Home Life Science Amino Acids Amino Acid Derivatives Benzyl (((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Glycinate
Hydrolysis: Benzyl (((9H-fluoren-9-yl)methoxy)carbonyl)glycinate may undergo hydrolysis when exposed to water or an aqueous solution of an acid or base. This could result in the cleavage of the ester bond, producing benzyl alcohol, glycine, and the remaining fluorenylmethoxycarbonyl (Fmoc) group.
Amine Reactions: The glycinate group contains an amine functional group. This can react with various reagents or reactants. For example, it can undergo reactions with acid chlorides to form amides or with aldehydes or ketones in reductive amination reactions to form secondary amines.
Benzyl Group Reactions: The benzyl group can undergo various reactions, including oxidation, reduction, and substitution reactions. For instance, the benzyl group can be oxidized to form a benzaldehyde or further to benzoic acid.
Protection and Deprotection: The Fmoc group is commonly used as a protecting group for amines in organic synthesis. It can be selectively removed using a suitable reagent like piperidine to reveal the free amine group.
Cleavage: Depending on the specific chemical context and reaction conditions, the molecule may undergo cleavage reactions at various points, leading to the formation of smaller fragments.
Cross-coupling Reactions: The benzyl group can participate in cross-coupling reactions, such as Suzuki coupling or Heck coupling, to form new carbon-carbon bonds.
Reductive Reactions: Depending on the reaction conditions and reagents, the carbonyl group in the Fmoc group or other carbonyl groups in the molecule can undergo reduction reactions to produce alcohols or aldehydes.
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(S)-Benzyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-cyanopropanoate
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