Diazirines are compact, photoactivatable groups commonly used in chemical biology to study protein interactions. Upon UV irradiation (typically ~350 nm), the diazirine ring forms a reactive carbene intermediate that rapidly inserts into nearby C–H, N–H, or O–H bonds, enabling covalent crosslinking of transient protein–protein or protein–ligand interactions. This makes them powerful tools for target identification and interactome mapping in live-cell environments.
A14215132219371-87-497%
3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)azetidine hydrochloride$627.00/50mg Detail
A15111702230798-60-298%
3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)pyrrolidine hydrochloride$717.00/100mg Detail
A15106922219407-49-398%
4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)piperidine hydrochloride$791.00/250mg Detail
A2690799N/A95%
9-(3-Methyl-3H-diazirin-3-yl)nonanoic acid$216.00/25mg Detail
A2690797N/A95%
10-(3-Methyl-3H-diazirin-3-yl)decanoic acid$339.00/50mg Detail
A1488123655224-73-098%
N-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide$522.00/50mg Detail