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Chemical Structure| 634-36-6 Chemical Structure| 634-36-6
Chemical Structure| 634-36-6

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1,2,3-Trimethoxybenzene is an anisole compound primarily used as an intermediate in organic synthesis.

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Product Details of 1,2,3-Trimethoxybenzene

CAS No. :634-36-6
Formula : C9H12O3
M.W : 168.19
SMILES Code : COC1=C(OC)C(OC)=CC=C1
MDL No. :MFCD00008358
InChI Key :CRUILBNAQILVHZ-UHFFFAOYSA-N
Pubchem ID :12462

Safety of 1,2,3-Trimethoxybenzene

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of 1,2,3-Trimethoxybenzene

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 634-36-6 ]

[ 634-36-6 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 634-36-6 ]
  • [ 16932-45-9 ]
  • 2
  • [ 634-36-6 ]
  • [ 19676-64-3 ]
YieldReaction ConditionsOperation in experiment
With potassium peroxymonosulfate; In d(4)-methanol; water-d2; at 20℃; for 5h; General procedure: To an NMR tube, 8.4 mg (50 µmoles) of 1 and 2.2 mg (30 µmoles) of tBuOH (used as an internal standard) in a 750 µL solution of 10% (v/v) d3-ACN in D2O were added. A 1H-NMR spectrum was recorded as a zero point (time = 0). A stock solution of 400 mM Oxone in 10% (v/v) d3-ACN in D2O was prepared and a 250 µL aliquot of the Oxone solution was added to the NMR tube to initiate the reaction. The reaction was followed by 1H-NMR spectroscopy over the course of 5 hrs at room temperature. The yields reported were based on the integration of aromatic peaks against the internal standard. This procedure was repeated for each of the different mol equivalents of Oxone, for the different cosolvents, and substrates.
  • 3
  • [ 634-36-6 ]
  • [ 151-50-8 ]
  • [ 16932-49-3 ]
  • 4
  • [ 634-36-6 ]
  • [ 33130-04-0 ]
  • 6
  • [ 634-36-6 ]
  • [ 530-55-2 ]
  • [ 19676-64-3 ]
YieldReaction ConditionsOperation in experiment
With potassium peroxymonosulfate; In [D3]acetonitrile; water-d2; at 20℃; for 5h; General procedure: To an NMR tube, 8.4 mg (50 µmoles) of 1 and 2.2 mg (30 µmoles) of tBuOH (used as an internal standard) in a 750 µL solution of 10% (v/v) d3-ACN in D2O were added. A 1H-NMR spectrum was recorded as a zero point (time = 0). A stock solution of 400 mM Oxone in 10% (v/v) d3-ACN in D2O was prepared and a 250 µL aliquot of the Oxone solution was added to the NMR tube to initiate the reaction. The reaction was followed by 1H-NMR spectroscopy over the course of 5 hrs at room temperature. The yields reported were based on the integration of aromatic peaks against the internal standard. This procedure was repeated for each of the different mol equivalents of Oxone, for the different cosolvents, and substrates.
  • 7
  • [ 634-36-6 ]
  • [ 530-55-2 ]
  • [ 3117-02-0 ]
  • [ 19676-64-3 ]
YieldReaction ConditionsOperation in experiment
With potassium peroxymonosulfate; In [D3]acetonitrile; water-d2; tert-butyl alcohol; at 20℃; for 5h;Schlenk technique; Inert atmosphere; To an NMR tube, 8.4 mg (50 µmoles) of 1 and 2.2 mg (30 µmoles) of tBuOH (used as an internal standard) in a 750 µL solution of 10% (v/v) d3-ACN in D2O were added. A 1H-NMR spectrum was recorded as a zero point (time = 0). A stock solution of 400 mM Oxone in 10% (v/v) d3-ACN in D2O was prepared and a 250 µL aliquot of the Oxone solution was added to the NMR tube to initiate the reaction. The reaction was followed by 1H-NMR spectroscopy over the course of 5 hrs at room temperature. The yields reported were based on the integration of aromatic peaks against the internal standard. This procedure was repeated for each of the different mol equivalents of Oxone, for the different cosolvents, and substrates.
  • 8
  • [ 634-36-6 ]
  • [ 75-86-5 ]
  • [ 16932-49-3 ]
 

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