Home Chemistry Heterocyclic Building Blocks Pyridines 2-Bromo-6-Chloropyridine
Substitution Reactions: The bromine and chlorine atoms are both susceptible to nucleophilic substitution reactions. For instance, they can be replaced by other nucleophiles such as hydroxide ions, amines, or thiols, leading to the formation of different substituted pyridine derivatives.
Metalation Reactions: The compound can undergo metalation reactions with strong bases, where a metal atom replaces one of the halogen atoms, forming a metal-halogen bond.
Cross-Coupling Reactions: The compound can participate in cross-coupling reactions, such as Suzuki, Heck, or Stille reactions, where the halogen atoms serve as leaving groups, enabling the formation of carbon-carbon bonds with other organic molecules.
Redox Reactions: The bromine and chlorine atoms can participate in redox reactions, where they can be either reduced or oxidized, leading to the formation of different functional groups on the pyridine ring.
Halogenation Reactions: The compound can undergo further halogenation reactions, where the bromine or chlorine atoms can be replaced by other halogens (e.g., fluorine or iodine) under appropriate reaction conditions.
Ring Closure Reactions: The compound can participate in ring-closure reactions to form heterocyclic compounds under certain reaction conditions.
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6-Bromo-2-chloro-3-methoxy-4-methylpyridine
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tert-Butyl (2-bromo-6-chloropyridin-3-yl)carbamate
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