Home Chemistry Heterocyclic Building Blocks Pyrrolidines Pyrrolidin-2-Ylmethanol
Oxidation: The alcohol group can be oxidized to form an aldehyde or a carboxylic acid, depending on the conditions and oxidizing agent used.
Esterification: Reaction with a carboxylic acid or acid derivative (such as an acid chloride or acid anhydride) can lead to the formation of an ester.
Acylation: The nitrogen atom in the pyrrolidine ring can undergo acylation reactions, where an acyl group is added to the nitrogen atom, forming an amide.
Reduction: The carbonyl group in the pyrrolidines can be reduced to a hydroxyl group under appropriate conditions.
Alkylation: The nitrogen atom can be alkylated by reaction with alkyl halides or sulfonates.
Substitution Reactions: The nitrogen atom can undergo substitution reactions, typical of secondary amines, such as nucleophilic substitution.
Condensation Reactions: It can participate in condensation reactions to form cyclic compounds or larger molecules.
Ring-opening Reactions: The pyrrolidine ring can undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
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(3R,5S)-5-(Hydroxymethyl)-1-methylpyrrolidin-3-ol hydrochloride
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(3R,5S)-5-(Hydroxymethyl)pyrrolidin-3-ol hydrochloride
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tert-Butyl ((3S,5R)-5-(hydroxymethyl)pyrrolidin-3-yl)carbamate
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(2S,4R)-tert-Butyl 4-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxymethyl)pyrrolidine
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(2S,4S)-tert-Butyl 4-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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(2R,4R)-tert-Butyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate hydrochloride
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(2R,4R)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate
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(2S,4S)-tert-Butyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate hydrochloride
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tert-Butyl 2,5-bis(hydroxymethyl)pyrrolidine-1-carboxylate
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(R)-(4,4-Dimethylpyrrolidin-2-yl)methanol
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tert-Butyl ((3S,5S)-5-(hydroxymethyl)pyrrolidin-3-yl)carbamate
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