Home Chemistry Heterocyclic Building Blocks Pyridines 3-Methylpyridine 1-Oxide
Nucleophilic Substitution: Since it contains a nitrogen atom with lone pair electrons, it can undergo nucleophilic substitution reactions at the nitrogen atom. For instance, it can react with electrophiles to form substituted products.
Oxidation: Being an N-oxide, it may undergo further oxidation under appropriate conditions. This could lead to the formation of products with additional oxygen functionalities.
Acid-Base Reactions: The pyridine ring can undergo protonation or deprotonation reactions depending on the pH of the solution. This can lead to the formation of salts or different protonation states of the molecule.
Metal Complexation: The lone pair on the nitrogen atom can coordinate with metal ions, forming metal complexes. This can be significant in catalytic reactions or in the formation of coordination compounds.
Ring-Opening Reactions: Under certain conditions, the pyridine ring may undergo ring-opening reactions leading to the formation of open-chain compounds.
Substitution Reactions on the Methyl Group: The methyl group attached to the pyridine ring can undergo various substitution reactions, such as electrophilic aromatic substitution or nucleophilic substitution.
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2-(Hydroxymethyl)-4-methoxy-3,5-dimethylpyridine 1-oxide
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