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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 18531-99-2 Chemical Structure| 18531-99-2
Chemical Structure| 18531-99-2

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Synonyms: (S)-1,1'-Bi-2,2'-naphthol; S-(-)-2,2'-Dihydroxy-1,1'-binaphthyl; (S)-(-)-1,1'-Bi-2-naphthol

4.5 *For Research Use Only !

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Product Details of (S)-BINOL

CAS No. :18531-99-2
Formula : C20H14O2
M.W : 286.32
SMILES Code : OC1=CC=C2C=CC=CC2=[C@]1[C@]3=C4C=CC=CC4=CC=C3O
Synonyms :
(S)-1,1'-Bi-2,2'-naphthol; S-(-)-2,2'-Dihydroxy-1,1'-binaphthyl; (S)-(-)-1,1'-Bi-2-naphthol
MDL No. :MFCD00004068
InChI Key :PPTXVXKCQZKFBN-UHFFFAOYSA-N
Pubchem ID :11762

Safety of (S)-BINOL

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H315-H319
Precautionary Statements:P301+P310+P330-P302+P352-P305+P351+P338
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of (S)-BINOL

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 18531-99-2 ]

[ 18531-99-2 ] Synthesis Path-Downstream   1~11

  • 1
  • [ 10226-29-6 ]
  • [ 18531-99-2 ]
  • (S)-6-[2'-(5-oxohexyloxy)-[1,1']binaphthalenyl-2-yloxy]hexan-2-one [ No CAS ]
  • 2
  • [ 40138-16-7 ]
  • [ 18531-99-2 ]
  • [ 180683-64-1 ]
  • tert-butyl (E,1S,2S)-2-((2-((Sa)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaborepin-4-yl)phenyl)methylideneamino)cyclohexylcarbamate [ No CAS ]
  • 3
  • [ 1095-03-0 ]
  • [ 18531-99-2 ]
  • C26H17BO3 [ No CAS ]
  • 4
  • [ 18531-99-2 ]
  • [ 83883-26-5 ]
  • (S)-(-)-1,1'-binaphthyl-2,2'-diyl bis(4-(6-(acryloyloxy)hexyl)oxy)benzoate [ No CAS ]
  • 5
  • [ 18531-99-2 ]
  • [ 118591-58-5 ]
  • 2-(2-{2'-[2-(2-Hydroxy-ethoxy)-ethoxy]-[1,1']binaphthalenyl-2-yloxy}-ethoxy)-ethanol [ No CAS ]
  • 6
  • [ 1095-03-0 ]
  • [ 7732-18-5 ]
  • [ 18531-99-2 ]
  • C32H22B2O5 [ No CAS ]
  • 7
  • [ 1095-03-0 ]
  • [ 62506-88-1 ]
  • [ 18531-99-2 ]
  • C40H24BO4(1-)*C20H17N*H(1+) [ No CAS ]
  • 8
  • [ 1095-03-0 ]
  • [ 1252653-25-0 ]
  • [ 18531-99-2 ]
  • C40H24BO4(1-)*C28H34N2O2*H(1+) [ No CAS ]
  • 9
  • [ 1091606-67-5 ]
  • [ 40138-16-7 ]
  • [ 18531-99-2 ]
  • C53H39BNO2P [ No CAS ]
YieldReaction ConditionsOperation in experiment
In chloroform; at 50℃; for 0.5h;Inert atmosphere; General procedure: A 0.5-dram vial equipped with a magnetic stirring bar wascharged with stock solutions of 2-formylphenylboronicacid (0.10 M, 200 μL, 0.02 mmol), pinacol (0.10 M, 200 μL,0.02mmol) and 5c (0.25M, 80 μL, 0.02mmol). The solventswere removed in vacuo. CHCl3 (50 μL) was added undera positive pressure of argon. The reaction was stirred at 50C for 30 min. The volatiles were then removed under highvacuum. [Pd(allyl)Cl]2 (0.13 M in CHCl3, 40 μL, 5.0 μmol)was added under a positive pressure of argon and thereaction stirred at 23C for 15 min. Allyl acetate rac-7(0.01 M in CHCl3, 10 μL, 0.10 mmol), bis(trimethylsilyl)acetamide (49 μL, 0.20 mmol), diethyl malonate (30 μL,0.20 mmol) and potassium acetate (0.50 mg, 5.0 μmol)were added sequentially. The reaction was stirred at 23Cfor 24 hours. The crude reaction mixture was then filteredthrough a short plug of Celite and rinsed three times withCH2Cl2. An aliquot of the reaction mixture (5.0 μL) wasused for conversion and ee analyses using HPLC. HPLCconditions: Chiralpak IA column, 2.0% isopropanol/hexanes,0.5 mL/min, 254 nm, tr: 22.9 and 29.2min.
  • 10
  • [ 30309-80-9 ]
  • [ 602-09-5 ]
  • [ 18531-94-7 ]
  • [ 18531-99-2 ]
  • (S)-2'-hydroxy-[1,1'-binaphthalen]-2-yl di-o-tolylphosphinate [ No CAS ]
  • 11
  • [ 30309-80-9 ]
  • [ 602-09-5 ]
  • [ 18531-99-2 ]
  • (R)-2'-hydroxy-[1,1'-binaphthalen]-2-yl di-o-tolylphosphinate [ No CAS ]
 

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