green by electron paramagnetic resonance
BBA General Subjects,2025,1869(12):130861.
Szpunar, Magdalena; Aebisher, David; Cieniek, Bogumił; Stefaniuk, Ireneusz; Dubiel, Łukasz; Wal, Andrzej
DOI:10.1016/j.bbagen.2025.130861 PMID:40992633
Indocyanine green (ICG) is a well-known dye used for cardiovascular fluorescence imaging in medicine and a potential photosensitizer for photodynamic therapy. Using electron paramagnetic resonance (EPR), we have shown that illumination of aqueous solutions of ICG leads to the generation of singlet oxygen. The use of a selective spin trap allowed for the rate of singlet oxygen generation to be determined which provides evidence that ICG undergoes Type II photosensitization.
Singlet oxygen ; Indocyanine green ; Electron paramagnetic resonance

