Diazirines

Diazirines are compact, photoactivatable groups commonly used in chemical biology to study protein interactions. Upon UV irradiation (typically ~350 nm), the diazirine ring forms a reactive carbene intermediate that rapidly inserts into nearby C–H, N–H, or O–H bonds, enabling covalent crosslinking of transient protein–protein or protein–ligand interactions. This makes them powerful tools for target identification and interactome mapping in live-cell environments.

Diazirines

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)azetidine hydrochloride
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A14215132219371-87-497%

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)azetidine hydrochloride

$627.00/50mg Detail

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)pyrrolidine hydrochloride
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A15111702230798-60-298%

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)pyrrolidine hydrochloride

$717.00/100mg Detail

4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)piperidine hydrochloride
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A15106922219407-49-398%

4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)piperidine hydrochloride

$791.00/250mg Detail

Fmoc-Photo-Leu-OH
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A14631151360651-24-698%

Fmoc-Photo-Leu-OH

$330.00/50mg Detail

DiZPK
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A7913851337883-32-598%

DiZPK

$318.00/50mg Detail

DiAzKs
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A12097751253643-88-797%

DiAzKs

$153.00/5mg Detail

H-Photo-Lys-OH·HCl
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A13617032421187-79-197%

H-Photo-Lys-OH·HCl

$867.00/100mg Detail

9-(3-Methyl-3H-diazirin-3-yl)nonanoic acid
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A2690799N/A95%

9-(3-Methyl-3H-diazirin-3-yl)nonanoic acid

$216.00/25mg Detail

10-(3-Methyl-3H-diazirin-3-yl)decanoic acid
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A2690797N/A95%

10-(3-Methyl-3H-diazirin-3-yl)decanoic acid

$339.00/50mg Detail

N-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide
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A1488123655224-73-098%

N-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzamide

$522.00/50mg Detail

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