Home Chemistry Heterocyclic Building Blocks Pyrroles Pyrrolo[2,1-F][1,2,4]Triazine
Nucleophilic Substitution: Pyrrolo[2,1-f][1,2,4]triazine can undergo nucleophilic substitution reactions if it has suitable leaving groups or electrophilic sites. Nucleophiles can attack the electrophilic centers and replace existing groups.
Aromatic Substitution: If there are electron-withdrawing or electron-donating groups on the pyrrolo[2,1-f][1,2,4]triazine ring, it may undergo electrophilic aromatic substitution reactions, such as nitration, halogenation, or sulfonation.
Ring Opening: Depending on the conditions and reagents used, the ring system may undergo ring-opening reactions to form open-chain compounds.
Functional Group Interconversions: Various functional groups like amines, amides, esters, and others can be introduced or modified on the pyrrolo[2,1-f][1,2,4]triazine ring through appropriate reactions such as acylation, alkylation, or amidation.
Cycloaddition Reactions: If the pyrrolo[2,1-f][1,2,4]triazine ring has suitable pi bonds, it can participate in cycloaddition reactions like Diels-Alder reactions with appropriate dienophiles.
Halogenation: Depending on the conditions and reagents, you can halogenate the pyrrolo[2,1-f][1,2,4]triazine ring, introducing halogen atoms like chlorine or bromine.
Rearrangements: In some cases, pyrrolo[2,1-f][1,2,4]triazine may undergo rearrangement reactions, leading to structural isomers.
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tert-Butyl (7-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)carbamate
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6-Bromo-2,4-dichloropyrrolo[2,1-f][1,2,4]triazine
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5-Bromo-2-chloropyrrolo[2,1-f][1,2,4]triazine
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tert-Butyl N-(7-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)-N-tert-butoxycarbonyl-carbamate
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Ethyl 2,4-dichloropyrrolo[2,1-f]-[1,2,4]triazine-6-carboxylate
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Ethyl pyrrolo[2,1-f][1,2,4]triazine-7-carboxylate
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2,4-Dichloro-6-nitropyrrolo[2,1-f][1,2,4]triazine
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7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine
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2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine
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5-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine
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7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
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4-Chloro-2-iodopyrrolo[2,1-f][1,2,4]triazine
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