Home Chemistry Organic Building Blocks Trifluoromethyls (Trifluoromethyl)Benzene
These compounds have the same murcko framework: benzene,and at least 1 kind of functional groups( —CF3).
Nucleophilic Aromatic Substitution (SNAr): Depending on the nature of the nucleophile, nucleophilic aromatic substitution reactions can occur. The trifluoromethyl group can influence the reactivity and regioselectivity of these reactions.
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1-(2-Fluoro-6-(trifluoromethyl)benzyl)urea
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(R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethanol
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4-Chloro-3-(trifluoromethyl)phenyl isocyanate
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Ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
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2-(Methylsulfonyl)-4-(trifluoromethyl)benzoic acid
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4-Isothiocyanato-2-(trifluoromethyl)benzonitrile
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