Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1-Ethoxy-2-Fluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OC2H5).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Oxidation: Ethoxybenzene can be oxidized to form the corresponding 【phenol|https://www.ambeed.com/phenols.html】 using strong oxidizing agents like potassium permanganate (KMnO4) or chromic acid (H2CrO4).
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(3-Chloro-5-ethoxy-4-fluorophenyl)boronic acid
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(6-Bromo-3-ethoxy-2-fluorophenyl)boronic acid
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(4-Ethoxy-2,3-difluorophenyl)boronic acid
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(3-Chloro-4-ethoxy-5-fluorophenyl)boronic acid
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(6-Bromo-2-ethoxy-3-fluorophenyl)boronic acid
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