Home Chemistry Organic Building Blocks Fluorinated Building Blocks 1-Fluoro-4-Methoxybenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OCH3).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Borohydride Demethylation: Methoxybenzene can undergo demethylation reactions using sodium borohydride (NaBH4) in the presence of a proton source, resulting in the formation of phenol.
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(2,6-Difluoro-3,5-dimethoxyphenyl)methanol
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(3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid
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2,3-Difluoro-6-methoxyphenylboronic acid
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