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Chemical Structure| 97628-92-7 Chemical Structure| 97628-92-7

Structure of 97628-92-7

Chemical Structure| 97628-92-7

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Product Details of [ 97628-92-7 ]

CAS No. :97628-92-7
Formula : C12H13NO4
M.W : 235.24
SMILES Code : C(=O)(OCC1=CC=CC=C1)N2CC(C2)C(=O)O
MDL No. :MFCD09027504
InChI Key :PVJPBKZGIUAESY-UHFFFAOYSA-N
Pubchem ID :10988214

Safety of [ 97628-92-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 97628-92-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 97628-92-7 ]

[ 97628-92-7 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 97628-92-7 ]
  • [ 18107-18-1 ]
  • [ 757239-60-4 ]
YieldReaction ConditionsOperation in experiment
96%
Stage #1: at 0℃;
Stage #2: With acetic acid In methanol; hexanes; toluene
1-BENZYLOXYCARBONYL-3-AZETIDINECARBOXYLIC acid (from step (i); 9.3g, 39. 6MMOL) was dissolved in methanol (LOOML) and toluene (100mL), and cooled to 0°C. A solution of 2M trimethylsilyldiazomethane in hexanes was then added dropwise until bubbling had ceased and the yellow colour persisted. Acetic acid was then added dropwise until the yellow colour disappeared. Concentration of the solution yielded the title compound as an oil (9.48G, 38mmol, 96percent). IH NMR (400MHZ, CDC13) : 8 7.36-7. 31 (5H, m), 5.10 (2H, s), 4.19 (4H, D, J7. 8Hz), 3.75 (3H, s), 3.39 (1H, quintet, J 7. 8HZ).
References: [1] Patent: WO2004/78750, 2004, A1, . Location in patent: Page 81.
  • 2
  • [ 186581-53-3 ]
  • [ 97628-92-7 ]
  • [ 757239-60-4 ]
YieldReaction ConditionsOperation in experiment
98% at 20℃; for 4 h; EXAMPLE 27B; 1-benzyl 3-methylazetidine-1,3-dicarboxylate A solution of Example 27A (4.8 g, 20.3 mmol) in ether (100 ml) was treated with diazomethane (100 ml in ether, 60 mmol) at room temperature for 4 hours. Removal of the volatiles gave Example 27B (4.8 g Yield: 98percent). MS (DCI/NH3) m/z 250 (M+H)+.
References: [1] Patent: US2006/229289, 2006, A1, . Location in patent: Page/Page column 19.
 

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