Home Chemistry Heterocyclic Building Blocks Pyridines 3-(Cyclopropylmethyl)Pyridine
Aromatic Electrophilic Substitution: The pyridine ring in 3-(cyclopropylmethyl)pyridine can undergo electrophilic aromatic substitution reactions with electrophiles. For example, it can react with strong electrophiles like nitronium ions (NO2+) to introduce substituents on the pyridine ring.
Nucleophilic Substitution: The cyclopropylmethyl group can undergo nucleophilic substitution reactions. For instance, the cyclopropylmethyl halide derivative can undergo nucleophilic substitution with various nucleophiles, such as amines, to form substituted products.
Reduction: 3-(cyclopropylmethyl)pyridine can be reduced to form saturated compounds if it is treated with reducing agents like lithium aluminum hydride (LiAlH4) or hydrogen gas (H2) over a metal catalyst.
Oxidation: It can also undergo oxidation reactions under suitable conditions. For example, it can be oxidized to form pyridine N-oxide using oxidizing agents like hydrogen peroxide (H2O2).
Alkylation: The pyridine nitrogen can be alkylated using alkylating agents, which can lead to the formation of N-alkylated derivatives of 3-(cyclopropylmethyl)pyridine.
Acylation: The pyridine nitrogen can be acylated with acylating agents, resulting in N-acylated derivatives.
Grignard Reactions: 3-(cyclopropylmethyl)pyridine can react with Grignard reagents, leading to the formation of new carbon-carbon bonds.
Heterocyclic Chemistry: The pyridine ring in the compound can participate in various heterocyclic reactions, such as the synthesis of fused heterocyclic compounds or the formation of heterocyclic rings through cyclization reactions.
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Cyclopropyl(pyridin-3-yl)methanamine dihydrochloride
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(6-Chloropyridin-3-yl)(cyclopropyl)methanamine dihydrochloride
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(6-Chloropyridin-3-yl)(cyclopropyl)methanamine
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(5-Chloropyridin-3-yl)(cyclopropyl)methanamine dihydrochloride
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