
The RAS/RAF/MEK/ERK (MAPK) signaling cascade plays a crucial role in both inter- and intra-cellular communication, overseeing fundamental cell processes like growth, survival, and differentiation. This pathway integrates signals from intricate intracellular networks to execute various cellular functions. Despite the initial identification of the core components of the MAPK pathways almost four decades ago, ongoing discoveries persist in complicating a comprehensive understanding of the molecular mechanisms governing this pathway.
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