Home Chemistry Heterocyclic Building Blocks Pyridines 2-Chloro-5-Methylpyridine
Nucleophilic Substitution: The chlorine atom can be replaced by a nucleophile such as hydroxide ion or amine groups (-NH2), resulting in the formation of substituted pyridine derivatives.
Electrophilic Aromatic Substitution (EAS): The electron-rich pyridine ring can undergo substitution reactions with electrophilic reagents. For example, it can react with strong electrophiles like nitronium ion or acyl chlorides to form substituted products.
Metalation Reactions: The pyridine ring can be metalated by strong bases such as butyllithium or Grignard reagents, leading to the formation of organometallic compounds.
Oxidation Reactions: The methyl group can undergo oxidation to yield corresponding carboxylic acids or ketones under suitable conditions, such as with strong oxidizing agents like potassium permanganate (KMnO4) or chromic acid (H2CrO4).
Reduction Reactions: The chlorine atom or the pyridine ring can undergo reduction under appropriate conditions, yielding products such as chloroalkanes or saturated pyridine derivatives.
Condensation Reactions: 2-chloro-5-methylpyridine can participate in condensation reactions with appropriate reagents to form heterocyclic compounds or other organic products.
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1-(2-Chloro-5-methylpyridin-4-yl)ethanone
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2-CHLORO-5-METHYLPYRIDINE-3-BORONIC ACID 98
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1-(2-Chloro-5-methylpyridin-3-yl)ethanone
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2-Chloro-5-methylpyridine-3-sulfonyl chloride
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tert-Butyl (6-chloro-3-methylpyridin-2-yl)carbamate
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