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Chemical Structure| 3775-72-2

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Product Details of (S)-3-Aminobutyric Acid

CAS No. :3775-72-2
Formula : C4H9NO2
M.W : 103.12
SMILES Code : C[C@H](N)CC(O)=O
MDL No. :MFCD00270347
InChI Key :OQEBBZSWEGYTPG-VKHMYHEASA-N
Pubchem ID :2761506

Safety of (S)-3-Aminobutyric Acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of (S)-3-Aminobutyric Acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3775-72-2 ]

[ 3775-72-2 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 623-43-8 ]
  • [ 3775-72-2 ]
  • [ 3775-73-3 ]
  • 2
  • ethyl 3-butanamidobutanoate [ No CAS ]
  • [ 3775-72-2 ]
  • [ 3775-73-3 ]
  • [ 1379442-82-6 ]
  • [ 1270112-24-7 ]
  • [ 5303-65-1 ]
  • [ 5303-65-1 ]
  • ethyl (R)-3-butanamidobutanoate [ No CAS ]
  • ethyl (S)-3-butanamidobutanate [ No CAS ]
  • 4
  • [ 3775-72-2 ]
  • [ 5699-54-7 ]
  • [ 1135149-02-8 ]
  • [ 15099-85-1 ]
  • [ 91298-67-8 ]
  • C41H65N6O8Pol [ No CAS ]
  • 5
  • [ 3775-72-2 ]
  • [ 5699-54-7 ]
  • [ 1135149-02-8 ]
  • [ 91298-67-8 ]
  • C38H67N6O8Pol [ No CAS ]
  • 6
  • [ 3775-72-2 ]
  • [ 5699-54-7 ]
  • [ 1135149-02-8 ]
  • [ 91298-67-8 ]
  • C37H65N6O8Pol [ No CAS ]
  • 7
  • [ 3775-72-2 ]
  • [ 5699-54-7 ]
  • [ 1135149-02-8 ]
  • [ 91298-67-8 ]
  • C35H61N6O8Pol [ No CAS ]
  • 8
  • [ 3775-72-2 ]
  • [ 5699-54-7 ]
  • [ 1135149-02-8 ]
  • [ 91298-67-8 ]
  • β-L-Homoisoleucin [ No CAS ]
  • C38H67N6O8Pol [ No CAS ]
  • 9
  • [ 3775-72-2 ]
  • [ 5699-54-7 ]
  • [ 1135149-02-8 ]
  • [ 91298-67-8 ]
  • β-L-Homoisoleucin [ No CAS ]
  • C38H67N6O8Pol [ No CAS ]
  • 10
  • cyclombandakamine A<SUB>1</SUB> [ No CAS ]
  • [ 56-41-7 ]
  • [ 338-69-2 ]
  • [ 3775-72-2 ]
  • [ 3775-73-3 ]
  • [ 3913-67-5 ]
  • [ 29475-64-7 ]
  • (S)-3-(N-methylamino)butanoic acid [ No CAS ]
  • (R)-N-methyl-3-aminobutyric acid [ No CAS ]
  • 11
  • cyclombandakamine A<SUB>2</SUB> [ No CAS ]
  • [ 56-41-7 ]
  • [ 338-69-2 ]
  • [ 3775-72-2 ]
  • [ 3775-73-3 ]
  • [ 3913-67-5 ]
  • [ 29475-64-7 ]
  • (S)-3-(N-methylamino)butanoic acid [ No CAS ]
  • (R)-N-methyl-3-aminobutyric acid [ No CAS ]
  • 12
  • [ 3775-72-2 ]
  • [ 61477-39-2 ]
YieldReaction ConditionsOperation in experiment
47% With sodium tetrahydroborate; zinc(II) chloride; In tetrahydrofuran; at 20 - 60℃; for 3.5h; Add 2 mL of anhydrous tetrahydrofuran and 43 g of anhydrous zinc chloride to the 2L autoclave (with little heat dissipation). Carefully add 24 g of sodium borohydride (note the exotherm and gas production). Stirred at room temperature for 30 minutes and then warmed to 50-60 ° C for 3 hours. After cooling to room temperature, 49 g of the above white solid was added portionwise and the temperature was controlled at 10 to 40 ° C. After the addition was complete, the temperature was slowly raised to reflux for 24 hours. The system became a gray suspension system, cooled to 10-15 ° C, slowly added 25 ml of methanol and 8 g of a 40percent aqueous solution of sodium hydroxide, and the temperature was controlled at 10 to 40 ° C. After adding, stir at room temperature for 3-5 hours. Filtered, washed with THF and filtered to give a colorless liquid. After concentration and distillation under reduced pressure (10 to 65 ° C), 17 g of a clear viscous liquid R-3-aminobutanol was obtained in 47percent yield. Purity 99.1percent, ee99.2percent.
 

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