Home Chemistry Heterocyclic Building Blocks Pyridines 6-Methylpicolinic Acid
Acid-Base Reactions: Being a carboxylic acid, it can undergo typical acid-base reactions. It can react with bases to form salts, and with strong bases, it can undergo deprotonation to form the corresponding carboxylate anion.
Esterification: It can undergo esterification reactions with alcohols in the presence of acid catalysts to form esters.
Halogenation: The aromatic ring can undergo halogenation reactions, such as bromination or chlorination, typically in the presence of a halogenating agent and a catalyst.
Oxidation: It can undergo oxidation reactions to form various products depending on the conditions. For example, it can be oxidized to the corresponding pyridine carboxylic acid.
Reduction: Under suitable conditions, it can be reduced to form the corresponding methylpyridine or further reduced to form piperidine derivatives.
Substitution Reactions: It can undergo nucleophilic aromatic substitution reactions, where the substituent on the aromatic ring can be replaced by another group.
Metal Complex Formation: The nitrogen atom can coordinate with metal ions to form complexes, particularly with transition metals.
Condensation Reactions: It can undergo condensation reactions with other compounds containing active hydrogen atoms, such as in the synthesis of heterocyclic compounds.
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4-Chloro-6-methylpicolinic acid hydrochloride
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5-Fluoro-6-methylpyridine-2-carboxylic acid
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